慢性乙型肝炎拉米夫定治疗的疗效和药理研究

慢性乙型肝炎 拉米夫定 疗效 药理Clinical and pharmacological study on treatment of chronic hepatitis B with lamivudineAbstract Objective efficacy and pharmacological lamivudine treatment of chronic hepatitis B. Methods retrospective analysis of 120 cases of chronic hepatitis B patients bedivided into experimental group and control group with 60 cases in each group the experimental group with lamivudine treatment while the control group used conventional hepatoprotectivetherapy. Results comparing the two groups of patients before and after treatment of alanine aminotransferase changes significantly with statistical significance (P< 0.05) comparedtwo groups of patients a significant difference in the HBeAg negative conversion HBeAg/ conversion anti -HBe HBV-DNA changes before and after treatment there was statisticallysignificant (P< 0.05). Conclusion the treatment of chronic hepatitis B with lamivudine obvious effect is worthy to be popularized in clinical medicine.Keywords chronic hepatitis B Lam