简介:AbstractBackground:Few studies have assessed the relationship between multimorbidity patterns and mortality risk in the Chinese population. We aimed to identify multimorbidity patterns and examined the associations of multimorbidity patterns and the number of chronic diseases with the risk of mortality among Chinese middle-aged and older adults.Methods:We used data from the China Kadoorie Biobank and included 512,723 participants aged 30 to 79 years. Multimorbidity was defined as the presence of two or more of the 15 chronic diseases collected by self-report or physical examination at baseline. Multimorbidity patterns were identified using hierarchical cluster analysis. Cox regression was used to estimate the associations of multimorbidity patterns and the number of chronic diseases with all-cause and cause-specific mortality.Results:Overall, 15.8% of participants had multimorbidity. The prevalence of multimorbidity increased with age and was higher in urban than rural participants. Four multimorbidity patterns were identified, including cardiometabolic multimorbidity (diabetes, coronary heart disease, stroke, and hypertension), respiratory multimorbidity (tuberculosis, asthma, and chronic obstructive pulmonary disease), gastrointestinal and hepatorenal multimorbidity (gallstone disease, chronic kidney disease, cirrhosis, peptic ulcer, and cancer), and mental and arthritis multimorbidity (neurasthenia, psychiatric disorder, and rheumatoid arthritis). During a median of 10.8 years of follow-up, 49,371 deaths occurred. Compared with participants without multimorbidity, cardiometabolic multimorbidity (hazard ratios [HR] = 2.20, 95% confidence intervals [CI]: 2.14-2.26) and respiratory multimorbidity (HR= 2.13, 95% CI:1.97-2.31) demonstrated relatively higher risks of mortality, followed by gastrointestinal and hepatorenal multimorbidity (HR= 1.33, 95% CI:1.22-1.46). The mortality risk increased by 36% (HR= 1.36, 95% CI: 1.35-1.37) with every additional disease.Conclusion:Cardiometabolic multimorbidity and respiratory multimorbidity posed the highest threat on mortality risk and deserved particular attention in Chinese adults.
简介:目的:探讨冬季常温碘伏和加温38℃碘伏进行会阴擦洗消毒效果。方法:2012年10月至2013年3月在我院妇科住院术后留置导尿管的300例患者随机岔为观察组150例和对黑组150例,两组患者在年龄和疾病分组方面无显著差异(P〉O05)。观察组采用将o.5%碘伏加热到(38±1)℃行会阴擦洗消毒。对照组采用室温下(15-20℃)7.5%碘伏消毒液擦洗会阴,两种温度的碘伏使用前同样测量温度。比较两组病人的舒适度和泌尿系感染率。结果:实验组病人舒适度明显增加(|D〈o.05),实验纽感染率低于对照组(p〈O.05)。结论:38℃加温碘伏用于会阴擦洗不仅消毒交果不受影响.优于常温下碘伏,还增强病人的舒适度,体现人性化服务理念.
简介:摘要目的探索分析经生理盐水稀释的0.5%布比卡因在腰麻剖宫产中的最佳剂量。方法将我院2016年1月—10月期间收治的腰-硬联合麻醉条件下行剖宫产术的产妇150例作为研究对象,随机分为3组,各50例。于L2-3椎间隙穿刺成功后,向蛛网膜下腔注入0.5%布比卡因。按照剂量不同,分为7.5mg组、8.5mg组、9.5mg组。将3组产妇麻醉效果进行对比。结果三组腰麻后感觉阻滞达到T6的时间相对接近(P>0.05);硬膜外补充用药后麻醉效果均达到手术要求。三组麻醉效果优良率相对接近,均取得良好效果。8.5mg组及9.5mg组麻醉后5、10、15min血压较麻醉前明显下降,其心率明显增快(P<0.05),低血压发生率明显超过7.5mg组(P<0.05);相比之下,7.5mg组血流动力学相对稳定。7.5mg组的低血压、恶心呕吐及寒战发生率显著低于8.5mg组和9.5mg组(P<0.05)。结论在经生理盐水稀释的0.5%布比卡因7.5mg腰麻状态下实施剖宫产术,可以产生良好的麻醉效果,具有较高的安全性,值得推广应用。
简介:摘要目的对比静脉留置针全部置入与外留0.1-0.5cm的留置时间和不良事件发生情况。方法选取2016年11月~2017年10月在我院住院的150例需行静脉留置针穿刺患者为研究对象,将其随机分为两组,每组75例。对照组为静脉留置针全部置入,观察组为静脉留置针外留0.1-0.5cm,对两组的留置时间和不良事件发生率进行比较。结果两组患者的静脉留置针留置时间对比无显著差异(P>0.05);观察组中的穿刺点红肿发生率、留置针弯曲打折发生率均明显低于对照组,两组数据存在显著差异(P<0.05)。结论在进行静脉留置针穿刺时外留0.1-0.5cm再固定,可降低不良时间发生率,且静脉留置针的使用时间较长。
简介:摘要目的探讨中枢神经细胞瘤应用0.5T鑫高益影像进行诊断的具体概况,以便能够更加深入和具体的了解该疾病。方法随机选择2013年1月至2014年1月入住我院接受常规治疗并通过病理和手术证实为中枢神经细胞瘤的6例患者作为研究对象,对6例神经细胞瘤患者的临床诊断和治疗资料进行、回顾性分析,探讨0.5T鑫高益影像诊断在疾病诊断中的应用和效果。结果在0.5T鑫高益影像下,6例患者的细胞瘤均在侧脑室内形成,且位置比较靠前,在Monro孔附近病灶多。细胞瘤与透明隔处在一种宽基底相连的状态,整个细胞瘤的边界非常清晰但信号呈现不均匀形式。有1例细胞瘤患者同时伴有出血症状。结论处在侧脑室内中前部且0.5T鑫高益影像下边界清晰但信号不均匀的肿瘤通常多为中枢神经细胞瘤。