简介：摘要目的探讨院前溶栓与院内溶栓治疗急性心肌梗死的临床效果与安全性。方法选取60例急性心肌梗死患者，将患者随机分为院前溶栓组与院内溶栓组，各30例，观察对比两组患者的临床疗效及安全性。结果院前溶栓组患者的血管再通率明显高于院内溶栓组，再灌注心律失常发生率、出血率及病死率则低于院内溶栓组，组间比较差异有统计学意义（P＜0.05）。结论院前溶栓治疗能有效缩短发病至开始溶栓时间，并提高冠状动脉的再通率，降低心脏事件发生率与病死率，安全有效，值得在临床上推广应用。

简介：摘要目的探讨急性心肌梗死患者心肺复苏后采用溶栓治疗的临床疗效.方法选取６０例急性心肌梗死并发心跳骤停复苏成功患者,将其随机分为对照组与观察组,各３０例.两组均给予冠脉扩张或抗休克、抗心律失常及脑保护等对症治疗,观察组在此基础上给予尿激酶静脉溶栓治疗,观察对比两组患者的梗死血管再通率、病死率及出血率.结果观察组患者的梗死血管再通率明显高于对照组,未见死亡病例,较对照组差异显著(P均＜０．０５),从出血状况看,两组差异无统计学意义(P＞０．０５).结论急性心肌梗死患者心肺复苏后应用溶栓治疗效果显著,不仅能提高治疗效果,还能降低病死率与出血率,安全有效,值得在临床上推广应用.关键词急性心肌梗死;心肺复苏;溶栓治疗ClinicalanalysisofacutemyocardialinfarctionthrombolytictherapyaftercardiopulmonaryresuscitationTuShumin(emergencyinternalmedicinedeptofShangqiuFirstPeople’sHospital,HenanShangqiu４７６１００)AbstractobjectiveOnpatientswithacutemyocardialinfarctionaftercardiopulmonaryresuscitationwiththeclinicalefficacyofthrombolysistreatment．MethodsWeselected６０casesofacutemyocardialinfarctioncomplicatedwithcardiacarrestresuscitationofpatients,theywererandomlydividedintocontrolgroupandobservationgroup,３０casesineach．Thetwogroupsweregivencoronarydilationorantishock,antiarrhythmiaandbrainprotectionandothersymptomatictreatment,observationgroupwastreaＧtedonthebasisofintravenousthrombolytictherapywithurokinase,comparativeobservationoftwogroupsofpatientswithinfarctionvascularrecanalizationrate,mortalityrateandbleedingrate．ResultInfarctioninpatientswithvascularrecanalizationrateofobservationgroupwasobviouslyhigherthanthatofcontrolgroup,nodeathcase,comＧparedwiththecontrolgrouphadsignificantdifference(P＜０．０５),frombleedingcondition,withnosignificantdifferencebetweentwogroups(P＞０．０５)．ConclusionPatientswithcardiopulmonaryresuscitationinpatientswithacutemyocardialinfarctionafterthrombolytictreatmentapplicationeffectisremarkable,notonlycanimprovethetheraＧpeuticKefefyecwto,brdustalsocanreducethemortalityrateandbleedingrate,safeandeffective,andworthyofpopularizationandapplicationinclinic．Acutemyocardialinfarction;cardiopulmonaryresuscitation;thrombolytictherapy中图分类号R５４１文献标识码B文章编号１００８－６３１５(２０１５)１２－０１２４－０２