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简介：Cancerisgenerallyregardedastheresultofabnormalgrowthofcells.AccordingtoWorldHealthOrganization,canceristheleadingcauseofmortalityworldwide.Mothernatureprovidesalargesourceofbioactivecompoundswithexcellenttherapeuticefficacy.Numerousphytochemicalsfromnaturehavebeeninvestigatedforanticancerproperties.Inthisreviewarticle,wediscussseveralnaturalcompounds,whichhaveshownanti-canceractivity.Naturalcompoundsinducecellcyclearrest,activateintrinsicandextrinsicapoptosispathways,generateReactiveOxygenSpecies(ROS),anddown-regulateactivatedsignalingpathways,resultingininhibitionofcellproliferation,progressionandmetastasisofcancer.Severalpreclinicalstudieshavesuggestedthatnaturalcompoundscanalsoincreasethesensitivityofresistantcancerstoavailablechemotherapyagents.Furthermore,combiningFDAapprovedanti-cancerdrugswithnaturalcompoundsresultsinimprovedefficacy.Onthebasisoftheseexcitingoutcomesofnaturalcompoundsagainstseveralcancertypes,severalagentshavealreadyadvancedtoclinicaltrials.Inconclusion,preclinicalresultsandclinicaloutcomesagainstcancersuggestpromisinganticancerefficacyofagentsfromnaturalsources.

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简介：NaturalweakacidicgroundwateroccursintheunconfinedandconfinedaquifersconsistingofQuaternaryandNeogeneunconsolidatedsedimentsnearBeihaiinsouthernGuangxi,China.UndernaturalconditionsthegroundwaterhaslowTDS(lessthan200mgL-1)andlowconcentrationsoftraceelements(lessthan100μgL-1)withadeceasingtendincontentsoftheLanthanides(rareearthelements,lessthan1μgL-1)towardshigheratomicnumber.ThegroundwaterrangesinpHfrom3.33to7.0withanaveragevalueof5.12(evenlowerthanthatoflocalrainwater,5.88).pHvaluesinthegroundwaterareabithigherinrainyseasonsthanthoseindryseasonsanddonotshowsignificantincreasingordecreasingtrendwithtime.TheaveragepHvalueingroundwaterintheconfinedaquifersisevenabitlowerthanthatintheunconfinedaquifer.ComprehensiveanalysesofthegroundwaterenvironmentsuggestthatH+inthegroundwatermaybederivedfromdissociationofH2CO3,releaseoftheabsorbedH3O+inclaylayersandtheacidityofrainwater.TheH2CO3inthegroundwatermaybeformedbydissolutionofCO2(g).Mineralsintheunconsolidatedsedimentarepredominatedbyquartzwithsmallamountofclayminerals.Thesedimentsundergoingalong-termweatheringcontainlowlevelsofsolubleconstitutes.Lackofalkalinesubstancesinthegroundwatersystemisalsohelpfulintheaccumulationofacidityofthegroundwater.

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简介：Theperformanceofawell-designedlayerofsand,andcompositeslikelayerofsandmixedwithshreddedrubbertire(RSM)aslowcostbaseisolators,isstudiedinshaketabletestsinthelaboratory.Thebuildingfoundationismodeledbya200mmby200mmand40mmthickrigidplexi-glassblock.Theblockisplacedinthemiddleofa1mby1mtankfilledwithsand.Theselectedbaseisolatorisplacedbetweentheblockandthesandfoundation.Accelerometersareplacedontopofthefootingandfoundationsandlayer.ThedisplacementofthefootingisalsomeasuredbyLVDT.Thewholesetupismountedonashaketableandsubjectedtosinusoidalmotionswithvaryingamplitudeandfrequency.Sandisfoundtobeeffectiveonlyatveryhighamplitude(>0.65g)ofmotions.Theperformanceofacompositeconsistingofsandand50%shreddedrubbertireplacedunderthefootingisfoundtobemostpromisingasalow-costeffectivebaseisolator.

简介：Inviewofthecurrentgesturerecognitionalgorithmbasedonskincolorsegmentationisnotflexibleandhasweakresistancetotheenvironment,thispaperputsforwardanewmethodofskincolormodelingtoimprovetheadaptabilityofgesturesegmentationwhenitfacetodifferentstates.ThemodelingbuiltbydoublecolorspaceinsteadofonlyoneiscompatiblebothinYCbCrandHSVcolorspacetotrainingtheGaussianmodelwhichcanupdatethethresholdvalueforbinarization.Finally,thispaperdesignedanaturalgesturerecognitionandinteractivesystemsbasedonthedoublecolorspacemodel.Ithasshownthatthesystemhasagoodinteractiveexperienceindifferentenvironments.

简介：西北的华南海深海位于对Qiongdongnan盆(QDN盆)的南部的部分中央，它是为最近的年里的烃探索的一个关键地点。在这研究，作者做了严肃磁性的数据的全面分析，地震调查，核心和剪样，古生物学和geochemical索引的广泛的3D，建议了天然气起源，识别的不同的油和煤气的系统的机制，并且在深海的区域建立了烃累积的模型。我们的盆构造模拟显示QDN盆的进化被多重阶段的构造运动控制例如印度支那欧亚的板碰撞，西藏高举，指责的红河和被Paleogenerifting，晚第三纪消沉，并且始新世的集中的指责和湖的存款描绘的华南海的扩大。钻的结果证明这个区域被过渡的marineterrestrial和neritic-bathyal外形从早渐新世统治。早渐新世的Yacheng形成富于有机物和主要煤气来源的岩石。根据从最近的钻井的geological-geochemical数据，Lingshui，Baodao，Changchang下垂有好产生烃的潜力，在从Paleogene和晚第三纪水库的二出戏被开发的地方。那些水库发生在中央峡谷structural-lithologic陷井地区，Changchang边缘的陷井地区和Baodao的南部的差错梯田下垂。在他们之中，因为各种各样的reservoirforming元素很好被开发，中央峡谷陷井地区为探索有一个大潜力，即，好煤措施来源岩石，从晚第三纪混浊沙岩的足够的水库和海底的扇子，差错连接来源岩石和水库，有效垂直移植，迟了的舞台聚集和有利structurallithological合成套住。这些学习结果在这个区域为烃探索提供一个重要科学基础，由重要商业LS的最近的发现证实了--在Lingshui的中央峡谷的一块煤气的地下垂。

简介：Thispaperextendstheresourcedragstudiesbyempiricallyinvestigatinghowspatialfactorsaffecttheregionaleconomicgrowth.Usingspatialpaneleconometricmodels,thispaperestimatesthedraggingeffectofenergyresourcesoftheYangtzeRiverDeltametropolitanareas.WefindthatthegrowthdragofenergyintheYangtzeRiverDeltaisabout6%onaverage,whichmeansthatenergyconstraintsdecreasetheeconomicgrowthby6%annually,higherthanthenationallevelthathasbeenpreviouslymeasuredintheliterature.Thisresulthastakenintoaccounttheimpactofneighboringcities’economicdevelopment,soastoobtainamoreaccurateestimate.Basedonthesemeasurementresults,weproposesomepolicyrecommendations.

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