简介：Researchdatashowedthatsyndromicapproachcouldsuccessfullymanagegonococcalandchlamydialinfectionsinmalesandsyphilisandchancroidinmalesandfemales.However,lowsensitivity,specificityandpositivepredictivevaluewerefoundinthesyndromicmanagementofvaginaldischarge.Itisrecommendedthatthesyndromicalgorithmformanagementofvaginaldischargeusedwhenservinghigh-riskandsymptomaticwomen.

简介：Objective:Tointroducethecurrentstatusofimplementingsexuallytransmittedinfection(STIs)syndromicmanagementinChina.Methods:Datawerecollectedandanalyzedfromtheliterature.Possiblesolutionsweresuggestedfortheobstaclesencounteredintheimplementationprocess.Results:Validationofrevisedflowchartsforthemanagementofthreesyndromes(urethritis,vaginaldischarge,andgenitalulcers)hasbeenconductedinChina.Thefeasibility,effectivenessandacceptanceofusingasyndromicSTIapproachwereinvestigatedinalargestudyinHainan,ZhejiangandHubeiProvinces.Chiefobstaclestoimplementationincludedthefollowing:lackofsupportfromgovernmentauthorities;negativereactionbyhospitals;lackofcriticalthinkingandinnovation;perceivedover-emphasisontreatmentattheexpenseofprevention;andlackofcoverageforseveralimportantpathogenswithintreatmentalgorithms.Possiblesolutionsmayincludepolicyadvocacy,adoptingsyndromicmanagementintoaChinesecontext,disseminationandpromotion,trainingofproviders,encouraginguseofsyndromicapproach,andconductingoperationalresearch.Conclusions:SyndromicSTImanagementprovidesafeasibleapproachforthediagnosisandtreatmentofSTIsinChina.Furthereffortsshouldbemadeforscalingupitsapplicationinclinicalsettings.

简介：Reiter'ssyndromeisasecondarydiseaseofurethrainfection.Itconsistsofurethritis,nonsuppurativearthritis,conjunctivitisandcutaneousmucosalesions.YoungmalesaremorelikelytogetReiter'ssyndromethanfemales.Thusfar,therearenoreportsofwomeninChinawithReiter'sSyndrome.ThisreportdocumentstwofemaleswithReiter'sSyndrome.

简介：临床资料患者,女,70岁。主因无症状外阴红斑2个月,于2015年6月9日就诊。2个月前无明显诱因,患者右侧大阴唇上方出现红斑,直径约2cm,无自觉不适。半个月前就诊于我科门诊,按湿疹给予曲安奈德益康唑乳膏外用10余天,皮损无好转。

简介：Summary:RiskfactorsforgenitourinaryChlamydiatrachomatis(Ct)infectionwereinvestigatedusinganSTDrelativeriskfactorquestionnaireamong176patientsandtheirregularsexualpartners.Twenty-fourindependentvariableswereselectedforanalysis,nineofwhichwereconfirmedasfactorsassociatedwithC.trachomatis.Fouroftheninefactorsweresignificantlycorrelatedtoinfectionusingamultifactorialunconditionallogisticregressionmodelwhichincluded:levelofeducation(oddsratios[ORs]:2.144forbelowjuniormiddleschool),numberofsexualpartners(ORs:4.503for≥5),numberofregularpartner'ssexualpartner(ORs:16.333for≥5),STDhistoryofregularpartner(ORs:18.417fortheirSTDhistory).Thesedatademonstratethatregularpartner'ssexualbehaviorsarealsoanimportantriskfactorforCtinfectionamong,STDclinicclients.

简介：目的：探讨卵巢高分化黏液性癌（highlydifferentiatedOvarianmucinouscarcinoma,HDOMC）患者中MMP-2、MMP-9、S100A14的表达水平及意义。方法：采用免疫组化法对40例正常卵巢组织、43例卵巢黏液性肿瘤（Ovarianmucinoustumor,OMT）、80例HDOMC患者中MMP-2、MMP-9、S100A14的表达水平进行检测,并分析HDOMC患者中S100A14表达与MMP-2、MMP-9表达的相关性。结果：MMP-2、MMP-9、S100A14在正常卵巢组织、OMT、HDOMC患者中的表达水平呈递增趋势,且两两组间比较差异显著（P〈0.05）。Spearman相关分析：HDOMC患者中S100A14表达与MMP-2、MMP-9表达水平两两呈正相关（P〈0.05）。MMP-2、MMP-9、S100A14表达水平与HDOMC患者手术-病理分期（FIGO）、CA-125水平有关（P〈0.05）;与年龄、肿瘤直径、淋巴结转移无关（P〉0.05）。结论：MMP-2、MMP-9、S100A14表达水平升高与HDOMC发生、进展、早期转移具有显著相关性,早期联合筛查这些指标对HDOMC病情演变及治疗预后评估具有重要价值。

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