简介：Citation：WangJY,ShaoY,ZhouFX,etal.Clinicalobservationofphacoemulsificationcombinedgoniosynechialysisintreatingabsoluteglaucomaaftertrabeculectomy.GuojiYankeZazhi（IntEyeSci）2014；14（10）：1818-1821目的：观察白内障超声乳化联合房角分离术治疗小梁切除术后绝对期青光眼的效果。方法：对16例16眼绝对期青光眼施行白内障超声乳化联合房角分离术,随访6~12mo,观察眼压、前房深度、术前术后用药种类（数量）、术前与术后1mo焦虑和抑郁状态、眼表症状等情况。结果：行白内障超声乳化联合房角分离术后,眼压明显下降。术前眼压平均值35.00±15.43mmHg,术后第1d眼压平均值为12.00±6.69mmHg；术后6mo为15.00±4.26mmHg；术后12mo为15.3±5.2mmHg。术后眼压与术前比较差异有统计学意义（t=6.22,P〈0.05）。术前前房深度为1.45±0.19mm,术后增加至3.37±0.13mm,差异有统计学意义（t=6.65,P〈0.05）。术后仅2例患者需用2种降眼压药物,2例患者需1种降眼压药物。术后12mo16例患者的焦虑和抑郁状态均有所改善；16例患者眼胀、眼痛等主观不适症状均减轻；所有患者眼球都得以保留,且无严重并发症。结论：超声乳化联合房角分离治疗小梁切除术后绝对期青光眼是安全、有效的手术选择。

简介：AIM:Tocharacterizetemporalpatternofresolutionandrecurrenceofnaivechoroidalneovascularization(CNV)secondarytowetage-relatedmaculardegeneration(AMD)treatedwithintravitrealbevacizumabonasneededregimen,andtoanalyzebaselineriskfactorsforCNVresolutionorrecurrence.METHODS:Ninety-oneeyesof80patientswithnewlydiagnosedwetAMDwereretrospectivelystudied.Alleyesweretreatedwitharoundofthreemonthlyintravitrealbevacizumabinjections,followedbyoneadditional’bonus’injectionafterresolutionofCNVactivity.Duringfollow-up,eyesweremonitoredwithfluoresceinangiography,opticalcoherencetomography,andbest-correctedvisualacuity(BCVA).IncaseofrecurrencesofCNVactivity,eyeswereretreatedwithotherroundsofbevacizumabinjectionsfollowingthesametreatmentprotocol.RESULTS:Overamedianfollow-upof532d,themedianresolutiontimeofCNVactivityinthefirst,second,andthirdtreatmentroundwas98d,126d,and111d,respectively.Themedianrecurrencetimeforthethreeroundswas154d,126d,and151d,respectively.Nosignificantdifferenceinresolutiontime(P=0.09)orinrecurrencetime(P=0.11)wasdetectedamongtreatmentrounds.Age(P=0.0082)andlensstatus(P=0.035)werefoundtobeassociatedwithCNVresolution;forevery1-yearincreaseinagetherewas4%greaterchanceofCNVresolution;Phakiceyesdemonstrateda33%betterchancetoexperienceCNVresolutionthanpseudophakiceyes.ForCNVrecurrence,lensstatus(P=0.0009)andgender(P=0.0446)werefoundtobepredictive;pseudophakiceyeshada3.69-foldgreaterrisktoexperiencerecurrenceofCNVactivitycomparedtophakiceyes;maleshada2.19-foldgreaterrisktoexperiencerecurrenceofCNVactivitythanfemales.NosignificantBCVAchangesamongthreetreatmentroundswerenoted(P=0.56).CONCLUSION:ResolutiontimeandrecurrencetimeofCNVactivitywerenotsignificantlydifferentamongtreatmentrounds,suggestingabsenceoftachyphylaxistobevacizumab.Acautiousdecisionshouldbemadeupondisco