简介：ThetranswellchambermigrationassayandCCDdigitalcameraimagingtechniqueswereusedtoinvestigatetherelationshipbetweenregulatoryvolumedecrease(RVD)andcellmigrationinnasopharyngealcarcinomacells(CNE-2Zcells).Bothmigratedandnon-migratedCNE-2Zcells,whenswollenby47%hypotonicsolution,exhibitedRVDwhichwasinhibitedbyextracellularapplicationofchloridechannelblockersadenosine5'-triphosphate(ATP),5-nitro-2-(3-phenylpropylamino)benzoicacid(NPPB)andtamoxifen.However,RVDrateinmigratedCNE-2Zcellswasbiggerthanthatofnon-migratedcellsandthesensitivityofmigratedcellstoNPPBandtamoxifenwashigherthanthatofnonmigratedcells.ATP,NPPBandtamoxifenalsoinhibitedmigrationofCNE-2Zcells.TheinhibitionofmigrationwaspositivelycorrelatedtotheblockageofRVD,withacorrelationcoefficient(r)=0.99,suggestingafunctionalrelationshipbetweenRVDandcellmigration.WeconcludethatRVDisinvolvedincellmigrationandRVDmayplayanimportantroleinmigratoryprocessinCNE-2Zcells.

简介：Thehigh-powerlaserbeaminthefinalopticsassemblyofhigh-powerlaserfacilitiesisoftenmodulatedbycontaminationparticles,whichmaycauselocalhighlightintensity,therebyincreasingthefilamentarydamageprobabilityforopticalcomponents.Tostudythegeneraldesignbasisforafinalopticsassemblytodecreasetheriskoffilamentarydamage,different-sizedcontaminationparticlesdepositedonacomponentsurfacearesimulatedtomodulatea351-nmlaserbeambasedontheopticaltransmissiontheory,andthecorrespondingsimulationresultsareanalyzedstatisticallyintermsofthepropagationcharacteristicandthelightfieldintensitydistributionofthemodulatedlaserbeam.Thestatisticalresultsshowthatcomponentthicknessanddistancebetweencomponentscantosomeextentbeoptimizedtoreducetheappearanceoflocalhighlightintensity,andthegeneraldesignbasisofcomponentthicknessandarrangementaregivenfordifferentcontrollevelsofparticlesizes.Moreover,thestatisticalresultscanalsopredictthelaserbeamqualityapproximatelyundertheexistingopticsdesignandenvironmentalcleanliness.Theoptimizeddesignforfinalopticsassemblybasedonenvironmentalcleanlinesslevelisusefultoprolongthelifetimeofopticsandenhancetheoutputpowerofhigh-powerlaserfacilities.

简介：Ashocktubeisusedtoinvestigatethebubbledynamicsundersuddendecreaseofambientpressure.Boththeoscillatingandmonotonouslygrowingbubblesweresimultaneouslyobserved.TheoreticalapproachisbasedontheRayleigh-PlessetandHerring'sequationsforincompressibleandcompressibleliquids,respectively.Consideringthelinearapproximationoftheseequationsforthequasiequilibriumstate,twocriticalWebernumbersaredefined.Theyenableonetopredictthefollowingmodesofthebubbleexpansion:(i)unboundedgrowth,(ii)asymptoticgrowthtolimitedvolumeand(iii)attenuatedoscillations,dependingonthepressureforce,viscosityandcompressibilityoftheliquid.

