简介:Anewapparatuswasdesignedtomeasuretheelectromagneticforceandacomputationalstudyofthetravelingmagneticfield(TMF)anditsapplicationtotheGa-In-Snmelt(withlowmeltingpoint),thentheforcesonAl,Mg,andLimelt,weresimulated.TheresultshowthattheelectromagneticforceonthemeltincreaseslinearlywiththeincreasinglengthofthemeltintheTMF.TheTMF-inducedLorentzforceincreaseswithincreasingfrequency,andthendecreases.Themaximumvalueisobtainedwhenthecurrentfrequencyis160Hz,overthatfrequencytheforcedecreasesrapidly.Whentheiron-coreisactivated,theforceincreaseswhenthemeltclosestotheiron-core.TheLorentzforceshaveinversely-proportionalrelationshipswiththeelectricalresistivity,thedfx/dρdecreasesandthedfy/dρincreaseswiththeincreasingelectricalresistivity(df/dρistheslopeoftheLorentzforceprofile).
简介:OurexperimentsshowthatexternalfocusingandinitiallaserenergystronglyinfluencesfilamentgeneratedbythefemtosecondTi–sapphirelaserinair.Theexperimentalmeasurementsshowthefilamentlengthcanbeextendedbothbyincreasingthelaserenergyandfocallengthoffocusinglens.Ontheotherhand,theplasmafluorescenceemissioncanbeenhancedbyincreasingthelaserenergywithfixedfocallengthordecreasingthefocallength.Inaddition,thecollapsedistancemeasuredexperimentallyarelargerthanthecalculatedonesowingtothegroup-velocity-dispersioneffect.Inaddition,wefindthatthelinewidthsofthespectrallinesfromN2isindependentoffilamentpositions,laserenergiesandexternalfocusing.
简介:QBO-likeOscillationsInducedbyLocalThermalForcingZhangDaizhou;(张代洲),andQinin(秦瑜)(DepartmentofGeophysics,PekingUniversity,Beiji...
简介:WiththerapiddevelopmentofforeigntradeinChina,industrialimportandexporthasbeenanabsolutesubjectinrecentyears.Thehugetradesurplusofimportandexporttradeofindustrialproductsbringsnotonlyhighprofits,butalsopollutioncostsaswell.Basedontheconceptofwaterpollutionfootprints(WPFs),thisstudyappliestheinput-outputmethodandcalculatespollutant-producingcoefficientsof20majorindustrialsectorsinChinaandinvestigatestheWPFscausedbytheimportandexporttradesoftheseindustrialsectors.TheresearchresultsshowthatWPFresultingfromexportsexceedsthatofimportsfrom2011to2015inChina.Thenetinflowofpollutionfootprintismainlyfrompapermills,printingandstationerymanufacturing,andtextileindustry;whereasagreatnumberofWPFsaretransferredtoothercountriesbythesesectors,suchasmetalmininganddressingindustryandoilandnaturalgasexploitationindustry.
