简介:
简介:Navigationsystembasedontheanimalbehaviorhasreceivedagrowingattentioninthepastfewyears.Thenavigationsystemsusingartificialpheromonearestillfewsofar.Forthisreason,thispaperpresentsourresearchthataimtoimplementautonomousnavigationwithartificialpheromonesystem.Byintroducingartificialpheromonesystemcomposedofdatacarriersandautonomousrobots,theroboticsystemcreatesapotentialfieldtonavigatetheirgroup.Wehavedevelopedapheromonedensitymodeltorealizethefunctionofpheromoneswiththehelpofdatacarriers.Weintendtoshowtheeffectivenessoftheproposedsystembyperformingsimulationsandrealizationusingmodifiedmobilerobot.Thepheromonepotentialfieldsystemcanbeusedfornavigationofautonomousrobots.
简介:Thispaperproposedanovelhumanoidroboteye,whichisdrivenbysixPneumaticArtificialMuscles(PAMs)androtateswith3DegreeofFreedom(DOF).Thedesignofthemechanismandmotiontypeoftheroboteyeareinspiredbythatofhumaneyes.Themodelofhumanoidroboteyeisestablishedasaparallelmechanism,andtheinverse-kinematicproblemofthisflexibletendonsdrivingparallelsystemissolvedbytheanalyticalgeometrymethod.Asanextension,thesimulationresultforsaccadicmovementispresentedunderthreeconditions.Thedesignandkinematicanalysisoftheprototypecouldbeasignificantsteptowardsthegoalofbuildinganautonomoushumanoidroboteyewiththemovementandespeciallythevisualfunctionssimilartothatofhuman.
简介:Thispaperaddressesthedesignofabiomimeticfishrobotactuatedbypiezoceramicactuatorsandtheeffectofartificialcaudalfinsonthefishrobot'sperformance.Thelimitedbendingdisplacementproducedbyalightweightpiezocompositeactuatorwasamplifiedandtransformedintoalargetailbeatmotionbymeansofalinkagesystem.Caudalfinsthatmimictheshapeofamackerelfinwerefabricatedforthepurposeofexaminingtheeffectofcaudalfincharacteristicsonthrustpro-ductionatanoperatingfrequencyrange.Thethicknessdistributionofarealmackerel'sfinwasmeasuredandusedtodesignartificialcaudalfins.ThethrustperformanceofthebiomimeticfishrobotpropelledbyfinsofvariousthicknesseswasexaminedintermsoftheStrouhalnumber,theFroudenumber,theReynoldsnumber,andthepowerconsumption.Forthesamefinareaandaspectratio,anartificialcaudalfinwithadistributedthicknessshowsthebestforwardspeedandtheleastpowercon-sumption.
简介:Wepresentarapidsystemforpredictingbeeftendernessbymimickingthehumantactilesense.ThedetectionsystemincludesaFSpressuresensor,apowersupplyconversioncircuit,asignalamplifierandaboxinwhichthesampleismounted.AsampleofrawLongissimusdorsi(LD)muscleisplacedinthemeasuringbox;thenarodconnectedtothepressuresensorispressedintothebeefsampletoagivendepth;thereactionforceofthebeefsampleismeasuredandusedtopredictthetenderness.SensoryevaluationandWarner-BratzlerShearForce(WBSF)evaluationofsamplesfromthesameLDmuscleareusedforcomparison.Thenewdetectionsystemagreeswithestablishedprocedure95%ofthetime,andthetimetotestasampleislessthan5minutes.
简介:Inanattempttorealizeaflappingwingmicro-airvehiclewithmorphingwings,wereportonimprovementstoourpreviousfoldableartificialhindwing.Multiplehinges,whichwereimplementedtomimicthebendingzoneofabeetlehindwing,weremadeofsmallcompositehingeplatesandtinyaluminumrivets.Thebuck-tailsofrivetswereflaredafterthehingeplateswereassembledwiththerivetssothatthefolding/unfoldingmotionscouldbecompletedinlesstime,andthestraightshapeoftheartificialhindwingcouldbemaintainedafterfabrication.Foldingandunfoldingactionsweretriggeredbyelectrically-activatedShapeMemoryAlloy(SMA)wires.Forwingfolding,theactuationcharacteristicsoftheSMAwireactuatorweremodifiedthroughheattreatment.Throughaseriesofflappingtests,weconfirmedthattheartificialwingsdidnotfoldbackandarbitrarilyfluctuateduringtheflappingmotion.
简介:Fourdifferentstructuralmodelsofartificialjointsweredevelopedandthefiniteelementmethod(FEM)wasemployedtoinvestigatetheirmechanicalcharacteristicsunderstaticanddynamicconditions.ThematerialsusedintheFEMcalculationwereultra-highmolecularweightpolyethylene(UHMWPE),316Lstainlesssteel,CoCrMoalloyandTi6Al4Valloy.Thestressdistribution,strain,andelasticdeformationunderstaticanddynamicconditionswereobtained.Analysisandcomparisonofthecalculationresultsofdifferentmodelswereconducted.Itisshownthatwiththesameparametersthemodelofametallicfemurheadcoveredwithanartificialcartilagelayerismoresimilartothestructureofthenaturalhumanjointanditsmechanicalcharacteristicsarethebestofthefourmodels.
