Impairment of extra-high frequency auditory thresholds in subjects with elevated levels of fasting blood glucose

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摘要 ThisstudywasperformedtoassesswhetherthereisanassociationbetweenelevatedFastingBloodGlucose(FBG)andhearingimpairmentinBangladeshipopulation.Atotalof142subjects(72withelevatedFBG;70control)wereincludedinthestudy.Themeanauditorythresholdsofthecontrolsubjectsat1,4,8and12kHzfrequencieswere6.35±0.35,10.07±0.91,27.57±1.82,51.28±3.01dBSPL(decibelsoundpressurelevel),respectivelyandthatofthesubjectswithelevatedFBGwere8.33±0.66,14.37±1.14,38.96±2.23,and71.11±2.96dB,respectively.TheauditorythresholdsofthesubjectswithelevatedFBGweresignificantly(p<0.05)higherthanthecontrolsubjectsatalltheabovefrequencies,althoughhearingimpairmentwasmostevidentlyobservedatanextra-high(12kHz)frequency.Subjectswithalongdurationofdiabetes(>10years)showedsignificantly(p<0.05)higherlevelofauditorythresholdsat8and12kHz,butnotat1and4kHzfrequencies,comparedtosubjectswithshorterdurationofdiabetes(10years).Inaddition,basedonthedataofoddsratio,moreacuteimpairmentofhearingattheextra-highfrequencywasobservedindiabeticsubjectsofbotholder(>40years)andyounger(40years)agegroupscomparedtotherespectivecontrols.Thebinarylogisticregressionanalysisshoweda5.79-foldincreaseintheoddsofextra-highfrequencyhearingimpairmentindiabeticsubjectsafteradjustmentforage,genderandBMI.Thisstudyprovidesconclusiveevidencethatauditorythresholdatanextra-highfrequencycouldbeasensitivemarkerforhearingimpairmentindiabeticsubjects.
机构地区 不详
出版日期 2018年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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