简介:Objective:Toinvestigatetheunderlyingneurobiologicalmechanismoftheprotectiveeffectofelectroacupuncture(EA)duringcerebralischemia-reperfusion(CI-R).Methods:Inthefirstpartofthestudy,15SDratswereevenlyrandomizedintocontrolgroup,CI-R-48hmodelgroupandCI-R-48h+EAgroup.ThecorticalapoptosisandexpressionofBcl-2andBaxproteinsineachgroupweredetectedbyflowcytometer(FCM).Inthesecondpartofthestudy,75SDratswereevenlyrandomizedintocontrol,CI-R-3min,CI-R-3min+EA,CI-R-48handCI-R-48h+EAgroups.Corticalnorepinephrine(NE)concentrationwasdetectedbyfluorescencespectrometer.CI-Rmodelwasestablishedbyocclusionofthebilateralcommoncarotidarteriesandreperfusion.EA(4~16Hz,1~3V)wasappliedafterreperfusionrespectively.Results:Inthefirstpartofthisstudy,resultsindicatedthatthenumberoftheapoptoticneuronsandtheapoptosisrateofCI-R-48hgroupweresignificantlyhigherthanthoseofcontrolgroup;whilecomparisonbetweenCI-R-48h+EAandCI-R-48hgroupsshowedthatthenumberoftheapoptoticneuronsandtheapoptosisrateoftheformergroupweresignificantlylowerthanthoseofthelatergroup(P<0.05).Incomparisonwithcontrolgroup,afterCI-48h,Baxexpressionwasup-regulatedsignificantlyandBcl-2down-regulatedmarkedly(P<0.05).ComparisonbetweenCI-R-48handCI-R-48h+EAgroupindicatedthatBaxexpressionofthelatergroupwassignificantlylowerthanthatoftheformergroup,whileBcl-2expressionofCI-R-48h+EAgroupwassignificantlyhigherthanthatofCI-R-48hgroup(P<0.05),suggestingthatEAcouldreverseCIinducedreactionsofthesetwoindexes.Inthesecondpartofthestudy,incomparisonwithcontrolgroup,NEconcentrationincerebralcortexofCI-R-3mingroupincreasedsignificantly(P<0.05);whileNEcontentofCI-R-3min+EAgroupwassignificantlylowerthanthatofCI-R-3mingroup(P<0.05).NosignificantdifferencewasfoundbetweenCI-R-3mingroupandcontrolgroupincorticalNEl
简介:Inthisstudy,61casesofischemicstrokepatientsarerandomlydividedintosurroundingneedlinggroup(n=31)andscalp-acupuncturegroup(n=30).TheischemicfocusofthebrainisdeterminedbyCTexamina-tion.Forpatientsofthesurroundingneedlinggroup,Gauge-29-30stainlesssteelfiliformneedlesareinsertedintothesurroundingscalpofthefocalprojectionregiononebyone,withtheneedle-tipstowardthecenterofthefocalprojec-tionarea,andcombinedwithotherbodyacupointsaccordingtosyndromedifferentiation.Forpatientsofscalp-acupuncturegroup,MotorArea(MS6)andSensoryArea(MS7)ofthecontralateralsideofthefocusareused.Thetreatmentisperformedoncedailyinbothgroups,with30sessionsbeingatherapeuticcourse.Afteronecourseoftreatment,insurroundingneedlingandscalp-acupuncturegroups,20and11casesarecuredbasically,10and15haveamarkedimprovement,1and4areeffective,thetherapeuticeffectoftheformergroupissignificantlysuperiortothatofscalp-acupuncturegroup.Aftertreatment,plasmaepinephrine(E)andnorepinephrine(NE)levelsofthetwogroupsdecreaseconsiderablycomparedwithpre-treatmentofeachgroup(P<0.01),andtheeffectsofsurroundingneedlingonEandNEaremoreevidentlythanthoseofscalp-acupuncture(P<0.05).ResultssuggestthatthetherapeuticeffectofacupuncturemayberelatedtothedeclineofplasmaEandNElevels.
简介:TheFifthGeneralAssemblyofWFASwasheldinSeoul,RepublicofKorea,onNovember12,2000.SheJing,ViceHealthMinisterandconcurrentDirector-GeneralofStateAdministrationofTraditionalChineseMedicinefromthePeople'sRepublicofChinaandHong-BinKang,ViceMayorofSeoul,RepublicofKorea,attendedtheopeningceremonyandadressedattheassembly.TheyspokehighlyofthecontributionsthatWFAShasmadetothedevelopmentandapplicationofacupuncturemedicine.Theypointedoutthatinthepast13yearssincetheestablishementofWFAS,fruitfuleffortshavebeenmadeforthedisseminationanddevelopmentofacupuncturemedicineintheworld.TheorganizationalstructureofWFASisbecomingmorematureintheprocessofpromotingthedevelopmentofacupuncturescienceandacceleratingthemutualunderstandingandcooperationamongacupuncturegroupsintheworld.ThedevelopmentofWFAShasenteredanewstagesinceWFA$wasadmittedintoofficialrelationswithWHO.