简介:与他们在文化经历无限的自强并且在身体区分进所有房间类型的能力,人的胚胎的干细胞(hESCs)为治疗保持大潜力当前不治之症。为针的绳索损害和有斑点的退化的二基于hESC的房间治疗被推进了进人的临床的试用。尽管有这快速的进步,基于hESC的房间治疗的一关键挑战是由接受者的导出hESC的房间的allogeneic免疫者拒绝。这个问题能被病人特定的体的房间的原子reprogramming被最近的突破与定义因素在导致的pluripotent干细胞(iPSCs)的技术减轻它能为房间治疗成为自体同源的房间的可更新的来源。然而,揭示反常epigenetics,genomic稳定性和iPSCs的immunogenicity的最近的研究在基于iPSC的治疗上提起了安全担心。与iPSC衍生物的immunogenicity有关的最近的调查结果将在这评论被总结。
简介:在vivo,研究证明那个树枝状的房间(DC)机能障碍发生在肿瘤微型环境。当肿瘤由许多种房间组成,不成熟的DC(imDCs)上的肿瘤房间的直接效果在vitro为进一步的研究被需要。在现在的学习,骨头导出髓的imDCs在vitro与淋巴瘤,hepatoma和menaloma房间被孵化,在imDCs的表面分子被流动cytometry决定。然后,imDCs与肿瘤孵化了房间或控制imDCs进一步与肿瘤lysates被搏动然后与splenocytes孵化了执行混合淋巴细胞反应。DC依赖的肿瘤抗原特定的T房间增长,和IL-12分泌物被流动cytometry,和连接酶的immunosorbent试金分别地决定。最后,DC依赖的联系肿瘤的抗原特定的CTL被连接酶的immunospot试金决定。结果显示出那肿瘤cell-DC孵化下面调整在imDCs的表面分子例如CD80,CD54,CD11b,CD11a和MHC班II分子。DC依赖的抗原特定的T房间增长和IL-12分泌物的能力被肿瘤房间孵化也在vitro减少。最重要地,为DC的antigenic特定的CTLpriming的能力被孵化也与肿瘤房间减少。在礼品,在vitro,学习证明肿瘤房间合作孵化和合作孵化系统导致的DC的有缺点的能力可能直接为肿瘤免疫者房间的未来学习是有用的相互作用并且为药屏幕有免疫力调整。
简介:AIM:Toestimatethepotentialsystemiceventsduringandafterretinopathyofprematurity(ROP)screening.METHODS:Aprospectiveanddescriptivedesignedstudywasconductedtodetectthephysiologicandpathologicalchanges24hbefore,during,and72hafterROPscreening.Controlbloodpressure(BP),saturation,pulserate,andbodytemperaturewereroutinelytakenatvarioustimeinternalsbeforeandafterscreening.Adverseeffectspertaintocardiovascularsystem,respiratorysystem,gastricsystem,urinarysystemandnervoussystemwereretrospect0-72hafterROPscreeningata24-hourinterval.RESULTS:Totally1254prematuritybabiesreceivingROPscreeningduringJan.1st2013toDec.31th2013wereenrolledinoursurvey.Comparedtocontrolvitalsigndatatakenbeforetheexamination,therewasafluctuationinthediastolicBPwiththeincreased3.03mmHg(P=0.04)after3dosesofmydriaticdrops.Immediatelyaftertheexamination,therewasafurther12.64mmHg(P<0.01)increaseinsystolicBPanda7.24mmHg(P<0.01)indiastolicBP.Themeanpulserateduringexaminationwas22.4bpm(P<0.01)higherthanthe133.3±9.0bpmcontrollevel.Theoxygensaturationsharedanaveragedropof5%(P<0.01)duringscreening.Inprematuritywithpostconceptionalagelessthan31wk,theincidenceofapnea(23.5%),necrotizingenterocolitis(NEC)(8.7%),gastricresidual(25.4%)andupperdigestivetracthemorrhage(6.4%)alsodemonstratedasignificantrise(P<0.01).CONCLUSION:Inourstudysample,ROPscreeningwasassociatedwithNEC,gastricresidualandupperdigestivetracthemorrhage.Thesegastrointestinalsideeffects,alongwithbreathactivitypatternchangeandvitalsignsindicatorsfluctuation,mayberesultsofadditionalstressresponses.
简介:Ithasbeenknownforsometimethatstraininjuriesoccurthroughtheexcessivelengtheningofamuscle.~(1–3)However,theprecisemechanismforstraininjuryremainselusiveandhasbeenthesubjectofrecentdebateintheJournalofSportandHealthScience,~(4–9)butitseemssensibletoconsidermechanismsatthelevelofthemusclefiber.Itwaspreviouslybelievedthatdamagewastheresultofnon-uniformstretchingofsarcomeres
简介:ThePMD-inducedpulsebroadeningmaycausethedegradationofreceiversensitivityandhasnegativeeffectsonthepowerspectrumofreceivedsignals.TheexpressionsofPMD-inducedpulsebroadeningeffectsonreceiversensitivityarederivedbasedontheconceptofmeansquarepulsewidth.TheeffectsofPMDonthespectrumofreceivedpowerareanalyzedindetail.Finally,theschemeisdiscussedwithwhichthepowerofacertainfrequencycomponentisextractedasafeedbackcontrolsignalinaPMDcompensationsystem.
