简介:WiththegrowingofdigitizeddatatransformingonInternet,theissuesofinformationsecurity,dataprivacy,andforensicanalysishavebecomemoreandmoreattracted.Researchershaveprovidedsolutionsforproblemsinthefield.Theobjectiveofthisspecialissueistopresentresearchanddevelopmentactivitiesinthevariousaspects.Afteraverycarefulreview,theeditorialcommitteeaccepted8highquality
简介:ThisSpecialSectiononLanguageandCognitionofJournalofElectronicScienceandTechnology(JEST)presentsacollectiveofstate-of-theartinterdisciplinaryresearchonlanguageandcognition.Itfeaturesempiricalandtheoreticalstudiesoncognitiveapproachestolanguage,usingavarietyofmethodologicalapproaches,frombehavioralmeasurestoneuroimaging.Thetopicsdiscussedarevaried,rangingfromlanguagecomprehensionandacquisitiontothelanguage-emotioninteractions,reflectingmarkedbroadeningoftheresearchagendainthisfield.Weinviteyetmoreintegratedresearchtomovethefieldforward.
简介:Digitaltransformationgenerallyreferstotheprocessofchangeinbusinessandsociety,basedontheomnipresenceofsensors,networks,information,andcommunicationtechnology.Evershorterdevelopmentandinnovationcyclesareacharacteristicfeatureofthisprocess,whichiscurrentlyinfluencingallindustriesandallareasoflife,beitindustrialproduction,trade,transport,healthcare,oreducation.Theubiquityofdigitaltechnologyleadstoprofoundpolitical,economic,andsocialchanges,butalsotomultifacetedinnovations.
简介:为了成功地感染,招待房间并且躲避主机免疫者反应,一个类型III分泌物系统(T3SS)被伤寒通常使用细菌的病原体象enteropathogenicEscherichiacoli(EPEC)那样。最近的调查结果表明了各种各样的受动器通过T3SS被注入主人房间并且在煽动性的发信号的小径上施加禁止的效果,破坏对这些病原体的有免疫力的回答。这里,我们考察针对探讨EPEC受动器蛋白质调制的几条重要煽动性的发信号小径的调整的最近的研究,例如原子factor-B(NF-B)和激活mitogen的蛋白质kinase(MAPK)小径,它在这块未经勘探的地和帮助里提供卓见进未完成的工作为EPEC受动器在煽动性的发信号的网络识别新奇位置。
简介:TheroleofthetranscriptionfactorNF-κBinshapingthecancermicroenvironmentisbecomingincreasinglyclear.InflammationalterstheactivityofenzymesthatmodulateNF-κBfunction,andcausesextensivechangesingenomicchromatinthatultimatelydrasticallyaltercell-specificgeneexpression.NF-κBregulatestheexpressionofcytokinesandadhesionfactorsthatcontrolinteractionsamongadjacentcells.Assuch,NF-κBfinetunestissuecellularcomposition,aswellastissues'interactionswiththeimmunesystem.Therefore,NF-κBchangesthecellresponsetohormonesandtocontactwithneighboringcells.ActivatingNF-κBconferstranscriptionalandphenotypicplasticitytoacellandtherebyenablesprofoundlocalchangesintissuefunctionandcomposition.ResearchsuggeststhattheregulationofNF-κBtargetgenesisspecificallyalteredincancer.SuchalterationsoccurnotonlyduetomutationsofNF-κBregulatoryproteins,butalsobecauseofchangesintheactivityofspecificproteostaticmodulesandmetabolicpathways.ThisarticledescribesthemolecularmodeofNF-κBregulationwithafewcharacteristicexamplesoftargetgenes.
简介:Inthisstudy,weinvestigatetheinfluenceofdopingonthechargetransferanddevicecharacteristicsparametersinthebulkheterojunctionsolarcellsbasedonpoly(3-hexylthiophene)(P3HT)andamethanofuUerenederivative(PCBM).Organicsemiconductorsarealsoknowntobenotpureandtheyhavedefectsandimpurities,someofthemarebeingchargedandactasp-typeorn-typedopants.Calculationsofthesolarcellcharacteristicsparametersversusthep-dopinglevelhavebeendoneatthreedifferentn-dopings(N_d)thatconsistof5×10~(17)cm~(-3),10~(18)cm~(-3),and5×10~(18)cm~(-3).Weperformtheanalysisofthedopingconcentrationthroughthedrift-diffusionmodel,andcalculatethecurrentandvoltagedopingdependency.Wefindthatatthreedifferentn-dopantlevels,optimump-typedopingisaboutN_p=6×10~(18)cm~(-3).Simulationresultshaveshownthatbyincreasingdopinglevel,V_(oc)monotonicallyincreasesbydoping.CellefficiencyreachesitsmaximumatsomewhathigherdopingasFFhasitspeakatN_p=3×10~(18)cm~(-3).Moreover,thispaperdemonstratesthattheoptimumvalueforthep-dopingisaboutN_p=6×10~(18)cm~(-3)andoptimumvalueforn-dopantisN_d=10~(18)cm~(-3),respectively.Thesimulatedresultsconfirmthatdopingconsiderablyaffectstheperformanceoforganicsolarcells.
简介:从古巴的蝎子Rhopalurusjunceus表示昆虫选择的神经毒素(RjAa17f)的recombinantHelicoverpaarmigeranucleopolyhedrovirus(HearNPV)被用红相应再结合系统代替UDP-glucosyltransferase基因(egt)构造。另一egt删除了控制HearNPV被把egfp基因插入到egt地点以一个类似的方法构造。一步舞病毒的生长曲线和病毒的DNA复制曲线分析证实再结合没在宿主细胞影响病毒的生长和DNA复制。在在RjAa17f-HearNPV,Egfp-HearNPV和HZ8-HearNPV之间的吸藏身体形态发生没有可辨别的差别,它被传播电子显微镜学分析证实。然而,RjAa17f-HearNPV的杀虫的活动对第三中间形态H被提高。armigera幼虫根据毒力比较上的生物鉴定。在中部的致命的剂量有戏剧的减小(56.9%)(LD50)并且另外在中部的幸存时间的减小(13.4%)(为与HZ8-HearNPV相比的recombinantRjAa17f-HearNPV的圣50),但是当Egfp-HearNPV与HZ8-HearNPV相比时,仅仅在LD50的27.5%减小和在圣50的10.1%减小珍视。每日的食谱消费分析证明RjAa17f-HearNPV能禁止减HearNPV与egt相比喂的感染的幼虫。这些结果证明这新奇recombinantRjAa17f-HearNPV能对它的主人昆虫改进杀虫的效果,RjAa17f能是另外的recombinantbaculovirus构造的一个可观的候选人。