Quantitative volumetric analysis of the optic radiation in the normal human brain using diffusion tensor magnetic resonance imaging-based tractography

(整期优先)网络出版时间:2014-03-13
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Toattainthevolumetricinformationoftheopticradiationinnormalhumanbrains,weperformeddiffusiontensorimagingexaminationin13healthyvolunteers.Simultaneously,weusedabrainnormalizationmethodtoreduceinpidualbrainvariationandincreasetheaccuracyofvolumetricinformationanalysis.Inaddition,tractography-basedgroupmappingmethodwasalsousedtoinvestigatetheprobabilityanddistributionoftheopticradiationpathways.Ourresultsshowedthatthemeasuredopticradiationfibertractvolumewasarangeofabout0.16%andthatthefractionalanisotropyvaluewasabout0.53.Moreover,theopticradiationprobabilityfiberpathwaythatwasdeterminedwithdiffusiontensortractography-basedgroupmappingwasabletodetectthelocationrelativelyaccurately.Webelievethatourmethodsandresultsarehelpfulinthestudyofopticradiationfibertractinformation.