简介：心若明镜，心似琉璃.干净清澈的比喻，可以让人觉得一切都很纯粹、不染尘埃。人心变的透明这是一个美好的、用文学渲染出的愿望。尘世是复杂的，人心是多变的,也许正是因为这些我们才去把玩那些透明绚丽的东西．才会赞美简单、纯真。

简介：TheDigoxinInvestigationGrouptrialhasmultipleflawsinthetrialdesignforthefindingstobeuniversallyapplicable.Digoxininlowserumconcentrations(0.5-0.9ng/mL)hasbeenshowntodecreasemortalityinheartfailurepatients.Multipletrialsindifferentpatientpopulationsalsoshowbenefitofdigoxininheartfailurepatients,includingwomen,elderlypatients,renaldiseasepatients,andpatientswithheartfailurewithpreservedejectionfraction.Retrospectiveobservationaldatalinkingdigoxinusefortreatmentofatrialfibrillationtoincreasedmortalityisnotseeninsubgroupsofrandomizedcontrolledtrialsorpopulationregistries.Digoxinremainsausefuldruginthetoolboxofphysiciansdealingwithheartfailurepatients.

简介：Bridgepressureflowscouratclearwaterthresholdconditionisstudiedtheoreticallyandexperimentally.Theflumeexperimentsrevealthatthemeasuredscourprofilesunderabridgearemoreorless2-dimensional;allthemeasuredscourprofilescanbedescribedbytwosimilarityequations,wherethehorizontaldistanceisscaledbythedeckwidthwhilethelocalscourbythemaximumscourdepth;themaximumscourpositionislocatedjustunderthebridgeabout15%deckwidthfromthedownstreamdeckedge;thescourbeginsataboutonedeckwidthupstreamthebridgewhilethedepositionoccursatabout2.5deckwidthsdownstreamthebridge;andthemaximumscourdepthdecreaseswithincreas-ingsedimentsize,butincreaseswithdeckinundation.Thetheoreticalanalysisshowsthat:bridgescourcanbedividedintothreecases,i.e.downstreamunsubmerged,partiallysubmerged,andtotallysubmerged.Fordownstreamunsubmergedflows,themaximumbridgescourdepthisanopen-channelproblemwheretheconventionalmethodsintermsofcriticalvelocityorbedshearstresscanbeapplied;forpartiallyandtotallysubmergedflows,theequilibriummaximumscourdepthcanbedescribedbyascourandaninundationsimilaritynumber,whichhasbeenconfirmedbyexperimentswithtwodecksandtwosedimentsizes.Forapplication,adesignandfieldevaluationprocedurewithexamplesispresented,includingthemaximumscourdepthandscourprofile.

简介：The?ngstr?mturbiditycoefficient(β)andLinketurbidityfactor(T_L)areusedtostudytheatmosphericconditionsinWuhan,CentralChina,usingmeasureddirectsolarradiationduring2010–2011inthisstudy.Theresultsshowthatannualmeanβvaluesgenerallyincreasefrom0.28inthemorningto0.35atnoon,andthendecreaseto0.1inthelateafternoonduringtheday;annualmeanT_Lgenerallyvariesfrom3to7inCentralChina.Bothturbiditycoefficientshavemaximumvaluesinspringandsummer,whileminimumvaluesareobservedinwintermonths.Italsorevealsthatβvaluesshowpreponderance(52.8%)between0.15and0.35,78.1%ofT_Lvaluesarebetween3.3and7.7,whichcanbecomparedwithothersitesaroundtheworld.Relationshipbetweenturbiditycoefficientsandmainmeteorologicalparameters(humidity,temperatureandwinddirection)havebeenfurtherinvestigated,itisdiscoveredthatthelocalaerosolconcentrations,dusteventsinnorthernChinaandSouthwestMonsoonfromtheIndianOceaninfluencestheβvaluesinthestudyarea.

简介：AIM:Todescribetheresultsof5consecutivecasesofclearlensextractioninangleclosurepatientsforthetreatmentofelevatedintraocularpressure(IOP).·METHODS:Retrospectiveobservationalcaseseries.Allangleclosurepatientswereontwoormoretopicalglaucomamedicationsandhadpriorlaseriridotomy.Eyesunderwentclearlensextractionbyphacoemu-lsificationwithintraocularlensimplantation.·RESULTS:Allfivepatientsinthiscaseseriescarriedthediagnosisofangle-closureglaucomaandhaduncontrolledIOPpriortosurgerydespitetopicalmedications.AfterclearlensextractionthreeofthecaseshadgoodIOPcontrol(IOP<22mmHg)withouttheneedfortopicalmedications.InonecasetheIOPwasbettercontrolledaftersurgery,however,topicalmedicationswererequired.ThedesiredIOPwasnotmetinonecasedespiterestartingmaximumtopicaltherapy.·CONCLUSION:Thiscaseseriessuggeststhattheremaybearolefortherapeuticclearlensextractioninselectcasesofangle-closureglaucoma.

