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简介：Objective:Tostudytheprotectiveeffectofischemicpreconditioning(Ⅰ-pre)andischemicpostconditioning(Ⅰ-post)againstischemia/reperfusion(I/R)injuryinrat'sliver.Methods:UsingratmodelofhepaticsegmentalI/Rinjury,ratsweredividedinto5groups:GroupA(shamgroup),GroupB(I/Rinjury),GroupC(Ⅰ-pregroup),GroupD(Ⅰ-postgroup)andGroupE(combinedtreatmentofⅠ-preandⅠ-post).Serumalanineaminotransferase(ALT),aspartateaminotransferase(AST),malondiaidehyde(MDA),glutathione(GSH),superoxidedismutase(SOD),glutathioneperoxidase(GSH-Px)andmyeloperoxidase(MPO)inhepatictissuesweredetermined,respectively.Inaddition,7days'survivalofGroupsB,C,DandEwereevaluated.Results:ComparedwithGroupB,GroupsC,DandEexhibitedsignificantlydecreasedALTandASTrelease,minimizedtissueinjury,suppressedvaluesofMDAandMPO,increasedactivitiesofSOD,GSH-PxandGSH(P<0.05),aswellasimprovedanimalsurvival.ThedifferencesamongGroupsC,DandEwerenotstatisticallysignificant.Conclusions:Ⅰ-pre,Ⅰ-postandcombinedtherapyofⅠ-preandⅠ-posthaveprotectiveeffectagainsthepaticI/Rinjury,whichiscorrelatedwithitsfunctionofreducingtheproductionofreactiveoxygenspecies,maintainingtheactivitiesofantioxidantsystemsandsuppressingneutrophilsrecruitment.NoadditiveeffectcanbeobtainedinGroupE.

简介：[摘要] 目的：探讨急性心肌梗死介入治疗中心律失常的护理干预效果。方法：从2020年1月至2021年5月，在我院介入治疗的94例急性心肌梗死患者。根据入院编号奇偶性分组：奇数编号的47例进入对照组，实施常规护理；偶数编号的47例进入试验组，进行有效护理干预。比较护理满意度和治疗指标。结果：相比于对照组，试验组总满意率更高（95.74%vs82.98%），患者的心率、QT离散度更低，QTC间期更大，经检验有统计学差异（P＜0.05）。结论：急性心肌梗死介入治疗中发生心律失常的患者，实施有效护理干预能改善治疗效果，提高患者满意度。

简介：摘要：“刘氏骨伤疗法”源远流长，特色鲜明，擅长外治、特色伤药外用内服，将三指按摩与用药配合，手法与练功同施，同时注重器材的使用，取得满意的临床疗效。本文主要着重介绍“刘氏骨伤”的起源、发展和其特色的疗法，让更多的人对刘氏骨伤有深入得了解。

简介：Objective:Toevaluatetheeffectsofhyperbaricoxygen(HBO)therapyonpatientswithpostbraininjuryneuralstatus.Methods:Twoto4coursesofHBOtherapyand/ormedicationswereusedtotreat320patientswhowererandomlydividedintotwogroups.Assessmentwasmadewith99mTc-ethylcysteinatedimer(99mTc-ECD)singlephotonemissioncomputedtomography(SPECT)beforeandaftertreatment.Results:TherewasasignificantdifferencebetweentheHBOtherapygroupandthenon-HBOtherapygroup.HBOtherapywassuperiortomedicationtreatmentaloneintherecoveryofclinicalsymptoms,controlofepilepsy,andresolutionofhydrocephalus(P<0.01).Conclusions:HBOtherapyhasspecificcurativeeffectsonpatientswithpostbraininjuryneuralstatus,and99mTc-ECDSPECTcouldplayanimportantroleindiagnosingpostbraininjuryneuralstatusandmonitoringthetherapeuticeffectsofHBO.

简介：Directgenetransferintosomatictissueinvivoisadevelopingtechnologywithpotentialapplicationforcancergenetherapy.Retrovirusvector,whichwasaneffectivevehicle,stillhassomedisadvantagesingeneratinghightiterrecombinantvectorsandmanipulatingtomediateinvirogenetransfer.Inthispaper,recombinantvacciniavirusvectorencodinghuman

简介：Objective:Tostudythechangesofpartialpressureofbraintissueoxygen(PbtO2)andbraintemperatureinacutephaseofsevereheadinjuryduringmildhypothermiatherapyandtheclinicalsignificance.Methods:Onehundredandsixteenpatientswithsevereheadinjurywereselectedanddividedintoamildhypothermiagroup(n=58),andacontrolgroup(n=58)accordingtooddandevennumbersofhospitalization.WhilemildhypothermiatherapywasperformedPbtO2andbraintemperatureweremonitoredfor1-7days(mean=86hours),simultaneously,theintracranialpressure,rectumtemperature,cerebralperfusionpressure,PaO2andPaCO2werealsomonitored.Thepatientswerefollowedupfor6monthsandtheprognosiswasevaluatedwithGOS(Glasgowoutcomescale).Results:ThemeanvalueofPbtO2within24hourmonitoringinthe116patientswas13.7mmHg±4.94mmHg,lowerthanthenormalvalue(16mmHg±40mmHg)ThetimeofPbtO2recoveringtothenormalvalueinthemildhypothermiagroupwasshortenedby10±4.15hourscomparedwiththecontrolgroup(P<0.05).Thesurvivalrateofthemildhypothermiagroupwas60.43%,higherthanthatofthecontrolgroup(46.55%).Aftertherecoveryofthebraintemperature,PbtO2increasedwiththeriseofthebraintemperature.Conclusions:Mildhypothermiacanimprovethesurvivalrateofsevereheadinjury.ThetechniqueofmonitoringPbtO2andthebraintemperatureissafeandreliable,andhasimportantclinicalsignificanceinjudgingdiseaseconditionandinstructingclinicaltherapy.