Quantitative Determination of Adrenaline Hydrochloride Injection and Noradrenaline Bitartrate Injection by a New HPLC Method via Substitute for Reference Substance-中国期刊网

摘要 AnHPLCmethodforquantitativedeterminationofadrenalinehydrochlorideinjectionandnoradrenalinebitartrateinjectionwasestablishedandvalidatedwithasubstituteforthereferencesubstance.Phenylephrinehydrochloridewasselectedasthesubstituteforthereferencesubstanceofadrenalineandnoradrenalinebitartrate.Thecorrectionfactorofphenylephrinehydrochloridewithrespecttothereferencesubstanceofadrenalineandnoradrenalinebitartratewasdeterminedunderdefinedconditions.Adrenalinehydrochlorideinjectionandnoradrenalinebitartrateinjectionwerequantifiedbyassayingphenylephrinehydrochlorideandacorrectfactor.TheresultsindicatethattheHPLCmethodwiththesubstituteforreferencesubstancewasreliableandfeasibleforquantitativedeterminationofdrugs.

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Quantitative Determination of Adrenaline Hydrochloride Injection and Noradrenaline Bitartrate Injection by a New HPLC Method via Substitute for Reference Substance

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Quantitative Determination of Adrenaline Hydrochloride Injection and Noradrenaline Bitartrate Injection by a New HPLC Method via Substitute for Reference Substance

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