简介：Objective:Toanalyzetheclinicopathologiccharacteristicsandprognosticfactorsofsmallgastrointestinalstromaltumor(GIST)ofthestomach.Methods:Atotalof31smallgastricGISTpatients,including10malesand21females,withamedianageof58years(37-81years),whounderwentsurgeryatanytimefrom1999to2012wereincludedinthisstudy.Theclinicalrecordsofthepatientswereanalyzedretrospectively.Results:Abdominaldiscomfortandpain(10cases,32.3%,respectively)werethetwomostcommoncomplaintsamongthepatients.Allpatientsreceivedsurgery,11receivedgastricwedgeresection,11receivedsubtotalgastrectomy,5receivedlaparoscopicgastricwedgeresection,and4receivedendoscopicsubmucosaldissection.Nosevereadversecomplicationwasobserved.Atotalof29patients(93.5%)werefollowedup.Duringthefollow-up,2patientswerefoundtoexhibittumorrecurrence,and1patienthadlivermetastases.Onepatientdiedoftumorprogression,whileanotherdiedofanothermalignanttumor.Medianprogressionfreesurvival(PFS)timewas120.3months,andmedianoverallsurvival(OS)timewas130.4months.Conclusion:SmallgastricGISThasbetterprognosis.Surgeryisthebestchoicefortherapy.Micro-invasiveproceduresaresafeandeffectiveforelectivepatients.Tumornecrosis,tumorbleeding,andmuscleinvasionarepotentialprognosticfactorsofsmallgastricGIST.

简介：Objective:Toinvestigatetherecurrencesites,riskfactors,andprognosisofpatientswithpersistentorrecurrentsquamouscellcarcinoma(SCC)ofthecervixwithinoneyearafterundergoingconcurrentchemoradiotherapy(CCRT).Methods:Clinicaldataof30patientswithpersistentorrecurrentSCCofthecervixwithinoneyearafterCCRTbetweenJuly2006andJuly2011wereanalyzedretrospectively.Thesedatawerecomparedwiththoseof35SCCcaseswithnosignsofrecurrenceaftercompleteremission.These35patientsweretreatedduringthesameperiod(between2006and2011)andselectedrandomly.Results:Amongthese30patients,25exhibiteddistantmetastasesofwhich14wereobservedwithin6monthsafterCCRT.Univariateanalysisshowedhigherincidenceofpelvicorpara-aorticlymphadenectasisandSCC-ag>10ng/mLinthegroupwithpersistentorrecurrentdiseasebeforetreatment(P<0.01).Multivariateanalysisbylogisticregressionrevealedthatthepre-therapeuticpelvicorpara-aorticlymphnodeenlargementandSCC-ag>10ng/mLweretheindependentriskfactors.Palliativechemotherapywasthemaintreatmentoptionforpatientswithpersistentorrecurrentdisease.The2-yearsurvivalratewas21.7%,andthemediansurvivaltimewas17months.Conclusion:PatientswithpersistentorrecurrentSCCofthecervixafterCCRTexhibitedahighrateofdistantmetastasiswithpoorprognosis.Thepre-therapeuticpelvicorpara-aorticlymphnodeenlargementandSCC-ag>10ng/mLwereidentifiedastheindependentriskfactorsforpersistentorrecurrentSCCwithin1yearafterCCRT.