简介:—Thepresentstudyinvestigatestheinteractionofsteepwaveswithsemi-circularbreakwaterwiththecomplexplane'sCauchyboundaryintegraltheorem.Theboundaryintegralmethodisusedtotransformthecalculationinfluiddomainintoitsboundaryalone.Inthecalculationthecomputationdo-mainismovedwiththepropagationofwaves.AnumericalsolutionisobtainedforincidentStokeswavespassingthesubmergedobstacles.Thismethodhasbeenextendedtothecalculationofwaverun-uponaslopeforestimatingwaveovertopping.
简介:—Theresultsofdesignandexperimentofasubmergedsemi-circularbreakwaterattheYangtzeestuaryshowthatthesubmergedstructurewillbeunsafewhenthegeneralempiricalwaveforceformulaforsemi-circularbreakwaterisusedindesign.Therefore,anewcalculationmethodforthewaveforcesact-ingonasubmergedsemi-circularstructureisgiveninthispaper,inwhichthewaveforceactingonthein-sidecircumferenceofsemi-circulararchisincluded,andthephasemodificationcoefficientinthegeneralempiricalformulaisadjustedaswell.Thenewwaveforcecalculationmethodhasbeenverifiedbythere-sultsofsevenrelatedphysicalmodeltestsandadoptedinthedesignofthesouthesturaryjettyofthefirststageprojectofDeepChannelImprovementProjectoftheYangtzeRiverEstuary,thetotaljettylengthbe-ing17.5km.
简介:Thispaperpresentsaclosed-formsolutionfordiffractionofplaneSHwavesbyasemi-circularcavityinhalf-spacebyusingwavefunctionexpansionmethod.Accuracyofthesolutionischeckedbythedisplacementresidualandstressresidualalongtheboundaries.Numericalresultsshowthattherearenotabledifferencesforresponseamplitudesbetweenasemi-circularcavityandawhole-circularcavityinahalf-space.
简介:Aradialcrackemanatingfromasemi-circularnotchisofsignificantengineeringimportance.Accuratedeterminationofkeyfracturemechanicsparametersisessentialfordamagetolerancedesignandfatiguecrackgrowthlifepredictions.Thepurposeofthispaperistoprovideanefficientandaccurateclosed-formweightfunctionapproachtothecalculationofcracksurfacedisplacementsforaradialcrackemanatingfromasemi-circularnotchinasemi-infiniteplate.Resultsarepresentedfortwoloadconditions:remoteappliedstressanduniformstresssegmentappliedtocracksurfaces.Basedonacorrectionofstressintensityfactorratio,highlyaccurateanalyticalequationsofcracksurfacedisplacementsunderthetwoloadconditionsaredevelopedbyfittingthedataobtainedwiththeweightfunctionmethod.ItisdemonstratedthattheWuCarlssonclosed-formweightfunctionsareveryefficient,accurateandeasy-to-useforcalculatingcracksurfacedisplacementsforarbitraryloadconditions.Themethodwillfacilitatefatiguecrackclosureandotherfracturemechanicsanalyseswhereaccuratecracksurfacedisplacementsarerequired.
简介:Theearth’ssurfaceirregularitiescansubstantiallyaffectseismicwavesandinduceamplificationsofgroundmotions.Thisstudyinvestigateswhetherandhowthesourcecharacteristicsaffectthesiteamplificationeffects.Ananalyticalmodelofalinesourceofcylindricalwavesimpingingonanalluvialvalleyisproposedtolinkthesourceandsite.Theanalyticalsolutiontothisproblemprovesoneaspectofthestrongeffectofsourceonsiteamplification,i.e.,thewavecurvatureeffect.Itisfoundthatthesiteamplificationdependsonthesourcelocation,especiallyunderconditionsofasmallsource-to-sitedistance.Whetherthedisplacementisamplifiedorreducedandthesizeoftheamplificationorreductionmaybedeterminedbythelocationofthesource.Itissuggestedthattraditionalstudiesofsiteresponses,whichusuallyignorethesourceeffect,shouldbefurtherimprovedbycombiningthesourcewithsiteeffects.
简介:Basedontheextendedhomogeneouscapacityhighprecisionintegrationmethodandthespectrummethodofvirtualboundarywithacomplexradiusvector,anovelsemi-analyticalmethod,whichhassatisfactorycomputationeffectivenessandprecision,ispresentedforsolvingtheacousticradiationfromasubmergedinfinitenon-circularcylindricalshellstiffenedbylongitudinalribsbymeansoftheFourierintegraltransformationandstationaryphasemethod.Inthiswork,besidesthenormalinteractingforce,whichiscommonlyadoptedbysomeresearchers,theotherinteractingforcesandmomentsbetweenthelongitudinalribsandthenon-circularcylindricalshellareconsideredatthesametime.Theeffectsofthenumberandthesizeofthecross-sectionoflongitudinalribsonthecharacteristicsofacousticradiationareinvestigated.NumericalresultsshowthatthemethodproposedismoreefficientthantheexistingmixedFE-BEmethod.
