简介:Asanresearchexampleofthewidelyexistingcooperation-competitionsystems,theauthorspresentanempiricalinvestigationonafruitnutritivefactornetwork.Itisdescribedbyanode-weightedbipartitegraph.Thefruitnutritivefactorsaredefinedasthenodes,andtwonodesareconnectedbyanedgeifatleastonefruitcontainsthesetwonutritivefactors.Thefruitsaredefinedasthecollaborationacts.Thenode-weightW_(nt),whichsignifiesthe'importancedegree'ofeachactornode,isdefinedasthecontentofanutritivefactorinafruit.Theempiricalinvestigationresultsshowsomeuniquefeatures.Thenode-weightdistributionstakeso-called'shiftedpowerlaw'functionforms,buttheact-weightdistributiontakesanormalform.Thedegreeandact-degreedistributionsshowimpulsive-spectrumlikeforms.Theseobservationsmaybehelpfulforthestudyoffruits.Thenetworkdescriptionmethodproposedinthisarticlemaybeuniversalforakindofcooperation-competitionsystems.
简介:Itisstandardpractice,wheneveraresearcherfindsanewgene,tosearchdatabasesforgenesthathaveasimilarsequence.Itisnotstandardpractice,wheneveraresearcherfindsanewgene,tosearchforgenesthathavesimilarexpression(coexpression).Failuretoperformco-expressionsearcheshasleadtoincorrectconclusionsaboutthelikelyfunctionofnewgenes,andhasleadtowastedlaboratoryattemptstoconfirmfunctionsincorrectlypredicted.WepresentheretheexampleofGliaMaturationFactorgamma(GMF-gamma).Despiteitsname,ithasnotbeenshowntoparticipateingliamaturation.ItisageneofunknownfunctionthatissimilarinsequencetoGMF-beta.ThesequencehomologyandchromosomallocationledtoanunsuccessfulsearchforGMF-gammamutationsinglioma.WeexaminedGMF-gammaexpressionin1432humancDNAlibraries.Highestexpressionoccursinphagocytic,antigen-presentingandotherhematopoieticcells.WefoundGMF-gammamRNAinalmosteverytissueexamined,withexpressioninnervoustissuenohigherthaninanyothertissue.OurevidenceindicatesthatGMF-gammaparticipatesinphagocytosisinantigenpresentingcells.Searchesforgeneswithsimilarsequencesshouldbesupplementedwithsearchesforgeneswithsimilarexpressiontoavoidincorrectpredictions.
简介:translationitselfisaculture,Thelanguageisacountryculturecarrier,thetranslationofafilmlikefillingaword
简介:FrequencyresponseoftiltmetersandtidalfactorJUNYANG(杨军)SeismologicalBureauofJiangsuProvince,Nanjing210014.ChinaAbstractTherela...
简介:Objective:Tostudytheexpressionofactivatedepi-dermalgrowthfactorreceptor(EGFR)andtranscrip-tionfactorE2F(E2F)inCondylomaAccuminata(CA)patients.Methods:ImmunofluorescenttechniqueswereusedtoinvestigatetheexpressionofactivatedEGFRandE2FinCApatients.Results:TheexpressionofactivatedEGFRonthemembraneofepithelialcellsinCAlesionswassig-nificantlygreatercomparedtoexpressionleversinthecontrolgroup(P<0.01).Moreover,theco-expres-sionofactivatedEGFRandE2Fwassignificantlyin-creasedcomparedtothecontrolgroup(P<0.01).Conclusion:Ourobservationssuggestthatthein-creaseinactivatedEGFRexpressionmaystimulatehyperplasiainCApatientsthroughtheactivationoftranscriptionfactorE2F.
简介:Objective:Tostudytheexpressionlevelsofplatelet-derivedgrowthfactor(PDGF)andgranulocytecolony-stimulatingfactor(G-CSF)inperipheralbloodandtheirroleinthepathogenesisofCondylomaacuminatum(CA).Methods:Seraweretakenfrom70patientswithCondylomaacuminatumandcomparedwith35healthycontrols.PDGFandG-CSFinserumwerequantitatedusingadualantibodysandwichenzyme-linkedimmunoabsorbentassay(ELISA).Results:SerumconcentrationsofPDGFandG-CSFweresignificantlyincreasedinpatientswithCondylomaacuminatum(CA)comparedtocontrols(P<0.001andP<0.005respectively).SerumlevelsofPDGFandG-CSFcorrelatedwithclinicalseverityofCA,butnosignificantdifferencewasobservedbetweendifferentdurationofdiseasegroups.AsignificantpositivecorrelationwasnoticedbetweenneutrophilcountandG-CSFlevels(γ=0.38,P<0.001),andtheneutrophilcountshowednosignificantcorrelationwithPDGF.Conclusion:TheresultsindicatedthatincreasedexpressionofPDGFandG-CSFinperipheralbloodmightbeinvolvedinpathogenesisofCA.
简介:客观:为了与M-CSFR验证MAF-J6-1受体的抗原协会并且进一步学习M-CSF和它的受体的角色,调停了在支持白血病的房间增长的juxtacrine。方法:MAF-J6-1RRE2的Monoclonal抗体(McAb)和rhM-CSFR的polyclonal抗体(PolyAb)被准备。到M-CSFR的McAbRE2的特性被ELISA被间接ELISA,有J6-1房间殖民地形成的跨neutralizing试金和中立化测试证实。结果:到M-CSFR的净化的RE2的反应活动是超过1:16000。M-CSFR和MAF-J6-1R的禁止的活动能被RE2和anti-M-CSFR抗体堵住。到M-CSFR的RE2的反应能被M-CSFR减少。结论:到M-CSFR的RE2的特性被证实,有M-CSFR的MAF-J6-1R的抗原协会被证明。它建议M-CSF和它的受体调停了auto-juxtacrine刺激能是在白血病或nonhematological恶意的起作用的机制。
简介:代数课本中指出:“在a>0时,|x|>a(?)x<-a或x>a;|x|0”。其实,这一等价性在a≤0时也同样成立。现证明如下:①当a=0吋,i|x|>a即|x|>0的解集显然是:x<0或x>0即x<-a或x>a。
简介:Inthispaperamodeloftransvcrsalfilterispresentedtostudytheadaptivematchofthetimevariantchannel.Theleastmeansquareerrorfil-teringmethodisusedtoobtaintheweightingcoeffcientsofthefilter.Withthepurposeofspeedinguptheconvergenceoftheiterationequationofadaptivefiltering,anadaptivefactoroftheiterationstepsizeμ_aisderivedinthispaper.Theresultofcomputersimulationshowsthatinthecaseofusingadaptiveμ_a,theconvergencespeedoftheiterationequationisincreased2timesapproximatelyincomparisonwithconstantμ_f.Thestudysuggeststhattheadaptivefilterwithadaptiveμ_a.havetheperformancetofollowthechangeoftime-variantcharacteristicsofthechannel.