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简介：Theclinicalpresentationsofgestationalchoriocarcinomavarymarkedly,andamisdiagnosiscouldbemadeinatypicalpatientsifsimplyrelyingonclinicalfeatures.Laparoscopicresectionofuterinemasslesionisrarelyusedingestationalchoriocarcinomadiagnosisbecauseofthefearofheavybloodlossanddistantmetastasis.Fivepatientswhowerepreoperativelydiagnosedashavingcornualpregnancyunderwentlaparoscopicresectionofmasslesionandthenprovedtohavegestationalchoriocarcinomabasedonpathologicalexaminations.Chemotherapywasstartedwithintwodaysaftersurgery,andtherateofcompleteremissionwas100%.Themeanfollow-uptimewas29.8±19.1months,andnopatientshowedsignsofrelapse.Laparoscopicresectionofuterinemassfollowedbytimelypostoperativechemotherapymaybeaneffectiveandsafewaytoobtainpathologicresultsinpatientswithsuspectedgestationalchoriocarcinoma.

简介：Lymphomararelyoccursduringpregnancy,makingthisconditiondifficulttodefine.Lymphomasthatoccurinreproductiveorgansduringpregnancyexhibituniqueclinicalcharacteristics.Amongthelimitedcases,non-Hodgkin'slymphoma(NHL)showsaconsiderablyhigherincidenceratethanHodgkin'slymphoma(HL);NHLalsodisplaysclinicalcharacteristics,suchashighaggressiveness,advancedstage,andpooroutcome.Thisstudyreportsonfourcasesoflymphomasinnon-gonadalorgans(HL,n=2;NHL,n=2)duringpregnancy.Thetumorsrapidlyprogressedinallpatientsduringpregnancybutremittedattheendofpregnancyand/ortherapy.ThetwoHLcaseswerenodularsclerosisclassicalHLandtreatedwithchemotherapyafterterminatingthepregnancy.OneoftheNHLcaseswasprimarycutaneousfollicularcenterlymphoma,aBcell-derivedindolentlymphoma.Thepatientwasfollowedupwithoutanytherapyafterterminatingherpregnancy.Theothercasewasafollicularlymphomagrade3B,whichwastreatedwithchemotherapyafterdelivery.Wealsoconductedaliteraturereviewof165lymphomacasesoccurringduringpregnancyreportedfrom1976to2013torevealthecorrelationbetweenpregnancyandlymphomaprogression.Immunohistochemistrystudieswereperformedtodeterminetheexpressionofestrogen/progesteronereceptors(ER/PR),andERwasweaklypositiveandsporadic.Weconcludedthatlymphomasoccurringduringpregnancyshouldbemanagedwithapromptandreasonabletreatment.Highestrogenlevelinmaternalbodymayaffectlymphomaprogression.