简介:ObjectiveTodetectearlysignsofnoise-inducedhearingloss(NIHL)inmilitarypilotswithouthearingcomplaints.MethodsPuretoneaudiometryandacousticreflexthresholdsweretestedin36militarypilots(72ears)withnoiseexposurehistorybutnocomplaintsofhearingloss.Conventionaltestfrequencies(0.25-8kHz)andextendedhighfrequencies(EHF,10and12.5kHz)wereincludedinaudiometry.Whitenoiseandpuretonesat0.5,1,2,and4kHzwereusedforacousticreflextests.Twentynormalhearingsubjects(40ears)withnoexposuretooccupationalnoisewereusedascontrols.ResultsPuretonethresholdsatallconventionalfrequenciesandatEHFswereelevatedinthepilots,withthemaximumshiftat4kHz,comparedwithcontrols(p<0.01).ThepilotsalsoshowedelevatedARTtowhitenoiseanddecreaseddifferentialsbetweenwhitenoiseandpuretoneARTs(p<0.01).ConclusionEarlysignsofNIHLarepresentinsomesymptom-freemilitarypilots.Highfrequencyhearingthresholdshift,elevatedwhitenoiseARTanddecreaseddifferentialbetweenwhitenoiseandpuretoneARTsmaybeobjectiveindicatorsofearlyNIHL.
简介:Inthispaper,opticalcross-connection(OXC)inducedcrosstalkhasbeencarefullyanalyzedformultiwavelengthall-opticalnetworks.Formulaearederivedforcalculatingthecrosstalkpowerofhomowavelengthcrosstalkandthetotalcrosstalkatthereceiverend.TheresultsshowthattheopticalswitchesinducedcrosstalkdominatesoverothercrosstalkcomponentsofOXC,andtheaccumulatedhomowavelengthcrosstalkincreasesalmostlinearlywiththeincreasingoftheOXCnumber.Atthereceiverend,theheterowavelengthcrosstalkinducedbythereceiveropticalfilterhasthesameorderasthatofhomowavelengthcrosstalkofOXC.Theresultsofdifferentopticalcomponentsmodelarealsodiscussed.
简介:Ahybridcontrolplatformisinvestigatedinthispapertomitigatemicrovibrationstoagroupofvibrationsensitiveequipmentinstalledinamicroelectronicsfacilitysubjecttonearbyroadvehicle-inducedhorizontalandverticalgroundmotions.Thehybridcontrolplatform,onwhichmicroelectronicsequipmentisinstalled,ismountedonabuildingfloorthroughaseriesofpassivemountsandcontrolledbyhydraulicactuatorsinbothhorizontalandverticaldirections.Thecontrolplatformisanelasticbodywithsignificantbendingmodesofvibration,andasub-optimalcontrolalgorithmisusedtomanipulatethehydraulicactuatorswithactuatordynamicsincluded.Thefiniteelementmodelandtheequationsofmotionofthecoupledplatform-buildingsystemarethenestablishedintheabsolutecoordinatetofacilitatethefeedbackcontrolandperformanceevaluationoftheplatform.Thehorizontalandverticalgroundvibrationsatthebaseofthebuildinginducedbynearbymovingroadvehiclesareassumedtobestationaryrandomprocesses.Atypicalthree-storymicroelectronicsbuildingisselectedasacasestudy.Thecasestudyshowsthattheverticalvibrationofthemicroelectronicsbuildingishigherthanthehorizontal.TheuseofahybridcontrolplatformcaneffectivelyreducebothhorizontalandverticalmicrovibrationsofthemicroelectronicsequipmenttothelevelwhichsatisfiesthestringentmicroscalevelocityrequirementspecifiedintheBoltBeranek&Newman(BBN)criteria.
