简介:SincePresidentObamaannouncedthePrecisionMedicineInitiativeintheUnitedStates,moreandmoreattentionhasbeenpaidtoprecisionmedicine.However,clinicianshavealreadyusedittotreatconditionssuchascancer.Manycardiovasculardiseaseshaveafamilialpresentation,andgeneticvariantsareassociatedwiththeprevention,diagnosis,andtreatmentofcardiovasculardiseases,whicharethebasisforprovidingprecisecaretopatientswithcardiovasculardiseases.Large-scalecohortsandmultiomicsarecriticalcomponentsofprecisionmedicine.Herewesummarizetheapplicationofprecisionmedicinetocardiovasculardiseasesbasedoncohortandomicstudies,andhopetoelicitdiscussionaboutfuturehealthcare.
简介:Somehavesuggestedtheterm“Precision”medicinereplace“Personalized”medicine.Idon’tlikeeithertermandI’lltellyouwhy.WhatisPrecision?ThewordPrecisioncanbedefinedsimplyasreproducibilityanddoesnotnecessarilymeanthatthediagnosisisaccurate.Thus,ifthemedicaldecisionisprecisebutnotnecessarilyaccurateitisnotveryuseful.Accuracyisdefinedasbeingneartothetrueordesiredvalue.e.g.consideratargetonariflerange;iftheshotshaveatightgroupinganywhereonthetarget,theyareprecisebuttheyareonlypreciseandaccurateifthattightgroupingisintheBull’seye.
简介:Somediseasesotherthancardiacdiseasecanbe“prevented”,butthepurposeofthiscommunicationwrittenbyaclinicalcardiologist,notasapreventionspecialist,istofocusstrictlyoncardiovasculardisease.Thedefinitionofpreventivemedicineinsimplesttermsmeanskeepingyourpatienthealthy.Inadditiontomaintaininghealth,ofcourse,wewanttopreventthedisabilityassociatedwithcardiacdiseaseaswellasdeathintheyoungerperson.
简介:AreviewarticlebyHaoetal.(JAmCollCardiol2017;69(24):2952–66)hashadhugerepercussionsamongthosefamiliarwithtraditionalChinesemedicine(TCM)intheinternationalacademiccommunity.ItevaluatedtheefficacyandsafetyofTCMforcardiovasculardiseaseandthepharmacologicaleffectofactiveTCMingredientsonthecardiovascularsystemandpotentialmechanisms.Wehaveseveralcomments:Firstly,wegiveabriefsummaryaddressingnonpharmacotherapyinTCM,includingacupuncture,moxibustion,Qigong,andTaiChi.Secondly,wehaveaddedtraditionalantiarrhythmicdrug–relatedrandomizedcontrolledtrialstomakethecoveragemorecomprehensive.Lastly,wesupporttheconceptthatresearchinto,developmentof,andapplicationofactiveingredientsispartofmodernTCM.
简介:Complicationsaremorefrequentinelderlypatientswithcoronaryheartdisease(CHD),suchasimpairedglucosetoleranceandconstipations.Itisalwaysdifficulttocurethesecomplicationsinclinicalpractice.Inthiscasewehadsuccessfullycuredaneighty-threeyearsoldmanwithCHDcomplicatingimpairedglucosetoleranceandconstipationbyintegratedChinese-Westernmedicine.