摘要
摘要目的对急性双系列白血病诊断与预后进行探析.方法临床资料选自２０１１年１月至２０１５年６月我院资料的２２例急性双系列白血病患者,开展细胞遗传学、流式细胞仪细胞免疫分型等检测,以分析患者预后.结果２２例患者的CD３４检测均是阳性,２０例患者HLA－DR检测是阳性,２例患者是阴性.１６例患者为髓—B淋巴细胞混合占７２．７％,６例患者是髓—T淋巴细胞混合占２７．３％.治疗前,１４例患者开展骨髓细胞遗传学检查均正常.２２例患者在我院接受联合化疗,综合患者的髓系白血病、淋巴细胞,治疗完全缓解率是４５．５％,治疗总有效率是５４．５％.缓解持续时间平均是(９．８±２．２)个月,２例患者在诱导治疗过程中死亡.结论急性双系列白血病的临床诊断较为复杂,需要医务人员结合多种资料,以提高急性双系列白血病的临床诊断准确率,给予及时有效的治疗,提高患者的完全缓解率,延长患者的生存期.关键词急性双系列白血病;临床诊断;预后Abstractobjectivedoubleseriesofacuteleukemiadiagnosisandprognosisforanalysis．MethodstheclinicaldatafromJanuary２０１１toJune２０１５inourdatadoubleseriesof２２casesofacuteleukemiapatients,cellsincellgenetics,thecellularimmuneclassificationsuchastesting,toanalyzetheprognosisofpaＧtients．Results２２casesofCD３４testispositive,２０patientswithHLA－DRtestispositive,２patientswerenegative．１６patientsforpulp－BlymphocytemixＧture(７２．７％),６patientsispulp－Tlymphocytesmixedaccountedfor２７．３％．Beforethetreatment,thebonemarrowcytogeneticexaminationwasconductedfor１４patientswerenormal．２２patientsinourhospitaltoacceptchemotherapy,synthesisofpatientswithmyeloidleukemia,lymphocytes,treatmentofcompletereＧsponseratewas４５．５％,totaleffectiveratewas５４．５％．Easethedurationis(９．８＋２．２)monthsonaverage,２patientsdiedduringtheprocessofinductiontheraＧpy．Conclusiontheclinicaldiagnosisofdoubleseriesofacuteleukemiaisrelativelycomplex,needmedicalpersonnelincombinationwithavarietyofdata,inordertoimprovetheaccuracyofclinicaldiagnosisofdoubleseriesofacuteleukemia,givetimelyandeffectivetreatment,improvepatient＇scompleteresponserate,proＧlongthKeeypawtioerndts＇ssurvival．Acutedoubleseriesleukemia;Clinicaldiagnosis;Theprognosis中图分类号R４４６文献标识码B文章编号１００１－５３０２(２０１５)０９－０６５３－０２
出版日期
2015年09月19日（中国期刊网平台首次上网日期，不代表论文的发表时间）