简介:AnanalyticalsolutionforscatteringofincidentSHwavesbyacircular-archillwithaconcentriccirculartunnelwasderivedbyFourier-Besselseriesexpansionandauxiliaryfunctionstechnique.Thesolutionisreducedtosolvingasetofinfinitelinearalgebraicequationsfinally.Theaccuraciesofthenumericalresultsarecheckedbytheresidualerrorsofboundaryconditionswiththetruncationorderincreasing.Thenumericalresultsshowthattheexistenceanddimensionofthetunnelhavegreateffectonmotionofthegroundsurfacenearbyanddynamicstressconcentrationofthetunnel.
简介:AsanewlydiscoveredtypeofRNA,circularRNAs(circRNAs)arewidespreadthroughouttheeukaryoticgenome.TheexpressionofcircRNAsisregulatedbybothcis-elementsandtrans-factors,andtheexpressionpatternofcircRNAsiscelltype-anddiseasespecific.Similartoothertypesofnon-codingRNAs,functionsofcircRNAsarealsoversatile.CircRNAshavebeenreportedpreviouslytofunctionasmicroRNA(miRNA)sponges,proteinsponges,codingRNAsorscaffoldsforproteincomplexes.Recently,severalcircRNAshavebeenreportedtoplayimportantrolesinhumanmalignancies,includingglioma.Here,wereviewedseveralreportsrelatedtocircRNAsandglioma,aswellasthepotentialdiagnosticandtherapeuticapplicationsofcircRNAsinbraincancer.Ingeneral,somecircRNAs,suchascircSMARCA5andcircCFH,arefoundtobeexpressedinagliomaspecificpattern,thesecircRNAsmaybeusedastumorbiomarkers.Inaddition,somecircRNAshavebeenfoundtoplayoncogenicrolesinglioma(e.g.,circNFIXandcircNT5E),whereasothershavebeenreportedtofunctionastumorsuppressors(e.g.,circFBXW7andcircSHPRH).Furthermore,circRNAisagoodtoolforproteinexpressionbecauseofitshigherstabilitycomparedtolinearRNAs.Thus,circRNAsmayalsobeanidealchoiceforgene/proteindeliveryinfuturebraincancertherapies.TherearesomechallengesincircRNAresearchingliomaandotherdiseases.ResearchrelatedtocircRNAsingliomaiscomparativelynewandmanymysteriesremaintobesolved.
简介:AbstractGastric cancer (GC) is a common malignancy and is the third leading cause of cancer-related death. At present, there is no simple and effective screening method for early-stage GC, and the treatment results and prognosis are poor. With the continuous improvement of molecular biology techniques, research on circular RNA (circRNA) has gradually expanded over time. Much data supports the role of circRNA in tumorigenesis. Moreover, due to its structural specificity and biological stability, circRNA is anticipated to be a potential biomarker for tumor diagnosis. Studies have confirmed that circRNA can participate in the proliferation, invasion, metastasis, and apoptosis of GC. These findings will lead to novel directions for the diagnosis and treatment of GC. This article reviews the structure and function of circRNA, summarizes the current studies on circRNA, and discusses the potential diagnostic value of circRNA in GC.
简介:Circulareconomy(CE)hasbeenputforwardasanimportantenvironmentalandresourcestrategyinChina.Aimingatthehighutilizationrateofresourcesandreductionofpollutants,CEmeanstorealizeashiftoffundamentalparadigm.Withthemodeofproductionandconsumptionfromlineartorecyclingmodel,thepromotionrequirestransdisciplinaryresearcheswhichintegratetechnological,ecological,social-culturalandothersciences.Thepresentstudyfocusesontheimplementationofcirculareconomyfromaninstitutionalperspective.Institutionactsasacrucialfactorbyprovidingincentivesfortechnicalinnovation,leadinginvestmentorientationanddeterminingpolicyeffectiveness,etc.Thispapermainlydiscussesabout:firstly,thefeatureofinstitution,institutionalchangesandinstitutionalinnovationisarticulated,togetherwitheco-industrialparkstrategy,extendedproducer’sresponsibilityanddematerializationprincipleasinnovativeinstitutionalarrangements;secondly,aspolicyplaysgreatroleoninstitutionalchangingprocess,themechanismofpolicyimplementationisneededtoberelated;asaresult,coevolutionofinstitutionsandpoliciesisthuspresented;atlast,apilotattemptismadetofindoutsomeoperationalavenuesinaccomplishmentofCEthroughboththeoreticalandpracticalmethodology,specialresolutionsareputforwardaftersomeprojectingdifficultiesanddilem-masinChinaaredescribed.
