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简介：用水星的市场销售及服务部门的副董事长西思克·科第亚的话说，就是“水星对西班牙市场来说是很特别的一个存在，它给人以聪慧而又成熟的感觉，相当有竞争力”，福特公司为了获取西班牙用户的欢心，2006款水星MilanVoga便顺利诞生。

简介：The34theditionofMostraConvegnoExpocomfort-theinternationalbiennialexhibitiondedicatedtoheating,airconditioning,refrigeration,plumbingtechnology,watertreatmentandbathroomfittings-hasclosedwithextraordinarysuccess,especiallyfromthepointofviewofinternationalexposure.Witharound150,000visitors,26,282(18%)fromoverseas,theexhibitionwhichcametoanendon6thMarch2004beatallrecords.

简介：<正>一场闹剧结束之后,上赛季意甲联赛冠军终于归国际米兰所有,用国际米兰俱乐部主席法切蒂的话说:"这座奖杯是对正直的奖赏。如今意大利足球正在决心肃清不良风气,因此这座奖杯的到来具有双重意义。"我们应该为国际米兰这支团结的球队祝贺,这是该队在等待了17年以后,终于实现了自己的意甲冠军梦想。这是国际米兰队历史上第14次意甲冠军。对于欧洲人来说,"13"是个不吉利的数字,国际米兰恰恰被这道坎儿卡住了,迈过这道坎儿国际米兰用了整整17年。现在魔咒终于结束了,国际米兰的众球星们应该感到庆幸。国际米兰的这个联赛冠军来之不易,自莫拉蒂1995年入主国际米兰俱乐部以来,就一直在为获得一座意甲冠军奖

简介：摘要The rapid evolution of the health emergency linked to the spread of severe acute respiratory syndrome coronavirus 2 requires specifications for the rehabilitative management of patients with coronavirus disease 2019 (COVID-19). The symptomatic evolution of patients with COVID-19 is characterized by 2 phases: an acute phase in which respiratory symptoms prevail and a postacute phase in which patients can show symptoms related to prolonged immobilization, to previous and current respiratory dysfunctions, and to cognitive and emotional disorders. Thus, there is the need for specialized rehabilitative care for these patients. This communication reports the experience of the San Raffaele Hospital of Milan and recommends the setup of specialized clinical pathways for the rehabilitation of patients with COVID-19. In this hospital, between February 1 and March 2, 2020, about 50 patients were admitted every day with COVID-19 symptoms. In those days, about 400 acute care beds were created (intensive care/infectious diseases). In the following 30 days, from March 2 to mid-April, despite the presence of 60 daily arrivals to the emergency department, the organization of patient flow between different wards was modified, and several different units were created based on a more accurate integration of patients′ needs. According to this new organization, patients were admitted first to acute care COVID-19 units and then to COVID-19 rehabilitation units, post-COVID-19 rehabilitation units, and/or quarantine/observation units. After hospital discharge, telemedicine was used to follow-up with patients at home. Such clinical pathways should each involve dedicated multidisciplinary teams composed of pulmonologists, physiatrists, neurologists, cardiologists, physiotherapists, neuropsychologists, occupational therapists, speech therapists, and nutritionists.

简介：AbstractBackground:Hepatectomy for hepatocellular carcinoma (HCC) beyond the Milan criteria is shown to be beneficial. However, a high rate of post-operative HCC recurrence hinders the long-term survival of the patients. This study aimed to investigate and compare the impacts of tenofovir (TDF) and entecavir (ETV) on the recurrence of hepatitis B viral (HBV)-related HCC beyond the Milan criteria.Methods:Data pertaining to 1532 patients who underwent hepatectomy and received antiviral therapy between January 2014 and January 2019 were collected from five centers. Recurrence-free survival (RFS) analysis was performed using the Kaplan-Meier method. Cox proportional hazards regression analysis was performed to determine prognostic factors for HCC recurrence.Results:The analysis incorporates 595 HBV-related HCC patients. The overall 5-year RFS was 21.3%. Among them, 533 and 62 patients received ETV and TDF treatment, respectively. The 1-, 3-, and 5-year RFS rates were 46.3%, 27.4%, and 19.6%, respectively, in the ETV group compared with 65.1%, 41.8%, and 37.2%, respectively, in the TDF group (P < 0.001). Multivariate analysis showed that TDF treatment (hazard ratio [HR]: 0.604, P = 0.005), cirrhosis (HR: 1.557, P = 0.004), tumor size (HR: 1.037, P = 0.008), microvascular invasion (MVI) (HR: 1.403, P = 0.002), portal vein tumor thrombus (PVTT) (HR: 1.358, P = 0.012), capsular invasion (HR: 1.228, P= 0.040), and creatinine levels (CREA) (HR: 0.993, P = 0.031) were statistically significant prognostic factors associated with RFS.Conclusions:Patients with HCC beyond the Milan criteria exhibited a high rate of HCC recurrence after hepatectomy. Compared to the ETV therapy, TDF administration significantly lowered the risk of HCC recurrence.