the protective effects against noise trauma by sound conditioning in rats

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摘要 ObjectiveToinvestigatetheprotectiveeffectsofsoundconditioningagainstsubsequenthigh-levelnoisetraumainrats.MethodRatswereexposedtoa4kHzoctavebandnoiseat95dBSPLfor10hours,thentoatraumaticexposuredose(105dBSPLfor13hours)delivered12hlater.Controlanimalswereexposuredtothetraumaticdoseonly.ABRthresholdswereobtainedbeforeandafternoiseexposure.ResultAnimalsthathadbeensoundconditioneddemonstratedlessABRthresholdshiftcomparedtothosethathadnot.ConclusionModeratelevelsoundexposureappearstohaveatougheningeffectontheratcochlea(or'conditioning')leadingtodecreasedhearinglossfromsubsequenttraumaticexposure.
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出版日期 2009年01月11日(中国期刊网平台首次上网日期,不代表论文的发表时间)
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