简介:Thispaperproposesacircularthresholdquantumsecretsharing(TQSS)schemewithpolarizedsinglephotons.Apolarizedsinglephotonsequencerunscircularlyamonganytormoreofnpartiesandanytormoreofnpartiescanreconstructthesecretkeywhentheycollaborate.Itshowsthatentanglementisnotnecessaryforquantumsecretsharing.Moreover,thetheoreticefficiencyisimprovedtoapproach100%asthesinglephotonscarryingthesecretkeyaredeterministicallyforwardedamonganytormoreofnparties,andeachphotoncancarryonebitofinformationwithoutquantumstorage.Thisprotocolisfeasiblewithcurrenttechnology.
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简介:Itisdifficulttorealizethetransformationfromtradi-tionaleconomyindustrialsystemtocirculareconomyindustrialsystem.Regardingprimaryrawmaterialsastheindicators,theindustrialsystemhasbeenspecifiedaccordingtothedivergenceamongtheindicatorsandthecircularutilizationmodes.Incom-parisonwiththeassociationamongindustrialsystems,therela-tionshipamongindustrialsub-systemsisnamedasindustrialcross-linkinginthispaper.Theindustrialsystemwhichcouldcompletelyutilizeandrecycletheindicatorsshouldbeincreasedandstrengthened,andthecirculareconomyindustrialsystemwithcompleteindustrialassociationandindustrialcross-linkingshouldalsobeconstructed.Takingthedevelopmentofcircularagricul-turalsystembasingonthetraditionalagriculturalsystemasanexample,thetraditionalagriculturalproductsareregardedastheindicatorswhichhavebeendividedintofoodstuffandcropstrawswhichareusedtoproducefoodandarticlesforuse,likefertilizer,energyandpapersetc.Thewaytoconstructthecircularagricul-turalindustrialsystemistoincreasetheindustrialsystemsthatcouldutilizetheproductsgeneratedfromcropstraws,fecesandothercastoffsandtransformthewastewaterandothertrucksintoenvironmentalfriendlyproducts.Ithasalsobeenpointedoutthattheconstructionofcirculareconomyindustrialsystemiscondu-civetothefoundationofcircularindustrialeconomicsandtheestablishmentoftheconstructionlayoutofcirculareconomyandtheapplicationschemes.Suggestionstothetheoreticalandprac-ticalworkofthenextstephavealsobeenbroughtforwardinthispaper.
简介:Ecologicaleconomicsandsustainabledevelopmenteconomicsarethebasictheoriestoresearchoncirculareconomy.Throughthesystemicallyresearchontherelationshipofthethreeabove,thispaperthinksthatthereuseandrecycleofcirculareconomyisawaythatthestallismendedafterasheepislost.Althoughthereductiontechnicallycontrolstheproductionprocess,itcannotsolvethewastecausedbyblindproductionandexcesscompetition.Wehaveexperiencedvarietyobstacleswhenimplementingthecirculareconomy,whosemainreasonistheconflictbetweentheindividualrationandthesocialration.Therefore,onlywhentheindividualrationandsocialrationinclinetoconformity,thecooperatingNashequilibriumwillbeappeared.Inordertorealizetheharmonyofecology,economyandsociety,wehavetoexploreeffectiveevaluationtheory.Thispapercitesthe'fiveflowsofwealthoperationtheory'fromprofessorMaChuandongtosearchoperationmechanismofcirculareconomy,makesclearthedevelopingthoughtsofcirculareconomybasedontherealities,andbringsforwardsomecountermeasurestodevelopcirculareconomybasedontheabovetheoreticalanalysis.
简介:Theanalysisofthedataofmodeltestsoftwolargedeepwharvesandmonographicexperimentalstudiesshowthattwoaspectsaretobeimprovedsoastopredictthewaveupliftforcesonthebottomofacircularcylinder.Thefirstaspectistheupliftpressuredistributiononthebottom,andthesecondisthecorrectdeterminationofthephaseformaximumhorizontalwaveforces.Thesecondproblemhasbeensolved.Synthesizingtheresultsoftheoreticalanalysisandexperiments,wesuggestadiagramforthedeterminationofthephasewhenthemaximumhorizontalwaveforceappears.Onthebasis-efthediagramthesimultaneouswaveupliftforcescanbeobtainedforthestructuralstabilityanalysis.
简介:NUMERICAL SIMULATION OF DISCONTINUOUS FLOW IN CIRCULAR CONDUITSNUMERICALSIMULATIONOFDISCONTINUOUSFLOWINCIRCULARCONDUITS¥MaoZe...