摘要
摘要目的：探讨不同剂量丙种球蛋白联合阿司匹林治疗小儿川崎病的临床疗效分析。方法： 2018年 7月 -2019年 7月收治川崎病患儿 68例，从中随机抽取 34例为对照组，给予低剂量丙种球蛋白，抽取 34例为观察组，给予高剂量丙种球蛋白 ;同时两组患者均联合应用阿司匹林。给予临床随访调查，分析两组患儿经不同剂量丙种球蛋白治疗后，其临床症状改善状况及血清检测结果之间的差异，继而探讨不同剂量丙种球蛋白联合阿司匹林治疗应用于小儿川崎病中的临床价值。结果：观察组综合有效率显著高于对照组，临床症状改善时间及血清检测结果均显著优于对照组，差异有统计学意义（ P<0.f15）。结论：高剂量丙种球蛋白联合阿司匹林应用于川崎病的临床治疗过程中疗效显著，能够有效提升临床症状改善效率，抑制病情恶化，安全性高，值得推广。
关键词 小儿川崎病 ;丙种球蛋白 ;阿司匹林 ;应用价值
Objective: To investigate the clinical effect of different doses of gamma globulin combined with aspirin in the treatment of Kawasaki disease in children. Methods: from July 2018 to July 2019, 68 children with Kawasaki disease were treated. 34 of them were randomly selected as the control group, given low-dose gamma globulin, 34 as the observation group, given high-dose gamma globulin; at the same time, both groups were treated with aspirin. The clinical follow-up survey was conducted to analyze the difference of clinical symptoms and serum test results between the two groups after different doses of gamma globulin treatment, and then to explore the clinical value of different doses of gamma globulin combined with aspirin treatment in children with Kawasaki disease. Results: the comprehensive effective rate of the observation group was significantly higher than that of the control group, the improvement time of clinical symptoms and the results of serum test were significantly better than that of the control group (P < 0.f15). Conclusion: high dose of gamma globulin combined with aspirin is effective in the clinical treatment of Kawasaki disease. It can effectively improve the efficiency of clinical symptoms improvement, inhibit the deterioration of the disease, and has high safety. It is worth popularizing.
出版日期
2020年09月21日（中国期刊网平台首次上网日期，不代表论文的发表时间）
