简介：BackgroundFlavonoidsfromfruits,vegetablesandplantshavebeenwidelystudiedontheireffectsofimprovinglipidemia,anti-inflammation,anti-plateletaggregationandanti-oxidativeactivities.However,wedon'tknowifflavonoidsfromrapebeepollenhavethesameeffectsinpatientswithdyslipidemia(DL),type2diabetesmellitus(T2DM),andcerebralinfarction(CI).MethodsThestudyinvolvedwithpatientsselectedanddividedinto4groups,30casesofDL,ofT2DM,ofCIandhealthcontrol(HC)foreach.Fortymgflavonoidsfromrapebeepollenadministratedorallytwiceadayfortwomonths.Bloodsugar(BG),totalcholesterol(TC),triglyceride(TG),highdensitylipoprotein-cholesterol(HDL-C),lowdensitylipoprotein-cholesterol(LDL-C),whiteblood-cellcounts(WBC),plateletcounts(PLT),high-sensitivityC-reactiveprotein(hsCRP)andmalondialdehyde(MDA)wereanalyzedinfourgroupsbeforeandaftertakingflavonoidsfortwomonths.Results(1)BasiclevelsofTC,BG,WBC,PLTandhsCRPingroupsofT2DM,CI,andTGandMDAingroupsofDL,T2DMandCIweresignificantlyhigherthanthoseinHC(P<0.05-0.001).(2)ThelevelsofTG,WBC,PLT,hsCRPandMDAweresignificantlydecreased,whileHDL-Cwasremarkablyincreasedaftertakingflavonoidsfortwomonths(P<0.05-0.001)ingroupofDL,T2MD,andCI.TheseindexeswerenotdifferentinthegroupofHCaftertakingflavonoids(P>0.05).ConclusionsTheresultscouldindicatemetabolicdisturbance,inflammation,andhighoxidativestressinpatientswithdyslipidemisa,type2diabetesmellitus,andcerebralinfarction.Theflavonoidsfromrapebeepollenmayhaveeffectsofantioxidantactivity,improvinglipids,andanti-inflammationonthesepatients.