简介：Injectablenanoparticlecarrier,poly(ethyleneglycol)-coatedpoly(ethylcyanoacrylate)hasbeenpreparedbyasimplemethod.AtFirst,synthesizingPEGmacromonomerofpoly(ethyleneglycol)monomethyletherwithacryloylchloride,thengraftcopolymerofpoly(ethylcyanoacrylate)andpoly(ethyleneglycol)wasyieldbyfreeradicalpolymerizationofethylcyanoacrylatewithPEGmacromonomerintoluenesolvent.CharacterizationofthecopolymerhasbeenperformedbyFTIR,1H-NMRandGPCanalysis.Nanoparticleswereeasilypreparedfromtheobtainedamphiphiliccopolymer.

简介：Poly-α-aminoacidisakindofbiodegradablebiomedicalmaterial.Itisusedforthepreparationofsustaineddrug-releasedevice.Therearesomeadvantagesofthedrugdeliverydevices.Theycanprovidethetherapywithsideeffects.Thedrugre-leaseismaintainedatabeneficialrateforaprolongedtime.Thepolymermaybebiodegradedafterthedrughasbeenexhausted.

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