简介: 【摘 要】目的:观察单硝酸异山梨酯注射液对心肌梗死后并发症的临床疗效。方法:将 82例患者随机分为治疗组与对照组,每组 41例,治疗组使用单硝酸异山梨酯注射液 20mg混入 5%葡萄糖液 250ml中,静脉滴注,一日一次,连续使用 15天。对照组使用参麦注射液 60ml 混入 5%葡萄糖注射液 250ml中,静脉滴注,一日一次,并口服硝酸异山梨酯片 10mg,一日三次。结果:两组中,治疗组 41例,病死率为 4.8%;对照组 41例,病死率 12.2%。治疗组 41例,心绞痛发生率为 8%,心律失常发生率 5%;对照组 41例,心绞痛发生率为 39%。治疗组治疗效果明显高于对照组。结论:单硝酸异山梨酯注射液,能够有效的防治心肌梗死后并发症,防治冠心病心绞痛、心律失常等。具有起效快、疗效高、安全、不良反应少等特点,是一种安全有效的心血管药物,已成为治疗心血管疾病中的基本药物,在心肌梗塞后并发症中的常规用药。 【关键词】单硝酸异山梨酯注射液;心肌梗死;并发症;疗效 [Abstract] Objective: To observe the clinical effect of Isosorbide Mononitrate Injection on complications after myocardial infarction. Methods: 82 patients were randomly divided into treatment group and control group, 41 cases in each group. The treatment group was given Isosorbide Mononitrate Injection 20mg mixed with 250ml 5% glucose solution, intravenous drip, once a day, for 15 consecutive days. The control group was given Shenmai injection 60ml mixed with 250ml 5% glucose injection, intravenous drip, once a day, and oral isosorbide nitrate tablets 10mg, three times a day. Results: in the two groups, 41 cases in the treatment group, the mortality rate was 4.8%; 41 cases in the control group, the mortality rate was 12.2%. The incidence of angina pectoris and arrhythmia was 8% and 5% in the treatment group and 39% in the control group. The treatment effect of the treatment group was significantly higher than that of the control group. Conclusion: Isosorbide Mononitrate Injection can effectively prevent and treat the complications after myocardial infarction, coronary heart disease, angina pectoris and arrhythmia. It is a safe and effective cardiovascular drug. It has become the basic drug in the treatment of cardiovascular diseases and the conventional medication in the complications after myocardial infarction.
简介:摘要:目的:观察布地奈德混悬液和复方异丙托溴铵溶液雾化吸入治疗哮喘性支气管炎的临床疗效。方法:选择 2017年 2月 -2018年 2月收诊的哮喘性支气管炎患者临床资料 ,共 50例 ,随机分为观察组与对照组 ,各 25例 ,对照组实施吸入用布地奈德混悬液雾化吸入治疗 ,治疗组实施吸入用布地奈德混悬液联合吸入用复方异丙托澳按溶液雾化吸入治疗 ,比较两组患者治疗后的总有效率及其临床症状、体征复常时间的差异。 结果:同对照组哮喘性支气管炎患者用药治疗总有效率比较,观察组哮喘性支气管炎患者结果更好,差异有统计学意义(P< 0.05)。观察组患者咳嗽及咳痰、呼吸困难、肺部哮鸣音及湿罗音消失时间均显著短于对照组,治疗结束后,观察组治疗满意率显著高于对照组,差异有统计学意义 (P< 0. 05)。 结论:吸入用布地奈德混悬液和吸入用复方异丙托澳铵 溶液雾化吸入治疗能够取得良好的治疗效果。