摘要
Eatmore‘green’oreat‘fiveaday’isoneofthemostimportanthealthylifestylebehavioursinthe21century.Aimingtofightcancereffectively,morethanhalfpatientsusevitaminsorherbsconcurrentlywithconventionalanticancertreatment.Flavonoidsorpolyphenolsexistinginvegetables,fruitsandgreenteaarecommonplantpigmentswithantioxidantpropertiesandconsideredactingascancerpreventingoranti-canceragents.RecentlyitwasfoundthatsomeflavonoidsandvitaminCindietorsupplementshaveantagonisticeffectwiththeanti-cancerdrugbortezomib.Bortezomibisaspecificinhibitorforproteasomeandiscurrentlyusedfortreatmentofrelapsedandrefractorymultiplemyeloma.Despiteitssuccessfulratesintreatingmultiplemyelomaandothersolidtumors,itisunabletokillleukemiccellsintheblood.ItwasrecentlyrevealedthatsomeflavonoidsandvitaminCpresentingreenleavesandgreenteasinthebloodcanneutralizebortezomibbydirectlyinteractionbetweentwochemicals.Herewesummarizewhydietaryflavonoidsshouldbeavoidedinpatientswhotakebortezomibaschemotherapeuticdrug.
出版日期
2013年04月14日（中国期刊网平台首次上网日期，不代表论文的发表时间）
