简介：TielingValveGroupSpecialValveCo.,Ltd,formerlycalledExportFactoryoftheTielingValveWorks,TielingValveWorkswasestablishedin1935,oneofleadingenterprisesoftheMinistryofMachinery&IndustryoftheNationwithahistoryofmorethaneightyyearsandhasbeenfamousformanufacturingoflowpressureandlargesizevalves.In1997,theWorkswasreformedandtheExportFactorywasco-

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简介：BackgroundThisarticlesummarizedtheexperienceofatrioventricularvalvereplacementoperationforfunctionalsingleventriclepatientswhoseatrioventricularvalvewasinsufficiency.Thefollow-uptimeofoperationwasarrangedfromearly-tomedium-term.MethodsFromJuly2009toJuly2015,therewere40patientsoffunctionalsingleventriclereceivingtheoperationofatrioventricularvalvereplacement,including23maleand17femalepatients.TheageatA-Vvalvereplacementwasrangedfrom6daysto32years(themediumageof9years),andthebodyweightrangedfrom2.7to57kg(themediumbodyweightof21.5kg).Moreover,theatrioventricularvalvereplacementwasperformedonallpatientsunderextracorporealcirculation.ResultsAtrioventricularvalvereplacementwasperformedon40patientswithfunctionsingleventricleinhospital,ofwhicheight(20.0%)diedinhospitalincludingtwoneonateandinfant(agerange:6days-2yearsold)accountingfor25%(2/8),Amongthem,sevenpatientsdiedoflowcardiacoutputsyndrometwopatientswithrepeatedhypoxemiaconcurrentinfectionafteroperation,andonewithbilateraldiaphragmaticparalysisandmalignantarrhythmia.Forthepatientssufferingthesevereperivalvularleakage,therewasareoperation,andthecardiacfunctionbeforethefirstoperationwasclassⅣ.OnepatientreceivedhearttransplantationfinallyforsevereheartfailureafterAVvalvereplacement.Fortherestofpatients,theircardiacfunctionrecoveredtoclassⅠ-Ⅱafteroperation.ConclusionsForfunctionsingleventriclepatientswithatrioventricularvalveregurgitation,themortalityrateofatrioventricularvalvereplacementcanbeacceptediftheoperationwasindicated.Forpatientswithsevereatrioventricularvalueregurgitation,theresultoftheoperationintheearlyandmediumtermwassatisfying.Thus,theatrioventricularvalvereplacementservedasausefultreatmentforpatientsdiagnosedofA-Vvalveregurgitationandfunctionalsingleventricle.

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简介：Thedeveloppercutaneoustreatmentsformitralregurgitation(MR)havebeenbasedonestablishedsurgicalprocedures.Mostarebasedinsomewayonmitralannuloplasty.IndirectangioplastyutilizingcoronarysinusandleafletrepairwiththeMitraClipdevicehavethemostdevelopmentandclinicalapplication.Morerecently,afterthesuccessoftranscatheteraorticvalvereplacement,transcathetermitralvalvereplacementhasemerged.Acriticalunansweredquestioniswhattherelativerolesofvalverepairandvalvereplacementwillbe.ThelargestexperienceinpracticeiswithMitraClipleafletrepair.Theevidencebaseforthedevelopmentofthesenoveltherapiesincludessomedatainsurgicalcandidates,andregistrystudiesthathavebeendonepredominantlyinhighriskpopulations.

简介：Traumatictricuspidvalveinsufficiency(TTVI)isarelativelyuncommondisease.

简介：AbstractBackground:The past decade has witnessed an ever-increasing momentum of transcatheter aortic valve replacement (TAVR) and a subsequent paradigm shift in the contemporary management of severe aortic stenosis (AS). We conducted a multi-centric TAVR registry based on Chinese patients (the China Aortic valve tRanscatheter Replacement registrY [CARRY]) to delineate the clinical characteristics and outcomes of Chinese patients who underwent TAVR and compare the results between different valve types in different Chinese regions.Methods:CARRY is an all-comer registry of aortic valve disease patients undergoing TAVR across China and was designed as an observational study that retrospectively included all TAVR patients at each participating site. Seven hospitals in China participated in the CARRY, and 1204 patients from April 2012 to November 2020 were included. Categorical variables were compared using the chi-squared test, and continuous variables were analyzed using a t test or analysis of variance (ANOVA) test. The Kaplan-Meier curve was used to estimate the risk of adverse events during follow-up.Results:The mean age of the patients was 73.8 ± 6.5 years and 57.2% were male. The median Society of Thoracic Surgeon-Predicted Risk of Mortality score was 6.0 (3.7-8.9). Regarding the aortic valve, the proportion of bicuspid aortic valve (BAV) was 48.5%. During the hospital stay, the stroke rate was 0.7%, and the incidence of high-degree atrioventricular block indicating permanent pacemaker implantation was 11.0%. The in-hospital all-cause mortality rate was 2.2%. After 1 year, the overall mortality rate was 4.5%. Compared to patients with tricuspid aortic valve (TAV), those with BAV had similar in-hospital complication rates, but a lower incidence of in-hospital mortality (1.4% vs. 3.3%) and 1 year mortality (2.3% vs. 5.8%).Conclusions:TAVR candidates in China were younger, higher proportion of BAV, and had lower rates of post-procedural complications and mortality than other international all-comer registries. Given the use of early generation valves in the majority of the population, patients with BAV had similar rates of complications, but lower mortality than those with TAV. These findings further propel the extension of TAVR in low-risk patients.Trial Registration:https://www.chictr.org.cn/(No. ChiCTR2000038526).

