简介：WederivedrevisedeffectivediffusionenergybarriersfollowingtheBoltzmanndistributionassumptionforimpurityatomsinabulkmaterialundertheimpactofvariouskindsofpointdefectstorevealtheinsightsofmigrationmechanisms.Theeffectivediffusionenergybarriersofcopperimpuritiesinbulkzirconiumwerecalculatedthroughthefirstprinciplemethodunderthepresentedhypothesis.Ourresults(?E||=1.27eV,?E⊥=1.31eV)agreedwellwiththeexperimentalresults(?E||=1.54eV,?E⊥=1.60eV),whichvalidatedbulkdiffusionasthemajormechanismforcopperdiffusioninzirconium.Theeffectivediffusionenergybarrierscouldbeusedforestimatingwhetherthedefectswillacceleratethediffusionorslowthemdownbyactingastrapsoftheimpurityatoms.Ontheotherhand,thefirstprincipleresultsoftheimpuritydiffusionviadefectscouldbefurtherusedasinputsoflargerscalecomputationalsimulations,suchasMC(MonteCarlo)orPhaseFieldcalculations.

简介：Background:Preventinganteriorcruciateligament(ACL)injuriesisimportanttoavoidlong-termadversehealthconsequences.Identifyingbarrierstoimplementationofthesepreventionprogramsiscrucialtoreducingtheincidenceoftheseinjuries.OurpurposewastoidentifybarriersofimplementationforACLinjurypreventionprogramsandsuggestmechanismsforreducingthebarriersthroughapplicationofaSocioEcologicalModel(SEM).Methods:StudiesinvestigatingACLpreventionprogrameffectivenessweresearchedinMedlineviaPubMedandtheCochraneLibrary,andasubsequentreviewofthereferencesoftheidentifiedarticles,yielded15articlestotal.Inclusioncriteriaencompassedprospectivecontrolledtrials,publishedinEnglish,withACLinjuriesastheprimaryoutcome.Studieswereindependentlyappraisedby2reviewersformethodologicalqualityusingthePEDroscale.Barrierstoimplementationwereidentifiedwhenreportedinatleast2separatestudies.ASEMwasusedtosuggestwaystoreducetheidentifiedbarriers.Results:Fivebarrierswereidentified:motivation,timerequirements,skillrequirementsforprogramfacilitators,compliance,andcost.TheSEMsuggestedwaystominimizethebarriersatalllevelsofthemodelfromtheindividualthroughpolicylevels.Conclusion:IdentificationofbarrierstoprogramimplementationandsuggestinghowtoreducethemthroughtheSEMisacriticalfirststeptowardenablingACLpreventionprogramstobemoreeffectiveandultimatelyreducingtheincidenceoftheseinjuries.