简介:Obstructivesleepapnoea(OSA)isacommonconditioncharacterizedbyrepetitiveepisodesofpartialorcompleteupperairwayobstructionduringsleep(Figure1).Obstructiveeventsareusuallyassociatedwithhypoxia,whichcanbeprofound,andterminatedbyanarousalfromsleep,producingsympatheticnervoussystemactivationandsleepfragmentationwith
简介:Wespendaboutone-thirdofourlivesasleep.Thismaysoundlikealotoftime,butitisnotwasted.我们一生中有三分之一的时间在睡觉,这听起来可能是很多时间,但是这些时间并没有浪费。Ourbodiesneedsleeptostayhealthy.Notgettingenoughsleep,oraswesometimessayshut-eye,canmakeussick.我们的身体需要睡眠才能保持健康。缺乏充足的睡眠会让我们生病。
简介:AbstractTreatment-emergent central sleep apnea (TECSA) is a specific form of sleep-disordered breathing, characterized by the emergence or persistence of central apneas during treatment for obstructive sleep apnea. The purpose of this review was to summarize the definition, epidemiology, potential mechanisms, clinical characteristics, and treatment of TECSA. We searched for relevant articles up to January 31, 2020, in the PubMed database. The prevalence of TECSA varied widely in different studies. The potential mechanisms leading to TECSA included ventilatory control instability, low arousal threshold, activation of lung stretch receptors, and prolonged circulation time. TECSA may be a self-limited disorder in some patients and could be resolved spontaneously over time with ongoing treatment of continuous positive airway pressure (CPAP). However, central apneas persist even with the regular CPAP therapy in some patients, and new treatment approaches such as adaptive servo-ventilation may be necessary. We concluded that several questions regarding TECSA remain, despite the findings of many studies, and it is necessary to carry out large surveys with basic scientific design and clinical trials for TECSA to clarify these irregularities. Further, it will be vital to evaluate the baseline demographic and polysomnographic data of TECSA patients more carefully and comprehensively.
简介:Background:Depressiondisordercoexistsinchronicdiseaseswithsomaticdiseasesandhashighmorbidity,disabilityandmortality.Currentresearcheshaveconfirmedthatdepressionmaybecausedbycoronaryheartdisease,hypertensionandheartfailure.Meanwhile,cardiovasculardiseasesmaycauseorworsendepression,leadingtoprolongedhospitalizationandcomplications.
简介:<正>SometimesIsleeplikeababyandsometimesIsleeplikealog.Forme,thebabyaspectisdefinedbyaseriesofinterruptionswithaquickfixinthebathroomorasnackfromthefridge.Thelogismorelikeastiffnessaccompaniedbyametaphoricchainsawbuzzfrommyapparentlyloudsnoring.Insomnia,habitualsleeplessness,fortunatelyisnotafriendofmine,butthat’sbecauseIhaveexperimentedwithdifferentwaystomakemyfortywinkslonger,wakenwithanattitudetoseizethedayandnotfeeltiredanhourafterbreakfast.Areyouoneoftheestimatedonehalfofthepopulationwhosuffersfromnotenoughshut-eye?Allowmetoletyouin
简介:我们由与多分数维的detrended变化分析方法分析可伸缩的行为在睡觉学习心率可变性(HRV)的动态性质。那心率被自治神经系统的二个分支的相互作用调整,是众所周知的:副交感、同情的神经系统。由调查multifractalproperties深,点亮rapid-eye-movement(雷姆)睡觉并且弄醒舞台,我们第一在可以被扩充同情的活动相对非雷姆睡觉引起的雷姆睡觉期间发现增加多分数维的行为。另外,在有第二顺序detrended变化分析的睡觉的远程的关联ofHRV的调查介绍不规则的现象。Thesefindings可能是有用的在醒来睡觉转变期间由自治神经系统理解心率的内在的调整机制。
简介:Studiesonbrain-evokedpotentialandcontingentnegativevariation(CNV)inmooddisorderremaincontroversial.Todate,noCNVdifferencebetweenunipolarandbipolardepressionhasbeenreported.Brain-evokedpotentialsweremeasuredinthepresentstudytoanalyzeCNVinthreesubtypesofmooddisorder(mania,unipolardepression,andbipolardepression),andtheseresultswerecomparedwithnormalcontrols.Inthemaniagroup,CNVamplitudeBwasgreaterthanincontrols,andthedepressiongroupexhibitedlowerCNVamplitudeBandsmallerA-S'2area,andprolongedpost-imperativenegativevariationlatency.TheCNVcomparisonbetweenunipolarandbipolardepressionfoundthattheprolongedpost-imperativenegativevariationlatencywasonlyinunipolardepression.Theseresultssuggestthatprolongedpost-imperativenegativevariationlatencyisacharacteristicofunipolardepression,andCNVamplitudechangeisastatecharacteristicofmooddisorderpatients.