简介: 【摘 要】目的:探讨特利加压素联合奥曲肽治疗肝硬化食管静脉曲张破裂出血患者临床疗效。方法:对本院收治的 60例肝硬化食管静脉曲张破裂出血患者进行观察,根据电脑随机的方式将之分为两组,即常规组( n=30)行奥曲肽治疗,研究组( n=30)行特利加压素联合奥曲肽治疗。结果:研究组止血时间显著短于常规组( p<0.05);研究组 12h止血率、 48h止血率均高于常规组( p<0.05);两组不良反应、再出血率对比无差异( p>0.05)。结论:在奥曲肽治疗的同时,联合特利加压素予以进一步治疗肝硬化食管静脉曲张破裂出血的效果更为突出,具有安全可靠、高效等优势,值得临床推广。 【关键词】 特利加压素;奥曲肽;肝硬化;食管静脉曲张破裂出血;疗效 [Abstract] Objective: To investigate the clinical effect of terlipressin combined with octreotide in the treatment of esophageal variceal bleeding patients with cirrhosis. Methods: 60 patients with esophageal variceal bleeding due to cirrhosis in our hospital were observed. They were randomly divided into two groups: the routine group (n = 30) treated with octreotide and the study group (n = 30) treated with terlipressin and octreotide. Results: the hemostasis time of the study group was significantly shorter than that of the routine group (P < 0.05); the hemostasis rate of the study group at 12h and 48h was higher than that of the routine group (P < 0.05); there was no difference in adverse reactions and rebleeding rate between the two groups (P > 0.05). Conclusion: at the same time of octreotide treatment, terlipressin combined with octreotide is more effective in the treatment of esophageal variceal bleeding in cirrhosis, which has the advantages of safety, reliability and high efficiency, and is worthy of clinical promotion.