简介：一条狭窄的隧道或裂缝的开发由于就在早朝的库下面尖隧道被报导了有用在批评的头条件以外在头承受增加。另外，最大的裂缝长度被强调了直到基础宽度的一半。由就裂缝而言开发批评的头的一个模型，批评的头能仅仅在某些条件下面与裂缝长度的发展增加，这被发现。尖失败数据的分析显示就裂缝长度而言的批评的头表情为批评的头组成一个潜在地有用的模型。

简介：现在的学习试图在差错地区揭示postseismic液体压力的恢复时期，提供进地震复发的卓见。数字建模基于2D被执行在地震差错以内模仿液体活动的简单分层的差错阀门模型。为了表明postseismic液体的特征，处于自然状态迫使，构造运动的干扰没被考虑。postseismic液体压力的恢复时期包括一个suddenchanging时期和一个长得多的波动时期。当模特儿的结果证明那差错渗透和孔是敏感参数并且与在地震差错地区的液体压力的恢复时期相对地成正比。当渗透从10把-15归结为10-18m2,时，恢复时期correspondently从400～2000年增加。上面、更低的液体压力被阀门封口分开，引起他们在相反的趋势的变化。

简介：ＡＮＥＷＬＹＤＵＰＬＩＣＡＴＯＲＦＯＲＰＵＬＳＡＴＩＬＥＡＮＤＳＴＥＡＤＹＦＬＯＷＴＥＳＴＩＮＧＯＦＡＲＴＩＦＩＣＩＡＬＨＥＡＲＴＶＡＬＶＥＡＮＥＷＬＹＤＵＰＬＩＣＡＴＯＲＦＯＲＰＵＬＳＡＴＩＬＥＡＮＤＳＴＥＡＤＹＦＬＯＷＴＥＳＴＩＮＧＯＦＡＲＴＩＦ...

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简介：Tetralogyoffallot(TOF)occursinapproximately1in5000livebirthsandaccountsfor12%-14%ofcon-genitalheartdisease.Surgicalrepairwasfirstintroducedinthe1950sandthereisnowalargepopulationofadultswithrepairedTOF.

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简介：这研究试图观察pyrolytic碳bileaflet的耐久性机械阀门prosthesis.The机械阀门修复术被阀门prosthesis.Then的耐久性测试仪器在vivo在vitro测试，植入的阀门的耐久性与动物实验和临床的application.In被观察为5min的影响测试和3.8亿的耐久性测试在vitro骑车，没有观察的flyer，穿孔和骨折的现象，以及不穿或基于th的坑

简介：AbstractBackground:Postoperative pneumonia (POP) is one of the most common infections following heart valve surgery (HVS) and is associated with a significant increase in morbidity, mortality, and health care costs. This study aimed to identify the major risk factors associated with the occurrence of POP following HVS and to derive and validate a clinical risk score.Methods:Adults undergoing open HVS between January 2016 and December 2019 at a single institution were enrolled in this study. Patients were randomly assigned to the derivation and validation sets at 1:1 ratio. A prediction model was developed with multivariable logistic regression analysis in the derivation set. Points were assigned to independent risk factors based on their regression coefficients.Results:POP occurred in 316 of the 3853 patients (8.2%). Multivariable analysis identified ten significant predictors for POP in the derivation set, including older age, smoking history, chronic obstructive pulmonary disease, diabetes mellitus, renal insufficiency, poor cardiac function, heart surgery history, longer cardiopulmonary bypass, blood transfusion, and concomitant coronary and/or aortic surgery. A 22-point risk score based on the multivariable model was then generated, demonstrating good discrimination (C-statistic: 0.81), and calibration (Hosmer-Lemeshow χ2 = 8.234, P = 0.312). The prediction rule also showed adequate discriminative power (C-statistic: 0.83) and calibration (Hosmer-Lemeshow χ2 = 5.606, P = 0.691) in the validation set. Three risk intervals were defined as low-, medium-, and high-risk groups.Conclusion:We derived and validated a 22-point risk score for POP following HVS, which may be useful in preventive interventions and risk management.Trial Registration:Chictr.org, ChiCTR1900028127; http://www.chictr.org.cn/showproj.aspx?proj=46932