简介：ShockwavesofJapan'smassive2011earthquakearestillstrainingthenervesoftheJapanesepeopletoday.Inconfrontingnationalcrisis,thenationhasbeenforcedtofundamentallyquestionthedevelopmentpaththattheywillfollowinthefuture.

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简介：美国国防部2004年1月批准了一种称之为“All-Clear”的新型化学生物洗消泡沫的使用。这种洗消泡沫是在缓冲蛋白质中的一种水解酶与生物杀灭剂的混合物。它能解决遭受化学和生物袭击的军事、工业和农业目标的大面积地域的快速消毒问题。

简介：美国科利尔通讯公司（Clear．Com）作为内通领导厂商，在今年的展会上，除了以往的主流产品外．又新增了两款新品。Clear—Com中国区首席代表吴琼先生介绍．无线产品领域．最高端的FreeSpeak今年推出了更新换代产品FreeSpeaklln其主机没有发生大的变化，但进行了软件升级。

简介：AbstractBackground:Circular RNA ciRS-7 has been reported to be involved in the progression of various cancers. However, ciRS-7 expression and its role in clear cell renal cell carcinoma (ccRCC) progression remains unclear. This study aimed to investigate the effect of ciRS-7 expression on ccRCC and the related signaling pathway.Methods:ciRS-7 expression was analyzed using quantitative reverse transcription polymerase chain reaction in 87 pairs of ccRCC and matched adjacent normal tissues. The role of ciRS-7 in ccRCC cell proliferation and invasion was determined using the cell counting kit-8 and invasion assays, respectively. Potential mechanisms underlying the role of ciRS-7 in promoting ccRCC progression were explored by Western blotting. The relationship between the expression of ciRS-7 and features of ccRCC was analyzed by the Chi-square test and progression-free survival was determined using a Kaplan-Meier plot.Results:ciRS-7 was overexpressed in ccRCC tissues compared with that in matched adjacent normal tissues. In addition, ciRS-7 up-regulation was closely associated with tumor diameter (P = 0.050), clinical stage (P = 0.009), and distant metastasis (P = 0.007). ciRS-7 knockdown in 786O and 769P cells markedly inhibited their proliferative and invasive abilities. In addition, ciRS-7 inhibition reduced phosphorylated epidermal growth factor receptor (p-EGFR) and phosphorylated serine/threonine kinase (p-Akt) levels.Conclusions:ciRS-7 up-regulation could promote ccRCC cell proliferation and invasion, which may be related with the EGFR/Akt signaling pathway. ciRS-7 might be a potential ccRCC therapeutic target.

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简介：Objective:MemorystemTcells(Tscm)haveattractedattentionbecauseoftheirenhancedself-renewal,multipotentcapacity,andanti-tumorcapacities.However,littleisknownaboutTscminpatientswithrenalclearcellcarcinoma(RCC)andtheroleofWntsignalinginthesecells.WeevaluatedTscmfromRCCpatientsconcerningtheiractivationofWntsignalinginvitroandexploredthemechanismofpreferentialsurvival.Methods:FlowcytometryidentifiedsurfacemarkersandcytokinesproducedfromaccumulatedTscminthepresenceoftheglycogensynthasekinasebetainhibitorTWS119.Apoptosiswasevaluatedafterinductionusingtumornecrosisfactor-alpha.ImmunofluorescenceandWesternblotanalyseswereusedtoinvestigatetheactivationofthenuclearfactor-kappaB(NF-КB)pathway.Results:RCCpatientshadasimilarpercentageofCD4~+andCD8~+Tscmashealthydonors.ActivationofWntsignalingbyTWS119resultedintheaccumulationofTscminactivatedTcells,butreversalofdifferentiatedTcellstoTscmwasnotachieved.PreferentialsurvivalofTscmwasassociatedwithincreasedanti-apoptoticabilitymediateddownstreamoftheNF-КBactivationpathway.Conclusions:ThefindingthatTscmcanaccumulatebyWntsignalinginvitroinbloodfromRCCpatientswillhelpindevisingnewcancertherapystrategiesofTscm-basedadoptiveimmunotherapy,suchasdendriticcell-stimulatedTscm,andTcellreceptororchimericantigenreceptor-engineeredTscm.