简介:目的:研究植物细胞响应机械应力的形态学变化;初步探讨壁膜连接对于植物细胞响应机械应力的意义,及其是否参与机械应力响应过程。方法:将植物单细胞包埋后进行精确机械力加载并培养数日,每天抽样进行显微观测和图像分析监测其形态变化;在此基础上进行质壁分离,并采用RGD多肽处理中断细胞壁膜连接后进行应力加载,监测其形态变化。结果:植物细胞经机械应力加载后,其分裂方向趋于垂直应力加载方向。经壁膜连接中断处理后进行加载的植物细胞失去沿主应力线垂直方向分裂的能力,细胞分裂方向呈无序状态。结论:壁膜连接特别是以RGD序列识别为基础的细胞连接参与了植物细胞对机械应力的响应过程。
简介:目的:设计靶向乙型肝炎病毒(HBV)基因保守区的人工microRNA(amiRNA),考察其对HBV基因表达的抑制作用。方法:比对HBV全基因组现有序列,选择保守区设计amiRNA,定向克隆到pcDNA6.2-GW/EmGFP-miR载体,将amiRNA载体与HBV复制载体pHBV1.31共转染HepG2细胞,72h后收取细胞上清,ELISA检测HBV表面抗原(HBsAg)及e抗原(HBeAg)的含量,荧光定量PCR检测HBVDNA含量。结果:amiRNA可显著抑制细胞上清HBsAg、HBeAg和HBVDNA的水平。结论:amiRNA作为防治HBV感染的潜在有效手段之一值得进一步深入研究。
简介:目的:探讨创伤骨科中应用人工关节治疗技术的效果。方法:选取2012年12月-2014年5月收治于本院的45例老年股骨颈骨折患者作为研究对象,收集患者的临床资料并对其进行回顾性分析,32例应用人工股骨头置换术进行治疗,13例予以全髋关节置换术进行治疗,对患者情况采用Harris髋关节评分标准进行评估,观察总结其治疗方法和疗效。结果:经治疗,45例患者全部安全度过围术期,1例出现轻度尿路感染,无假体松动与脱位发生,Harris髋关节评分为(88.67±4.85)分,优良率为95.6%。结论:创伤骨科中应用人工关节治疗技术治疗股骨颈骨折疗效显著,具有较高的安全性,可在临床上进行推广应用。
简介:目的:以类风湿性关节炎(RA)患者滑膜细胞为研究对象,明确miR-10a对滑膜细胞侵袭、迁移能力的影响及机制。方法:首先用qRT-PCR对筛选得到的异常表达miRNA进行验证,进而利用生物信息学分析结合报告基因、Western印迹方法,明确miR-10a的靶基因,最后采用Transwell、划痕实验考察miR-10a对RA成纤维细胞样滑膜细胞(FLS细胞)侵袭能力的影响。结果:miR-10a在RA患者滑膜组织及细胞中低表达;TAK1和BTRC是miR-10a的靶基因;miR-10a可促进IL-6、IL-8等炎症因子的表达;miR-10a可促进FLS细胞的侵袭、迁移。结论:miR-10a可通过调节NF-κB的活性影响RAFLS细胞的侵袭、迁移。
简介:目的:在类风湿性关节炎(RA)成纤维样滑膜(FLS)细胞中筛选并鉴定盘状结构域受体2(DDR2)的相互作用蛋白,并研究其对FLS细胞侵袭能力的影响。方法:首先利用免疫沉淀结合SDS-PAGE分离鉴定DDR2互作蛋白波形蛋白,进而采用免疫沉淀和激光共聚焦实验,进一步验证波形蛋白是DDR2的相互作用蛋白,最后采用Transwell实验考察波形蛋白对RAFLS细胞侵袭能力的影响。结果:Ⅱ型胶原刺激引起RAFLS细胞中DDR2的磷酸化水平升高,DDR2被活化,活化前后共有8个DDR2相互作用蛋白发生变化,经质谱分析,其中变化最大的是波形蛋白和膜联蛋白A2;在HEK293T细胞中,免疫共沉淀结果显示FcDDR2与波形蛋白存在相互作用;激光共聚焦结果显示在RAFLS细胞中,DDR2和波形蛋白存在共定位;下调RAFLS细胞中波形蛋白的表达后,细胞的侵袭能力较对照组显著下降。结论:波形蛋白是DDR2的相互作用蛋白,Ⅱ型胶原可引起RAFLS细胞的DDR2磷酸化水平升高,并通过波形蛋白促进RAFLS细胞的侵袭。