简介:TheJournalofBionicsEngineeringaimstopublishhighqualityoriginalpapersontheimportantsubjectsofbionicengineeringandrelatedtopics.Itisaninternationalforumofhighqualityformultidisciplinarycommunicationsontopicswhichwillinclude:thefundamentalunderstandingofanimalsandplantsforbionicandbiomimeticengineering;mechanical,manufacturing,materials,chemical,medicalandagriculturalengineering;informationandcontroltechnology;constructionandmechanics;locomotion;design;textiletechnology;architecture,buildingdesignsandplanningofthebuiltenvironment;andsystemsintegrationrelatingdirectlytobionicsandbiomimetics.
简介:TheestablishmentmeetingofInternationalSocietyofBionicEngineering(ISBE)convenedgrandlyatZhuhai,ChinainSeptember14-16,2010.Relatedofficialsandrepresentativesattendedtheopeningceremony,whocamefromtheResearchCouncils,UK,theNationalNaturalScienceFoundationofAmerica,theBionicSocietyofGer-
简介:Exploringthehumanbrainisperhapsthemostchallengingandfascinatingscientificissueinthe21stcentury.Itwillfacilitatethedevelopmentofvariousaspectsofthesociety,includingeconomics,education,healthcare,nationaldefenseanddailylife.Theartificialintelligencetechniquesarebecomingusefulasanalternatemethodofclassicaltechniquesorasacomponentofanintegratedsystem.Theyareusedtosolvecomplicatedproblemsinvariousfieldsandbecomingincreasinglypopularnowadays.Especially,theinvestigationofhumanbrainwillpromotetheartificialintelligencetechniques,utilizingtheaccumulatingknowledgeofneuroscience,brain-machineinterfacetechniques,algorithmsofspikingneuralnetworksandneuromorphicsupercomputers.Consequently,weprovideacomprehensivesurveyoftheresearchandmotivationsforbrain-inspiredartificialintelligenceanditsengineeringoveritshistory.Thegoalsofthisworkaretoprovideabriefreviewoftheresearchassociatedwithbrain-inspiredartificialintelligenceanditsrelatedengineeringtechniques,andtomotivatefurtherworkbyelucidatingchallengesinthefieldwherenewresearchesarerequired.
简介:Overthepastdecades,cellsurfacecharge,althoughexperimentallyobserved,hasnotbeenwellunderstoodparticularlyfromtheviewpointofbiophysics.Ourrecentstudieshaveshownthatallcancercellsexhib让negativesurfacechargesthataredirectlyproportionaltothesecretedlacticacid,auniquecancermetaboliccharacteristic:highrateofglycolysis.Wehavethereforedesignedanddevelopedasetofelectrically-charged,fluorescent,andsuper-paramagneticnanoprobes,capableofsensitivedetectionofcancercellsbasedonthesurfacecharges.Theseprobesareutilizedtobindontocellsviaelectrostaticreactionforcaptureandmagneticseparation.Inthisfashion,weareabletocharacterizecellsurfacechargesthatareregulatedbydifferentmetabolicpatterns,thereforeeffectivelydistinguishingthecancercellsfromthenormalcells.All22cancercellsofdifferentorgansarefoundtobenegativelychargedthereforeboundstronglybythepositively-chargednanoprobes,whereasthenormalcellsshowinsignificantbindingtothenanoprobesofeitherchargesigns(positiveornegative).Thisfindingsuggeststhatalltestedcancercellsarenegatively-chargedandnormalcellsareeithercharge-neutralorslightlypositive.Fordiagnosis,cancercellscanbedetected,electrostaticallybound,andmagneticallyseparatedinbloodbychargedandsuper-paramagneticnanoprobes.Intherapeutics,circulatingcancercells(CTCs)canbefilteredandremovedinacontinuousfashiontoreducetheriskofcancermetastasis.Ifsuccessful,thisnewnanotechnologywillrevolutionizeearlycancerdiagnosisandpotentiallyenablenewtherapeuticsinclinicalsettings.