简介：AIM:ToevaluatetheoutcomesofAhmedglaucomavalve(AGV)implantationsurgeryforrefractoryglaucoma.METHODS:Thisone-armedhistoricalcohortstudywasconductedin2011.Refractoryglaucomawasdefinedaseyeswithanintraocularpressure(IOP)greaterthan21mmHgwithmaximallytoleratedglaucomamedications,failedsurgeries,orboth.ForalleyeswithrefractoryglaucomathatunderwentAGVimplantation,datawerecollectedonIOP,thebestcorrectedvisualacuity(BCVA)andglaucomamedicationspreoperativelyand4,6,12,24and56wkpostoperatively.LogarithmvaluesofIOPwerecalculatedandcompared.RESULTS:Thestudygroupwascomprisedof30patients(30eyes,16malesand14females)withrefractoryglaucoma.MeanpreoperativeIOPwas39.3±13.8mmHg.PostoperativemeanIOPwas15.7±7.1mmHg,19.6±12.8mmHgand13.9±14.2mmHgat12,24and56wkrespectively.BCVAwas≥6/60in11eyespreoperatively,andfiveeyeshadBCVA≥6/60at56wkpostoperatively.Preoperatively,morethanfourmedicationswereusedtotreatglaucomain21eyes.At12wkpostoperatively,nomedicationswererequiredtocontrolIOPin20eyes.At56wkpostoperatively,atleastonemedicationwasrequiredtocontrolIOPin10eyes.Overtheentirefollowupperiod,foureyesweretreatedwithyttriumaluminiumgarnet(YAG)laserand14eyesrequiredasecondsurgery.TheAGVwasremovedinfoureyes.CONCLUSION:AGVimplantationreducedIOPandthenumberofmedicationsrequiredtocontrolrefractoryglaucoma.However,therewasahigherriskofdecreasedvision.Long-termfollowupandpromptinterventionarerecommended.

简介：BackgroundAmongpatientsundergoingmitral-valvesurgery,30to50%presentwithatrialfibrillation,whichisassociatedwithreducedsurvivalandincreasedriskofstroke.Surgicalablationofatrialfibrillationhasbeenwidelyadopted,butevidenceregardingitssafetyandeffectivenessislimited.MethodsWerandomlyassigned260patientswithpersistentorlong-standingpersistentatrialfibrillationwhorequiredmitral-valvesurgerytoundergoeithersurgicalablation(ablationgroup)ornoablation(controlgroup)duringthemitral-valveoperation.Patientsintheablationgroupunderwentfurtherrandomizationtopulmonary-veinisolationorabiatrialmazeprocedure.Allpatientsunderwentclosureoftheleftatrialappendage.Theprimaryendpointwasfreedomfromatrialfibrillationatboth6monthsand12months(asassessedbymeansof3-dayHoltermonitoring).ResultsMorepatientsintheablationgroupthaninthecontrolgroupwerefreefromatrialfibrillationatboth6and12months(63.2%vs.29.4%,P<0.001).Therewasnosignificantdifferenceintherateoffreedomfromatrialfibrillationbetweenpatientswhounderwentpulmonary-veinisolationandthosewhounderwentthebiatrialmazeprocedure(61.0%and66.0%,respectively;P=0.60).One-yearmortalitywas6.8%intheablationgroupand8.7%inthecontrolgroup(hazardratiowithablation,0.76;95%confidenceinterval,0.32to1.84;P=0.55).Ablationwasassociatedwithmoreimplantationsofapermanentpacemakerthanwasnoablation(21.5vs.8.1per100patient-years,P=0.01).Therewerenosignificantbetween-groupdifferencesinmajorcardiacorcerebrovascularadverseevents,overallseriousadverseevents,orhospitalreadmissions.ConclusionsTheadditionofatrialfibrillationablationtomitral-valvesurgerysignificantlyincreasedtherateoffreedomfromatrialfibrillationat1yearamongpatientswithpersistentorlong-standingpersistentatrialfibrillation,buttheriskofimplantationofapermanentpacemakerwasalsoincreased

简介：Ifsystolicanteriormotion(SAM)ofaredundantanteriorleafletofthemitralvalveiscombinedwithsystolicthickeningofanasymmetricseptum,(ASH),anarrowoutflowchanneloftheleftventricleisformed.Thisnarrowedoutflowchannelisthenresponsibleforthemidsystolicpressuredifferencebetweenthebodyoftheleftventricleandtheoutflowareaoftheleftventricle.Thisresultsinhypertrophic“obstructive”cardiomyopathy(HOCM).