简介:Chronicpancreatitisisanongoingdiseasecharacterizedbypersistentinflammationofpancreatictissues.Withdiseaseprogression,patientswithchronicpancreatitismaydeveloptroublesomecomplicationsinadditiontoexocrineandendocrinepancreaticfunctionalloss.Amongthem,apseudoaneurysm,mainlyinducedbydigestiveenzymeerosionofvesselsinproximitytothepancreas,isarareandlife-threateningcomplicationifbleedingofthepseudoaneurysmoccurs.Atpresent,noprospectiverandomizedtrialshaveinvestigatedthetherapeuticstrategyforthisrarebutcriticalsituation.Theroleofarterialembolization,thetimingofsurgicalinterventionandevensurgicalproceduresarestillcontroversial.Inthisreview,wesuggestthatdynamicabdominalcomputedtomographyandangiographyshouldbeperformedfirsttolocalizethebleedersandtoevaluatetheassociatedcomplicationssuchaspseudocystformation,followedbyarterialembolizationtostopthebleedingandtoachieveearlystabilizationofthepatient’scondition.Withadvancesandimprovementsinendoscopicdevicesandtechniques,therapeuticendoscopyforpancreaticpseudocystsistechnicallyfeasible,safeandeffective.Surgicalinterventionisrecommendedforableedingpseudoaneurysminpatientswithchronicpancreatitiswhoareinanunstablecondition,forthoseinwhomarterialembolizationofthebleedingpseudoaneurysmfails,andwhenendoscopicmanagementofthepseudocystisunsuccessful.Ifableedingpseudoaneurysmislocatedoverthetailofthepancreas,resectionisapreferentialprocedure,whereasifthelesionissituatedovertheheadorbodyofthepancreas,relativelyconservativesurgicalproceduresarerecommended.
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简介:Haemangiopericytoma(HPC)isararevasculartumorwithborderlinemalignancy,considerablehistologicalvariability,andunpredictableclinicalandbiologicalbehavior.HPCcanpresentadiagnosticchallengebecauseofitsindeterminateclinical,radiological,andpathologicalfeatures.HPCgenerallypresentsinadulthoodandisequallyfrequentinbothsexes.HPCcanariseinanysiteinthebodyasaslowlygrowingandpainlessmass.TheprecisecelltypeoriginofHPCisuncertain.OnethirdofHPCsoccurintheheadandneckareas.Exceptionalcasesofhemangioblastomaarisingoutsidetheheadandneckareashavebeenreported,butlittleisknownabouttheirclinicopathologicandimmunohistochemicalfeatures.Thisstudyreportsonacaseofalargesacro-anteriorHPCina65-year-oldmale.
简介:AbstractThe Hoffa fracture is an uncommon fracture. There is a lot of confusion about its diagnosis and management with several conflicting reports in literature. We reported a 25-year-old patient with non-union of Hoffa fracture, and meanwhile tried to develop an algorithm-based treatment for Hoffa fractures. A systematic review of the available literature was performed. Medline, Embase, the Cochrane Library and PubMed were searched for relevant articles. Fifty-five articles were reviewed, and the clinical knowledge base was summarized. The understanding of the mechanism of trauma has become more nuanced. The literature has also evolved to classify the fracture with the purpose of surgical management in mind. This can be used to plan approach and fixation with preservation of blood supply. Classification can also prognosticate the outcomes in Hoffa fracture.
简介:AbstractPerimesencephalic subarachnoid hemorrhage (P-SAH) is a benign subset of subarachnoid hemorrhage. Only two cases of P-SAH during pregnancy have been reported in the literature. We describe a case of P-SAH detected at 29 weeks’ gestation, arose with severe bilateral frontal headache, neck rigidity, and vomiting. A diagnosis of P-SAH was confirmed on magnetic resonance angiography with no evidence of vascular malformation or bleeding sources and conservatively treated. Hemorrhage, vasospasm, and cerebellar edema observed on initial magnetic resonance angiography resolved after two months. The clinical course of P-SAH during pregnancy appears to be favorable. Our case shows for the first time in literature that magnetic resonance angiography is a valid diagnostic test for P-SAH during pregnancy that circumvents radiological risk associated with conventional imaging.
