简介:从连翘果实中分离了三种苯乙醇甙类化合物,calceolariosideA(1),plantainosideA(2)和forsythosideA(3),用光谱方法鉴定了它们的结构。1和2系首次从本属植物中分离得到。通过1H1HCOSY和13C1HCOSY对3的氢信号与碳信号进行正确归属,补充文献的不足。3能显著促进ConA诱导的淋巴细胞转化,提示其具有增强免疫作用,该活性未见报导。
简介:Marginatol(1),anewisopimarenediterpenoid,andfiveknowncompounds8(14),15-sandera-copimaradiene-1α,9α-diol(2),8(14),15-sanderacopimaradene-1α6β,9α-triol(3),germacrone(4),trans-ethylp-methoxycinnamate(5)andn-pentadecane(6)wereisolatedfromthehexaneextractofKaempferiamarginataCarey.Thestructureofmarginatol(1)wasestablishedas8(14),15-isopimaradiene-6α-olonthebasisofspectraldata(IR,MS,^1h-^-1H13^C-^1HNOESYandHMBC).Compounds2,3and4wereisolatedforthefirsttimefromthisplant.
简介:H3,ahomogeneousacidicpolysaccharidewasobtainedfromtheseedsofCuscutachinensisLam.Itsstructurewascharacterizedforthefirsttimebychemicalandspectroscopicmethodstobeahighlybranchedheteropolysaccharidewithmeanmolecularweightofmorethanlxl0^6.Itwascomposedof1,6-1inked-β-DGalp,1,4-linked-β-DGalp,1,4-1inked-β-DGalA,1,3,6-1inked-β-DGalpand1,2,4-1inkedRhap,withbranchingpointsatO-2or0-4of1,2,4-1inkedRhapand0-3of1,3,6-1inked-β-DGalp.Itssidechainsincluded1-1inkedAraf,1,5-1inkedArafand1,3,5-1inkedArafatO-3of1,6-1inkedGalpinthemainchain.
简介:Artesunaeisaderivativeofqinghaosu,withasesquiterpenestructure.Thespecificactionandtheclinicalusesofartesunateareonthepreliminarystage,ontheonehand,artesunatehasspecificactionofbothantiinflammationandantivirus,andalsohasprotectiveeffectonthepulmonaryalveolarmacrophages,whuichmaybeadvantageoustothetreatmentoftheairwaynon-specificinflammationofasthma,.Ontheotherhand,qinghaousuhastheactivitiestorelaxvascularsmoothmuscleandtocausehypotension.Theexpectorantaction,theantitussiveactionandtheantuiasthmaticactionofqinghaosuwerepreported.Artesunatemayalsohaveantiasthmaticactivity,becausetheantimalarialpotencyofartesunateisstrongerthanthatofqinghaosu,andArtesunatecanblockCa^2+influxbyinhibitingcalcium-dependentchloridecurrent.Themainaimsofthispaperaretoinvestigatethesite,themode,andthemechanismofartesunateactiononisolatedtrachealsmoothmusclefromtheguinea-pig.
简介:从黄芩根中首次分离出一个新黄酮碳糖甙,白杨素8CβD葡萄糖甙和一个已知苯乙醇甙,acteoside。
简介:EfectsofArtesunateonTrachealSmoothMusclefromtheGuineapigPostgraduate∶MaoShengYangSupervisor∶AsociateProf.JianChuXiaoDepa...