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简介：模式获得光谱被Fourier系列扩大方法forInAs/GaAs量点(QD)测量有在不同注射水流的QD的七栈的激光。有特殊山峰的Gainspectra在大约1210nmand1300nm的短、长的波长被观察。为有1060亩m的洞长度的QD激光，长波长的山峰获得首先慢慢地增加或甚至快速作为短波长度增加的山峰获得与注射水流减少，并且当注射水流进一步增加，最后在接近浸透的价值前快速增加。

简介：摘要ObjectiveTo evaluate the effectiveness of radial extracorporeal shock wave therapy on ankle flexor spasticity in stroke survivors and to reveal changes in the fibroelastic components of muscle.DesignRandomized controlled trial.SettingInpatient neuro-rehabilitation clinic of a university hospital.ParticipantsStroke patients with ankle flexor spasticity.InterventionsPatients were randomized to three groups; radial extracorporeal shock wave therapy, sham, or control. Active and sham therapy were administered two sessions/week for two weeks. All patients received conventional rehabilitation.Main measuresThe primary outcome was Modified Ashworth Scale. Secondary outcomes were the Tardieu Scale and elastic properties of plantar flexor muscles assessed by elastography (strain index). All assessments were performed before, immediately after the treatment, and four weeks later at follow-up.ResultsFifty-one participants were enrolled (active therapy n＝17, sham n＝17, control n＝17). Modified Ashworth scores showed a significant decrease in the active therapy group (from 2.47±0.72 to 1.41±0.62) compared to sham (from 2.19±1.05 to 2.06±1.12) and control (from 2.06±0.85 to 2.00±0.73) groups immediately after the treatment (P<0.001). Tardieu results were also in concordance (P<0.001), however this effect was not preserved at follow-up. Elastic properties of the ankle flexors were improved in all groups at both assessments after the therapy showing significant decreases in strain index (P<0.001). However, there was no difference among the groups in terms of improvement in elastography.ConclusionRadial extracorporeal shock wave therapy has short-term anti-spastic effects on ankle flexor muscles when used as an adjunct to conventional rehabilitation.

简介：DuringJuneandJuly2003,JingmenPetrochemicalCompanycardedoutthecommercialtestontechnologyforhigh-temperaturecrackingofC5fractiontodecreaseolefincontentofgasolineinDCCU.ThetestresultsshowedthattheolefincontentofDCCgasolinehaddecreasedfrom68.32m%to42.5m%,meanwhilethepropyleneyieldincreasedby0.90m%.

简介：牙槽的巨噬细胞(AMs)由释放许多cytokines和煽动性的调停人在肺的纤维变性的致病起一个关键作用，这被表明了。另外，反常信号变换器和在AMs的激活可以玩的transcription-1(STAT1)的使活跃之物在齿槽炎和肺的纤维变性的进程的一个枢轴的角色。在这研究，我们transfectedSTAT1antisenseoligodeoxynucleotide(ASON)进由aerosolization的老鼠，然后与导致的bleomycin(BLM)从老鼠在bronchoalveolarlavage液体(BALF)在象TGF-，PDGF和TNF-那样的煽动性的调停人上调查了STAT1ASON的效果老鼠肺的纤维变性。我们的结果证明由aerosolization的STAT1ASON能进入肺纸巾和AMs。STAT1ASON能与肺的纤维变性在老鼠的AMs禁止mRNA和STAT1和ICAM-1的蛋白质表情，并且没在肝和肾上有有毒的副作用。AerosolizedSTAT1ASON能改善通过在导致BLM的老鼠禁止煽动性的调停人的分泌物的齿槽炎肺的纤维变性。这些结果建议aerosolizedSTAT1ASON可能在肺的纤维变性的处理被看作有希望的新策略。

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简介：通过对比考察REDUCE、DECREASE和LESSEN三个具有'减少'意义的同义词在英国国家语料库(BNC)和中国学习者英语语料库(CLEC)中的搭配行为和语义韵差异,探讨英语本族语者与中国英语学习者对该组同义词的使用规律。研究表明:三个节点词各有其典型搭配特征和语义韵倾向;英语学习者对该组同义词的掌握存在诸多不足之处,尤其对DECREASE的用法存在很大误解,在LESSEN的搭配行为上出现了明显偏差;同义词混用倾向和母语干扰是影响英语学习者掌握该组同义词的主要因素。