简介:AbstractObjective:Nasal vestibular furunculosis (NVF) is characterized by an acute localized infection of the hair follicle in the skin lining of the nasal vestibule. This study provides an up-to-date narrative analysis on NVF, its presentation, complications and management.Methods:A literature search was conducted electronically with no time constraints using "Nasal Vestibular Furuncolosis" or "NVF" through Medline, Cochrane Library and Web of Science, including MeSH terms with no language restrictions. Included were: Studies that described NVF's presentation and subsequent management and excluded were: Irrelevant studies that did not provide details about NVF's presentation or management, furthermore studies that alluded to Nasal vestibulitis without furunculosis were excluded. There were no limitations on time, up until the review was commenced in May 2020.Results:Seven articles complied with the inclusion criteria. All papers reviewed were from 2015 to 2020. Three out of 4 studies reported duration of symptomatic NVF between 3 and 4 days. The most common presentation of NVF was reported as erythema, swelling, tender over the nasal tip. The most frequent, successful management of NVF frequently included intranasal topical mupirocin and in some cases oral sodium fusidate. NVF was reported to clear within 7 days by 2 studies. There were no randomised studies exploring NVF or NVF management.Conclusion:Although a very common condition, much research is required to allude to the pathophysiology and management of NVF. Future studies should explore the reasons as to the resistance of topical antibiotics in some patients, the differing strains of staphylococcus aureus and their resulting complications, the reasons behind the familiar connection and the most effective management plan for NVF.
简介:WeconsiderthemodificationsofthemonicHermiteandGegenbauerpolynomialsviatheadditionofonepointmassattheorigin.Somepropertiesoftheresultingpolynomialsarestudied;three-termrecurrencerelation,differentialequation,ratioasymptotics,hypergeometricrepresentationaswellas,forlargen,thebehaviouroftheirzeros.
简介:AbstractBackground:Human brucellosis is a neglected public health issue in China and reports of HIV-infected individuals complicated with brucellosis are rare. This report describes the case of an HIV-infected patient complicated with brucellosis. We want to raise awareness of clinical diagnosis of brucellosis among clinicians. Furthermore, we should be more concerned about cases with pyrexia of unknown origin, especially in non-epidemic areas of brucellosis in China.Case presentation:We encountered the case of a 31-year-old HIV-infected male with a CD4+ T lymphocyte count of approximately 300. On May 1, 2019, the patient had onset of non-specific caustic irregular fever with body temperature reaching 41.0 ℃. He was admitted to two medical institutions in Yunnan with pyrexia of unknown origin. Finally, on day 7 of hospitalization in the Public Health Clinical Medical Center in Chengdu City, he was diagnosed as having brucellosis infection based on blood culture results.Conclusions:This is the first reported case of brucellosis concomitant with HIV infection in China. Laboratories in infectious disease hospitals and category A level III hospitals in the southern provinces of China should be equipped with reagents for clinical diagnosis of brucellosis and to strengthen the awareness of brucellosis diagnosis in China. Secondly, in provinces with a high incidence of AIDS and brucellosis such as Xinjiang and Henan, it is recommended to implement a joint examination strategy to ensure the early detection, diagnosis, and treatment of this infection.
简介:Acutepancreatitisduringpregnancyisarareevent,andcanbeassociatedwithhighmaternalmortalityandfetalloss.Gallstonediseaseisthoughttobethemostcommoncausativefactorofacutepancreatitis,but,inmanycases,thecauseremainsunclear.Wereportacaseofa36-year-oldwomanat35wkofgestation,whopresentedwithseverepainconfinedtotheupperabdomenandradiatingtotheback.Thepatientwasdiagnosedwithacuteidiopathicpancreatitis,whichwasmanagedconservatively;sherecoveredwithinseveraldaysandthendeliveredahealthybaby.Thereforeitisimportanttoconsideracutepancreatitiswhenapregnantwomanpresentswithupperabdominalpain,nauseaandvomitinginordertoimprovefetalandmaternaloutcomesforpatientswithacutepancreatitis.
