简介：BACKGROUND:Previousstudiesreportedthatfrontal-temporal-parietal-occipitalpathologicalchangesanddiseasedrangeintherightcerbralhemispherewerecorrelatedwithneglect.Butstudiesonthecorrelationofneglectwithdiseasedregionandareainpatientswhosufferfrominitialattackofsinglefocusofcerebralinfarction(CI)inleftandrightcerebralhemispheresarefew.OBJECTIVE:ToobservethestatusofneglectinpatientswhosufferfromsinglefocusofCIincerebralhemisphereandanalyzethecorrelationofneglectwithdiseasedregionandareaofCI.DESIGN:CaseanalysisSETTING:TreatmentCenterforCardiocerebrovascularDisease,SecondHospitalofXiamencity;DepartmentofNeurology,FirstHospitalAffiliatedtoBaotouMedicalCollege.PARTICIPANTS:AlltheCIpatientshospitalizedintheDepartmentofNeurology.FirstHospitalAffiliatedtoBaotouMedicalCollegefromJune1998toMay2001wereretrieved.Inclusivecriteria:①PatientswhosufferedfrominitialattackofCI.whichwasconfirmedbyskullCTorMRIwithin24hoursafteronsetandpresentedsinglefocusincerebralhemisphere.②beconsciousandcouldcooperateintheexamination.③didnotreceiveformaleducation,butcoulddoaccountsandsomesimplewritingandreading.④Patientswithhomonymoushemianopiawereexcludedthroughtheexaminationofperimeter.⑤Informedconsentswereobtainedfromallthepatients.Among67patientswhomettheinclusivecriteria.33sufferedfromCIintheleftcerebralhemisphereand34intherightcerebralhemisphere.METHODS:①PatientsreceivedneglectsupplementexaminationandChineseaphasiaexaminationwithin2.5to3monthsaftertheattackofCI.Thediagnosticcriteriaofneglectinthetestsoflinecancellation.1inebisectionandcopyingthefigureswereasfollows:InthelinecancellationtestbasedonthemethodofAlbert.patientswhocouldnotcanceloneormorelineswereregardedasabnormal.InthelinebisectiontestbasedonthemethodofPeter.patientswholeftdeviated1.16%

简介：Drugscancauseobviousdamagetothebrain.Toverifytherelationshipbetweenacupuncture,neurotrophicfactorexpressionandbraincellstructuralchanges,thisstudyestablishedaratmodelofheroinrelapseusingintramuscularinjectionofincreasingamountsofheroin.Duringthedetoxificationperiod,ratmodelsreceivedacupunctureatBaihui(DU20)andDazhui(DU14).Electronmicroscopydemonstratedthatthestructureoftheventraltegmentalareainheroinrelapseratsgraduallybecamenormalizedafteracupuncturetreatment.Immunohistochemicalstainingexhibitedthattheexpressionofbrain-derivedneurotrophicfactorandglialcellline-derivedneurotrophicfactorincreasedintheventraltegmentalareafollowingacupuncture.Moreover,theeffectsweresimilartothatofmethadone,atypeofmedicinecalledanopioid.ResultssuggestedthatacupunctureatBaihuiandDazhuiprotectedbrainneuronsagainstinjuryinratswithheroinrelapsebypromotingbrain-derivedneurotrophicfactorandglialcellline-derivedneurotrophicfactorexpression.