简介：【摘要】目的：比较眼底激光联合眼内注射雷珠单抗治疗糖尿病视网膜病变的疗效。方法：选取于2018年12月~2020年12月在我院的就诊的DR患者112例，随机均衡分为两组，每组56例，将眼底激光疗法给予对照组，观察组联合激光疗法、雷珠单抗展开治疗。对比组间疗效。记录并对比组间观察指标。结果：两组组间疗效对比，观察组（96.4%）优于对照组(73.2）,统计学数据研究具有意义（P

简介：摘要1例69岁男性患者因胃腺癌伴肝脏、胰腺及腹腔淋巴结转移，在完成奥沙利铂联合雷替曲赛化疗4个周期后，改用纳武利尤单抗联合替吉奥治疗。10 d后患者全身出现严重皮疹，考虑为纳武利尤单抗和替吉奥所致皮肤不良反应，停用2药，给予甲泼尼龙和抗过敏药物治疗。皮疹逐渐好转，糖皮质激素逐步减量至停药。但停药当日患者出现发热、寒战、严重呼吸衰竭，结合临床治疗情况、实验室检查结果及影像学改变，考虑为纳武利尤单抗所致免疫相关性肺炎。给予甲泼尼龙、抗感染、经鼻高流量氧疗等治疗，4 d后患者喘憋症状较前明显好转，28 d后复查CT肺部炎症较前明显好转。

简介：摘要目的探索短暂性脑缺血发作的药物治疗方案，研究氯吡格雷联合阿司匹林联合用药方案的临床应用效果。方法依据治疗方案的不同对80例患者进行分组，对照组40例实施单一阿司匹林用药方案，观察组40例实施氯吡格雷+阿司匹林联合用药方案，以临床疗效、凝血功能为观察指标对比两种用药方案的应用效果。结果经治疗后，观察组治疗总有效率显著高于对照组，且PT、APTT和FIB等凝血功能指标优于对照组，两组比较有显著性差异（P＜0.05）。结论对于短暂性脑缺血发作采用氯吡格雷+阿司匹林联合用药方案可作为首选方案之一。

简介：摘要 目的：探讨对脑血栓患者选择氯吡格雷 +疏血通注射液治疗后获得的临床效果以及治疗安全性。方法：收治脑血栓患者 50例，采用数字奇偶法分组。对照组 25例选择氯吡格雷进行治疗，观察组 25例选择氯吡格雷 +疏血通注射液进行治疗，最终就两组脑血栓患者用药效果、血流变指标以及用药安全性对比。结果：同对照组脑血栓患者用药效果（ 72.00%）对比，观察组总有效率（ 96.OO%）提升程度显著（ P<0.05） ;同对照组脑血栓患者血流变指标对比，观察组降低程度显著（ P<0.05） ;两组脑血栓患者均未呈现出明显用药反应。结论：医疗人员对于脑血栓患者选择氯吡格雷 +疏血通注射液加以治疗，其用药效果以及用药安全指数均有保障，并且可以将血流变指标显著改善，从而促进脑血栓患者病情康复。  　　关键词 疏血通注射液 ;氯吡格雷 ;脑血栓 ;临床效果 ;安全性  　 Objective: To explore the clinical effect and safety of clopidogrel + Shuxuetong injection in the treatment of cerebral thrombosis. Methods: 50 patients with cerebral thrombosis were divided into groups by digital parity. 25 cases in the control group were treated with clopidogrel, and 25 cases in the observation group were treated with clopidogrel + Shuxuetong injection. Finally, the therapeutic effect, hemorheology index and safety of the two groups were compared. Results: compared with the control group (72.00%), the total effective rate of the observation group (96.oo%) increased significantly (P < 0.05); compared with the control group, the hemorheology index of the observation group decreased significantly (P < 0.05); the two groups of cerebral thrombosis patients did not show significant drug response. Conclusion: clopidogrel + Shuxuetong injection is selected by medical staff for the treatment of cerebral thrombus patients, its medication effect and medication safety index are guaranteed, and the hemorheology index can be significantly improved, so as to promote the rehabilitation of cerebral thrombus patients.