简介:AbstractNeurosurgical procedures cause inevitable brain damage from the multitude of surgical manipulations utilized. Incisions, retraction, thermal damage from electrocautery, and intraoperative hemorrhage cause immediate and long-term brain injuries that are directly linked to neurosurgical operations, and these types of injuries, collectively, have been termed surgical brain injury (SBI). For the past decade, a model developed to study the underlying brain pathologies resulting from SBI has provided insight on cellular mechanisms and potential therapeutic targets. This model, as seen in a rat, mouse, and rabbit, mimics a neurosurgical operation and causes commonly encountered post-operative complications such as brain edema, neuroinflammation, and hemorrhage. In this review, we elaborate on SBI and its clinical impact, the SBI animal models and their clinical relevance, the importance of applying therapeutics before neurosurgical procedures (i.e., preconditioning), and the new direction of applying venom-derived proteins to attenuate SBI.
简介:Thisletterpresentsanewanalyticalapproximationforwave(current)-induceddynamicsoilresponseinmarinesediments.Inthemodel,thethird-orderapproximationforwave-currentinteractionsisemployedfortheflowmodel,whileBiot’sdynamicporo-elasticmodelisusedtosimulatetheporousflowinaseabed.Thenewlyanalyticalsolutionisvalidatedwiththefieldobservations.Basedonthesolution,effectsofcurrentsandwave-nonlinearityonsoilresponseareexaminedandaparametricstudywillbecarriedouttoexaminetheinfluenceofcurrentsontheliquefactionpotential.
简介:Stochasticresonance(SR)phenomenonofthesystemthatissubjecttotheasymmetrictwo-statenoiseisinvestigatedfromthebroadsense.Itisshownthattheamplitudesoftheoutputsignalexhibitthenon-monotonicdependenceontheinputsignalfrequencyω,andtheparametersdescribingtheasymmetrictwo-statenoise,suchasthetransitionrateλ,theorderparameterkdescribingtheasymmetricdegreeofthetwo-statenoise,andthenoisestrengthD.
简介:Near-fleldcoupledplasmonicsystemsgenerallyachieveplasmonicallyinducedtransparency(PIT)usingonlyone-waybright-darkmodecoupling.However,itischallengingtorealizesuchwell-designeddevices,mainlybecausetheydependsignificantlyonthepolarizationdirection.Weexploitsurfaceplasmonssup-portedbytwocrossedlayersofgraphenenanoribbons(GNRs)toachievedynamicallytunablePIT,whereeachGNRoperatesasboththebrightanddarkmodessimultaneously.TheproposedPITcanresultfromeitherone-waybright-darkmodeinteractionsorbidirectionalbright-brightandbright-darkmodehybrid-izedcouplingwhenthepolarizationisperpendicular/paralleloratanangletotheGNRs,respectively.Additionally,identicalribbonwidthsyieldpolarization-insensitivesingle-windowPIT,whereasdifferentribbonwidthsproducepolarization-dependentdouble-windowPIT.Weexaminetheproposedtechniqueusingplasmonwavefunctionsandthetransfermatrixmethod;analyticalandnumericalresultsshowex-cellentagreement.ThisstudycanprovidephysicalinsightintothePITcouplingmechanismsandadvancetheanulicabilitvandversatilityofPIT-basedsensingplatformsandotheractivedevices.
简介:Wereportsingle-shotdamagethresholdasafunctionofpulseduration(50-900fs)forMgF2/ZnS800-nmomnidirectional-reflectionfilm,interferencefilter,andgoldfilm.Theresultsindicatethatthedamagewithultrashortpulseisnonthermal,whichisdifferentfromthatwithlongpulse.Additionally,theablationcraterdepthsof45°high-reflectionfilmandinterferencefilterarepresented.Alogarithmicrelationbetweentheablationdepthandpulsefluence,whichissimilartothatoftransparentmaterials,isfound.