学科分类
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8 个结果
  • 简介:AIM:Toevaluatetheefficacyandsafetyoftrabeculectomy,phacotrabeculectomyplusintraocularlensimplantation(phacotrab+IOLgroup)andphacoemulsificationwithIOL(phaco+IOL)inprimaryangle-closureglaucoma(PACG).METHODS:Itwasasystematicreviewandmeta-analysis,randomizedcontrolledtrials(RCT)andclinicalcontrolledtrials(CCT)werecollectedthroughelectronicsearchesoftheCochraneLibrary,PubMed,EMbase,WanfangDatabaseonline,ChinesejournalFull-textDatabase,ChineseScientificJournalsFull-textDatabase(fromthedateofbuildingthedatabasetoOctober2010)Wealsocheckedthebibliographiesofretrievedarticles.Alltherelateddatathatmatchedourstandardswereabstracted.ThequalityofincludedtrialswasevaluatedaccordingtotheDutchCochraneCentre.RevMan5.0softwarewasusedforMeta-analysis.RESULTS:Atotalof5RCTand11CCTinvolving1495eyeswereincluded.Theresultsofmeta-analysisshowedthatphacotrab+IOLgroupwassuperiorthantrabeculectomy(trabgroup)(MD-3.93,95%CI[-7.31,-0.54])whichwasalsosuperiorthanphaco+IOLgroup(MD0.52,95%CI[0.10,0.95])indecreasingIntraocularPressure(IOP).Phacotrabgroup(MD-1.45,95%CI[-1.68,-1.22])andphacogroup(MD-1.12,95%CI[-1.87,-0.37])arebothdeeperthantrabgroupintheanteriorchamberdepth.Inincreasingthecoefficientofoutflowfacilityofaqueoushumor(Cvalues)therewasnostatisticaldifferenceinthethreegroups.Andtherewasnostatisticaldifferencebetweenphacotrabgroupsandphacogroupsinvisualacuitybutphacotrabgroupwassuperiorthanphacogroup(MD1.07,95%CI[0.73,1.40])intheuseofIOP-loweringdrugs.Therewasnostatisticaldifferenceamongthreegroups.CONCLUSION:Currentevidencesuggeststhatphacotrab+IOLgroupwassuperiorthantrabgroupwhichwasalsosuperiorthanphaco+IOLgroupindecreasingIOP.Phacotrabgroupandphacogrouparebothdeeperthantrabgroupintheanteriorchamberdepth.PhacotrabgroupwassuperiorthanphacogroupintheuseofIOP-loweringdrugs.

  • 标签: TRABECULECTOMY PHACOEMULSIFICATION PHACOTRABECULECTOMY primary ANGLE-CLOSURE GLAUCOMA
  • 简介:治疗内因性色素膜炎,单纯应用肾上腺皮质激素、免疫抑制剂等可改善症状,但不易控制复发,且常出现药物的副作用。祖国医学认为此病为肝脾蕴热上攻于目、肝肾亏损虚火上炎,治宜滋阴降火,清热解毒。我们对56例病人采用中西医结合疗法,即治疗时用大剂量肾上脾皮质激素突击治疗,待症状缓解后改为中医中药治疗,取得了满意的效果。

  • 标签: 内因性色素膜炎 中西医结合 临床分析 治疗方法
  • 简介:1临床资料2001/2008年共观察糖尿病视网膜病变126例,男70例,女56例,病例来源于内科、眼科住院及门诊患者。1型糖尿病2例,2型糖尿病124例;糖尿病病程10-21(平均13.8)a,伴视网膜病变病程5mo-17a,平均8.5a。糖尿病诊断均符合WHO诊断标准[1]。所有病例近期无严重并发症(酮症酸中毒、严重感染、结核、脑血管意外等),心肺功能基本正常。眼底出血全部经散瞳后裂隙灯、前置镜、双目间接眼底镜检查确诊。

  • 标签: 糖尿病视网膜出血 中西医结合治疗 糖尿病视网膜病变 WHO诊断标准 间接眼底镜检查 糖尿病病程
  • 简介:目的:探讨中西医结合治疗Vogt-小柳-原田综合征(VKH)的临床疗效。方法:对34例68眼VKH采用小剂量糖皮质激素、免疫抑制剂联合中医辨证论治治疗。结果:治愈60眼,好转4眼,总有效率94%。视力≥1.0者24眼,视力≥0.2者64眼。4眼因白内障视力〈0.2。结论:中西医结合治疗VKH可有效的控制炎症,并且可以减少糖皮质激素、免疫抑制剂的用量。

  • 标签: VOGT-小柳-原田综合征 葡萄膜炎 中西医结合治疗
  • 简介:AIM:Tocomparethetrabecularmeshwork(TM)andirisapoptosisoftreatedanduntreatedprimaryopenangleglaucoma(POAG)patients.METHODS:Eighttreatment-naive,newlydiagnosed(group1)and11medlcaiytreated(group2)patientswithPOAGwereincludedinthestudy.Eachpatientunderwentalimbus-basedtrabeculectomy.TheTMandperipheralirisspecimensweredissectedoutandweresnap-frozeninliquidnitrogenandstoredat-80tuntiltheywereassayed.ApoptosisineachgroupwasassesedbyTUNELmethod.RESULTS:Themeanpatientagewas60.6±5.8years(53-68years)vs58.9±8.9years(47-70years)ingroup1andgroup2(P=0.859).Themeantreatmenttimeingroup2was22.2±7.3months(12-34months).ApoptoticindexesinTMandirisweresignificantlyhigherinPOAGpatientsusingmedication(group2)comparedtotreatment-naivePOAGpatients(group1)(P=0.004,0.015;respectively).CONCLUSION:LongtermadministrationoftopicalantiglaucomamedicationscausesadditionaltoxiceffectsonTM.

  • 标签: GLAUCOMA TRABECULAR MESHWORK APOPTOSIS