摘要
【摘要】 目的 探讨不同时期加用胰岛素对妊娠合并糖尿病孕产妇妊娠结局的影响。方法 150例妊娠合并糖尿病孕产妇， 按照胰岛素不同给药时间分为前期组（孕 <32周， 80例）和后期组（孕≥ 32周， 70例） ;胰岛素服用方法和计量按照孕产妇个体情况而定 ;对两组血糖、妊娠并发症及新生儿并发症进行统计分析。结果 治疗后， 前期组孕产妇空腹血糖和餐后 2 h血糖分别为（ 5.31±0.61）、（ 7.16±0.84） mmol/L， 显著优于后期组的（ 5.82±0.52）、（ 7.77±0.91） mmol/L， 差异有统计学意义（ P<0.05）。治疗后， 前期组合并高血压、死产、产后出血及感染发生率均显著低于后期组， 剖宫产及早产发生率均显著高于后期组， 前期组各新生儿并发症发生率均显著低于后期组， 差异有统计学意义（ P<0.05）。结论 在孕 32周
前对妊娠合并糖尿病孕妇进行治疗可显著控制孕产妇血糖， 同时可显著改善妊娠并发症及新生儿并发症的发生情况 ;对妊娠合并糖尿病孕产妇应做到早发现， 早治疗。
【关键词】 妊娠合并糖尿病 ;胰岛素 ;给药时间 ;妊娠结局
[Abstract] Objective To investigate the effect of insulin on pregnancy outcome of pregnant women with diabetes mellitus. Methods 150 cases of pregnant women with diabetes mellitus were divided into two groups according to the different administration time of insulin: early group (80 cases < 32 weeks of gestation) and late stage group (70 cases of pregnancy ≥ 32 weeks); the method and measurement of insulin were determined according to the individual situation of pregnant women; the blood glucose, pregnancy complications and neonatal complications of the two groups were statistically analyzed. Results after treatment, the fasting blood glucose and 2 hours postprandial blood glucose in the early group were (5.31 ± 0.61), (7.16 ± 0.84) mmol / L, which were significantly better than those in the later group (5.82 ± 0.52), (7.77 ± 0.91) mmol / L, the difference was statistically significant (P < 0.05). After treatment, the incidence of hypertension, stillbirth, postpartum hemorrhage and infection in the early group was significantly lower than that in the later group, the incidence of cesarean section and premature delivery was significantly higher than that in the later group, and the incidence of complications in the early group was significantly lower than that in the later group (P < 0.05). Conclusion at 32 weeks of gestation
出版日期
2020年09月14日（中国期刊网平台首次上网日期，不代表论文的发表时间）
