摘要
Adultstem/progenitorcellsplayimportantrolesintissuehomeostasisandhaveimportantimplicationsforregenerativemedicine.Itwasoncethoughtthatformationofnewbloodvesselsinadultonlyoccursthroughangiogenesis,aprocesswherebynewvesselsareformedfromexistingmatureendothelialcells;whilevasculogenesis,wherenewvesselsarederivedfromdifferentiationofendothelialprogenitorcells(EPCs),wasthoughttooccurexclusivelyinembryos.ThediscoveryofadultEPCsafewyearsagohaschangedthisoldparadigm;andsubsequentstudiesshowedthatEPCsmaybeapromisingtoolforthetreatmentofvasculardisorders.However,therehavebeenconflictingreportsonsubtypes,surfacemarkers,andfunctionsofEPCs;andthustheexactoriginandidentityofEPCsremaintobedefined.AcommonapproachtoobtainEPCsistoisolateandculturemononuclearcellsfromperipheralbloodandtoselectadherentcellsfor
出版日期
2006年06月16日(中国期刊网平台首次上网日期,不代表论文的发表时间)