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简介：InthisstudytheQingweatherrecords"ClearandRainRecords"wereusedtoreconstructthe18thcenturysummer(June-August)precipitationandmonthlyprecipitationseriesofMay,June,July,andAugust.Thenatureoftheserecordsandthetechniqucoftransformingthemintonumericalcodesaredescribed.Theprocedureofconvertingthesedescriptiverecordsintoquantitativemonthlyprecipitationanditsscientificbasisaregivenindetail.Thereliabilityoftheobtaindprecipitationseriesisalsoex-amined.

简介：ClearOne公司介绍ClearOne公司是一家专门为各级组织提供音频、视频和网络会议产品的通讯公司。1983年成立，总部位于美国犹他州盐湖城。ClearOne进入中国已十多年，在行业内处于低调高效的品牌，ClearOne最近一直在做一些内部的调整。今年ClearOne有一个比较强势的市场回归，并带来新的合作伙伴；

简介：ObservationoftheoperationoftheSanmenxiaReservoirontheYellowRiverhasledtotheconclusionthattopreserveacertaineffectivestoragevolumeforreservoirsbuiltonheavilysilt-ladenriversisfeasibleifthereservoirisoperatedaccordingtotheprincipleknownas"storingtheclearwateranddischargingthemuddyflow".Therelativestabilityofthebedelevationattheendofthebackwaterandthereservoir'serosionanddepositionequilibriumdependonthecompatibilityofthepoollevelmaintainedinnon-floodseasonswiththeconditionsofflowandsedimentloadduringfloodseasons.OperatingthereservoirtoregulatethefloodandsedimentloadduringfloodseasonscanreducetherateofaggradationintheLowerYellowRiver.Thebasicconditionforapplyingtheoperationmodeof"storingtheclearwateranddischargingthemuddyflow"isthatasufficientamountofwatershouldbeusedfordischargingsedimentduringfloodseasons.Undertheconditionofextremelylowflowyears,reservoirsedimentationcannotbeavoidedevenifthisoperationmodeisadopted.

简介：在由有单个time/dual隧道裂口窗户算法的GMS-5/VISSR热红外线的数据的这份报纸的检索结果揭示特征日报、季节几代表性的陆地表面的清楚天空的陆地表面温度(LST)的变化录入中国包括Tarim盆，Qinghai西藏的高原，Hunshandake沙，诺思中国平原，并且华南。在上面的区域的清楚天空的LST的季节的变化由太阳的放射为影响的不同表面反照率，土壤水内容，和程度清楚地变化。每月的一般水准日报LST的范围在一年里有二座山峰和二条山谷。在东亚和在台湾海峡和黄海的南方的海表面温度(SST)的大多数土地的LST的特征也作为比较被分析。Tarim盆和Hunshandake沙有可观的LST不仅日报周期而且显著季节的变化。在2000，最大的每月的一般水准日报在两个区域的LST的范围在Hunshadake沙活动范围是超过30K，和年度范围58.50K。在Qinghai西藏的高原的LST的季节的变化是在东亚，Tarim盆，和Hunshandake沙的不到那些。然而，最大值日报范围在这个区域存在。每年的一般水准日报范围是在在2000的Qinghai西藏的高原的28.05K。特征日报、季节、年度从1998～2000的变化也在这研究被显示出。所有结果将对为陆地表面类型的变化的气候变化，放射平衡，和评价的研究珍贵。[出版摘要]

简介：在空气的顶的放射预算在气候研究起一个关键作用。比作宽带流动，幽灵似地解决的出去的longwave放射或流动(OLR)，与在不同乐队的富有的大气的信息，在GCM的评估有明显的优点。不同于需要辅助大小和信息的方法，这里，我们拿大气红外线更健全(表情)观察作为一个例子当模特儿由尖分布造一个前後一致的算法(ADM)，完全基于发光观察，在热带海洋上估计清楚天空的幽灵似地解决的流动。作为为如此的ADM的关键步骤，景色类型评价在选择表情隧道从发光和亮度温度被获得。然后，宽带OLR象一样合成光谱流动被导出由光谱ADM并且使用合成系列和谷神星验证(云和地球绚烂的精力系统)观察。处于大多数状况，之间的吝啬的OLR差别光谱ADM产品和CERES观察在钫?以内??醰顣鱎???????？？

简介：1月20日,香港西九龙文化戏曲中心正式启用,Clear-Com作为唯一指定品牌,为戏曲中心提供IP化内通解决方案。为保证现场演出的效果,戏曲中心配置了Eclipse-HX-Median矩阵及HMS-4X基站等系列内通产品,尤其在矩阵中采用了新发布的E-IPA-64和E-Dante-HX板卡,取得了很好的测试效果。其中E-IPA-64卡通过IP方式把无线腰包和矩阵和面板连接起来,而E-Dante-HX卡则是和现有调音台通过IPDante连接起来,最后HelixNet则用传统4线连接矩阵,再用IP方式把有线腰包连接起來。