Thestudyofneuronalplasticityunderpathologicalconditionsisnowamajorpointoffocusonthefieldofneurologicalrecovery.Aftertherepeatedfailureofacuteneuroprotectionstrategiesforstroketreatment,thedesignofstudiesaimedatpromotingthereconstructionofneuronalnetworkshasbecomeessential.Methodsforthedeliveryoftherapeuticagentsonasteadydosage,thuspreventingpharmacologicalpeaksorexcessivemanipulationofexperimentalanimals,arethusrequired.Additionally,methodsthatallowthevisualizationofneurologicalremodelingprocessesarefundamentaltotheunderstandingofhowatherapeuticagentexertsitsfunction.Herewedescribehowtheuseofminiosmoticpumpsforthesteadydeliveryofsuchagents,togetherwithtracttracerinjections,canbecombinedtounveilimportantinformationonhowthebrainchangesafterstrokeandhowtherapeuticagentspromotebrainremodelingrecovery.
