简介：AIMToobservethetherapeuticeffectofmoxibustiononulcerativecolitisanditsinfluenceonthecolonicmucosalmorphology.METHODSForty-sixpatientswithulcerativecolitiswererandomlydividedintothemoxibustionwithherbalmedicineunderneathgroupandthewesternmedicinegroup.Thirtypatientsweretreatedwiththeabovemoxibustionand16patientswithSalicylayefapyridine(SASP).Thecolonicmucosaof13patientsinthemoxibustiongroupwasobservedbycolonoscopybeforeandafterthetreatment.MucinwasalsoanalyzedbyH.EandAB-PASstaining.RESULTSSeventeenpatientswereclinicallycured,12wereimprovedand1unchangedinthemoxibustiongroup.Inthecontrolgroup,5patientswereclinicallycured,7improvedand4unchanged.ThirteenpatientswithactiveUCweretakenasthesubjectsforhistopathologicanalysisinthisstudy.Thecolonicmucosallesionswereremarkablyimprovedandthecharacteristicofthemucinalsochanged.Inmostsections,thechronicinflammationofmucosawasgeatlyameliorated(P<0.01).Theinflammatorycellinfiltratationmuchdecreasedandneutrophils,disapearedinmostsections(P<0.001).Thegobletcellssignificantlyincreased(P<0.001);cryptparacryptabscessormucosalulcerationwasseen(P<0.001).CONCLUSIONTherateofcureofulcerativecolitisbymoxibustionwithherbalmedicinebeneathissuperiortothatbySASP.Thissortofmoxibustioncaneffectivelyimprovethecolonicmucosallesionsandrestoretheproportionofmucoproteintonearnormal.

简介：瞄准：与胆汁的病理为pyogenic肝脓肿(PLA)调查可行性和laparoscopic外科的治疗学的效果。方法：从2004年1月到2010年10月，有与胆汁的病理会议入口标准相结合的PLA的31个病人在我们的医院里收到了外科的管理。31个病人，13经历了laparoscopic外科(LS组)，18经历了开的外科(OS组)。包括操作时间，intraoperative血损失，手术后的复杂并发症率，一些手术后的医院停留，和脓肿复发率的临床的数据回顾地在二个组之间被分析并且比较。结果：所有病人收到了全身的抗菌素治疗。四个病人在手术前经历了指导超声的经皮的导管排水。手术后的复杂并发症发生在5个病人(16.1%，5/31)在LS组包括2并且3在OS组。一个病人在OS组在普通胆汁管和另一吃的肝脓肿复发保留了演算。没有保留的演算和肝脓肿复发发生在LS组。在二个组，在perioperative时期期间没有死亡。在时间，intraoperative血损失和输送，手术后的复杂并发症率和脓肿复发在二个组之间评估的操作没有重要差别。口头的吸入更早(1.9

简介：AIM:ToevaluatethecompletionrateanddiagnosticyieldofthePillCamSB2-exincomparisontothePillCamSB2.METHODS:Twohundredcasesusingthe8-hPillCamSB2wereretrospectivelycomparedto200casesusingthe12hPillCamSB2-exatatertiaryacademiccenter.Endoscopicallyplacedcapsuleswereexcludedfromthestudy.Demographicinformation,indicationsforcapsuleendoscopy,capsuletype,studylength,completionofexam,clinicallysignificantfindings,timestampofmostdistantfinding...

简介：AIM:Toevaluatethecorrelationofshearwaveelastography(SWE)resultswithliverfibrosishistologyandquantitativefunctionreserve.METHODS:Weeklysubcutaneousinjectionof60%carbontetrachloride(1.5mL/kg)wasgivento12caninesfor24wktoinduceexperimentalliverfibrosis,witholiveoilgivento2controlcanines.At24wk,liverconditionwasevaluatedusingclinicalbiochemistryassays,SWEimaging,lidocainemetabolitemonoethylglycine-xylidide(MEGX)test,andhistologicfibrosisgrading.Clinicalbiochemistryassayswereperformedattheinstitutionalcentrallaboratoryforroutineliverfunctionevaluation.Liverstiffnesswasmeasuredintriplicatefromthreedifferentintercostalspacesandexpressedasmeanliverstiffnessmodulus(LSM).PlasmaconcentrationsoflidocaineanditsmetaboliteMEGXweredeterminedusinghigh-performanceliquidchromatographyrepeatedinduplicate.Liverbiopsysampleswerefixedin10%formaldehyde,andliverfibrosiswasgradedusingthemodifiedhistologicalactivityindexKnodellscore(F0-F4).Correlationsamonghistologicgrading,LSM,andMEGXmeasureswereanalyzedwiththePearsonlinearcorrelationcoefficient.RESULTS:At24wkliverfibrosishistologicgradingwasasfollows:F0,n=2(control);F1,n=0;F2,n=3;F3,n=7;andF4,n=2.SWELSMwaspositivelycorrelatedwithhistologicgrading(r=0.835,P<0.001).Specifically,theF4grouphadasignificantlyhigherelasticmodulusthantheF3,F2,andF0groups(P=0.002,P=0.003,andP=0.006,respectively),andtheF3groupalsohadasignificantlyhighermodulusthanthecontrolF0group(P=0.039).LSMwasnegativelyassociatedwithplasmaMEGXconcentrationsat30min(r=-0.642;P=0.013)and60min(r=-0.651;P=0.012),timeto?ofthemaximumconcentration(r=-0.538;P=0.047),andtheareaunderthecurve(r=-0.636;P=0.014).Multiplecomparisonsshowedidenticaldifferencesinthesethreemeasures:significantlylowerwithF4(P=0.037)andF3(P=0.032)ascomparedtoF0a