简介:摘要:目的:根据近年来产妇臀位外倒转术的实施情况,结合实践案例分析小剂量舒芬太尼腰麻联合利多卡因连硬膜外麻醉的临床应用情况,判断其对臀位外倒转术成功概率构成的影响。方法:以某医院在2019年到2021年期间收治的80名妇产科病人为例,将他们随机分成两组,每组各40人,其中A组选用2%的利多卡因,B组选用2%的利多卡因和小剂量舒芬太尼。主要研究两组孕妇感觉阻滞的起效时间和达到T8平面的时间、手术期间的麻醉效果等。结果:对比A B两组的实验结果发现,B组感受到的阻滞起效时间和达到T8平面的时间都有所下降,手术期间的麻醉效果得到了明显改善,进一步提高了孕妇在手术期间的舒适度。结论:2%的利多卡因和小剂量舒芬太尼硬膜外,麻醉能进一步改善孕妇臀位外倒转术的成功概率,降低手术期间的疼痛感,且不会对新生儿构成不良影响,因此可以在基层医院中广泛应用。
简介:摘要:目的 分析2022年四川省其他感染性腹泻的流行病学特征,为疾病防控提供科学依据。方法 收集中国疾病预防控制信息系统传染病监测系统中2022年四川省报告的其他感染性腹泻病例相关资料,采用描述性流行病学方法进行分析。结果 2022年全省报告病例56964例,死亡2例,报告发病率68.04/10万,男性高于女性,男女性别为1.12:1;全年均有病例报告,季节分布规律与既往不同,呈单峰分布,发病高峰为2-3月,发病率居全省前5位的依次为宜宾市、绵阳市、广元市、自贡市、阿坝州。人群以0-3岁婴幼儿为主。讨论 2022年四川省其他感染性腹泻报告发病率呈持续上升趋势,疫情形势值得关注。
简介: [摘要 ] 目的 探讨美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎的疗效及其对炎性因子的影响。 方法 选取 2018年 1月~ 2020年 1月我院收治的溃疡性结肠炎患者 80例,随机分为两组,每组各 40例,两组患者均予常规对症治疗,同时两组均予美沙拉嗪缓释颗粒,观察组同时加用双歧三联活菌胶囊,治疗后比较两组患者治疗后的临床疗效,以及两组患者治疗前后 TNF-α、 IL-10水平的变化情况及两组患者治疗前后的临床症状积分变化情况。结果 观察组治疗后的总有效率为 95.00%,显著高于对照组的总有效率 70.00%,两组疗效比较差异具有显著性( P<0.05)。治疗后,两组患者的炎性因子 TNF-α、 IL-10水平较治疗前显著降低( P<0.05)。且观察组患者治疗后的 TNF-α、 IL-10水平显著低于对照组( P<0.05)。观察组患者治疗后的临床症状积分为( 2.56±0.85)分,与治疗前及对照组比较,差异有统计学意义( P<0.05)。 结论 美沙拉嗪联合双歧三联活菌治疗溃疡性结肠炎疗效确切,且可以抑制炎症反应,值得临床推广和应用。 [关键词 ] 溃疡性结肠炎 ;美沙拉嗪 ;双歧三联活菌 ;炎性因子 [Abstract] Objective To investigate the efficacy of mesalazine combined with Bifid Triple Viable Bacteria in the treatment of ulcerative colitis and its influence on inflammatory factors. method Methods: 80 patients with ulcerative colitis in our hospital from January 2018 to January 2020 were selected and randomly divided into two groups, 40 cases in each group. Both groups were given conventional symptomatic treatment, while the two groups were given mesalazine sustained-release granules. The observation group was also given Bifid Triple Viable capsules. After treatment, the clinical efficacy of the two groups of patients after treatment, as well as TNF - α, IL-10 water before and after treatment, were compared between the two groups The changes of the two groups of patients before and after treatment of clinical symptoms integral changes. Results the total effective rate of the observation group was 95.00%, which was significantly higher than that of the control group (70.00%). There was a significant difference between the two groups (P < 0.05). After treatment, the levels of inflammatory factors TNF - α and IL-10 in the two groups were significantly lower than those before treatment (P < 0.05). The levels of TNF - α and IL-10 in the observation group were significantly lower than those in the control group (P < 0.05). The clinical symptom score of the observation group after treatment was (2.56 ± 0.85), and the difference was statistically significant (P < 0.05). Conclusion mesalazine combined with Bifid Triple Viable Bacteria is effective in the treatment of ulcerative colitis, and can inhibit inflammatory reaction, which is worthy of clinical promotion and application.
简介:摘要:目的:探究成人隐匿性自身免疫性糖尿病(LADA)漏诊为2型糖尿病(T2DM)的原因分析及干预对策。方法:本研究以2022年4月-2023年4月间住院的LADA患者72例为主要对象,按照可否对T2DM漏诊分为42例漏诊组、30例未漏诊组。通过单因素和多因素Logistic统计,统计所有患者的临床资料,分析患者的年龄、体重(BMI)指数、肌酐、病程、糖尿病自身抗体、总胆固醇、用药及尿酮体等指标,探讨其发生的因素及护理措施。结果:经单因素及多因素Logistic回归分析,表明,LADA漏诊为T2DM主要与年龄、病程、BMI、胰岛细胞抗体(ICA)、胰岛素自身抗体(IAA)及谷氨酸脱羧酶抗体(GAD-Ab)等因素相关(P<0.05)。结论:LADA被漏诊为T2DM的病因众多,各因素之间相互作用,对其给予针对性地预防和诊断,减少漏诊,改善疾病。