Structural changes of neurons in hippocampus from infantile rats exposed to hyperbaric oxygen-中国期刊网

摘要 Objective:Toinvestigateifhyperbaricoxygen(HBO)mayinducestructuralchangesofneuronsinhippocampusfrominfactileratsandifthechangesarereversible.Methods:All27healthySDinfantileratswereexposedtoHBO(0.25MPa)orhyperbaricair(HBA)for1to3courses(10daysas1course).Thehippocampuswastakenattheendofeachcoursetoobserveitsmorphologybylightmicroscopeandelectronmicroscope.Results:HBOexposureinducedcapillarydilation,nuclearmembranewindingorblurringandsomemitochondriaswellingwithitscristablurringinneurons.Thechangesoccurredafter1courseexposureandbecamesignificantwithtime.Mostofthechangesrecovered20daysafterstoppingexposure.NochangewasfoundafterHBAexposure.Conclusions:Long-termHBOexposurecancausecapillarydilationandultrastructuralinjuryofneuronsinhippocampusfrominfantilerats.Thedamageisnotserious,butreversible.

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Structural changes of neurons in hippocampus from infantile rats exposed to hyperbaric oxygen

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Structural changes of neurons in hippocampus from infantile rats exposed to hyperbaric oxygen

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