摘要
DistributionandaccumulationofNd,anditseffectonsecretionofprogesteroneinmicewerestudiedusingradioisotopetracer(147Nd)technique.Followingsingleintraperitonealadministrationofneodymiumtracedwith147Ndatadoseof200mg*kg-1,unevendistributionoftheradioactiveNdoccurredinvarioustissuesandorgans.Muchamountof147Ndaccumulatesinthebone,andtheresidueincreaseswiththelapseoftime.Someamountofradioactivitywasalsodetectedineyes,bloodandbrain,buttheaccumulationdecreasedwiththetimeduetoexcretionandre-distributioninmice.Incomparisonwithcontrols,concentrationofprogesteroneisfoundtobesignificantlylowerintheserumofadministeredmice,indicatingasignificantlyinhibitoryeffectofNdonsecretionofprogesterone.
出版日期
2004年02月12日(中国期刊网平台首次上网日期,不代表论文的发表时间)