简介:ThepaperconsiderstheKrylov-LanczosandtheEckhoffapproximationsforrecoveringabivariatefunctionusinglimitednumberofitsFouriercoefficients.Theseapproximationsarebasedoncertaincorrectionsassociatedwithjumpsinthepartialderivativesoftheapproximatedfunction.ApproximationoftheexactjumpsisaccomplishedbysolutionofsystemsoflinearequationsalongtheideaofEckhoff.AsymptoticbehaviorsoftheapproximatejumpsandtheEckhoffapproximationarestudied.Exactconstantsoftheasymptoticerrorsarecomputed.Numericalexperimentsvalidatetheoreticalinvestigations.
简介:Thermalconvectiveprecipitation(TCP)oftenoccursovermainlandChinainsummerwhentheareaisdominatedbythewesternPacificsubtropicalhigh(WPSH).ItiswellknownthattheWPSHoftenbringsaboutlargescalesubsidence,thenwhycoulddeepmoistconvectionoccurandwheredoesthewatervaporcomefrom?Inthispaper,adeepconvectiveprecipitationcasethathappenedon2August2003isstudiedinordertoaddressthesetwoquestions.First,thecharacteristicsoftheTCPeventareanalyzedusingtheTropicalRainfallMeasuringMission(TRMM)satellitedata,automaticweatherstationobservations,andthedatafromtheUSNationalCentersforEnvironmentalPrediction(NCEP).Second,watervaporsourcesareidentifiedthroughexaminingsurfaceevaporation,watervaporadvection,andwatervaporfluxdivergencecalculatedbyusingaregionallyaveragedwatervaporbudgetequation.Furthermore,usinganAdvancedRegionalEta-coordinateModel(AREM),contributionsofsensibleandlatentheatfluxestotheTCParecomparedthroughfoursensitivityexperiments.TheresultsshowthatintheregionscontrolledbytheWPSH,surfacetemperaturerisesrapidlyaftersunrise.Uponreceivingenoughsensibleheat,theairgoesupandleadstoconvergenceintheloweratmosphere.Thenthewatervaporassembledfromthesurroundingsandthegroundsurfaceistransportedtotheupperlevels,andafavorableenvironmentfortheTCPforms.Amodeldatadiagnosisindicatesthatabouthalfofprecipitablewatercomesfromtheconvergenceofhorizontalfluxesofwatervapor,andtheotherhalffromsurfaceevaporation,whilelittleisfromadvection.AdditionalsensitivityexperimentsprovethatbothsensibleandlatentheatingareessentialfortheonsetoftheTCP.Thesensibleheatfluxtriggersthermodynamicascendingmotion,andthelatentheatfluxprovideswatervapor,butthecontributiontoTCPfromthelatterisalittlesmallerthanthatfromtheformer.
简介:Objective:Theototoxicityofpovidone-iodinehasbeendocumentedinanimalstudies.However,thereislimitedevidenceoftheseototoxiceffectsinhumans.Thisisthefirstreporttoshowtheototoxiceffectsofpovidoneiodineinahumansubject.Patient:A36-year-oldwomancametoourhospitalcomplainingofleftunilateralpersistenthearingloss.Onemonthbeforepresentation,herchildhadaccidentallystruckheronherleftear.Sheappliedapproximatelythreedropsofpovidone-iodine(10%weight/volume)intoherleftauditorycanal.Immediatelyafterapplication,shefeltseverepainandvertigo.Anaudiogramrevealedsevereleftunilateralsensorineuralhearingloss.Magneticresonanceimagingshowedmildenhancementoftheleftvestibuleandbasalturnoftheleftcochlea.Conclusions:Evenasingleapplicationofpovidone-iodinecouldcausesignificanthearinglossanddisequilibrium.Itshould,therefore,beusedwithcaution.