简介:AIM:Toevaluatethelong-termresultsandcomplicationsofahmedglaucomavalve(AGV)implantationinrefractoryglaucoma.·METHODS:Aretrospectivereviewof13patients(13eyes)withrefractoryglaucomawhounderwentAGVimplantationandhadaminimumfollow-upof18monthswasperformed.Allpatientsunderwentacompleteophthalmologicexaminationandintraocularpressure(IOP)measurementbeforesurgeryandat1month,3months,6months,1yearaftersurgeryandyearlyafterwards.Complicationsandthenumberofantiglaucomamedicationsneededwererecorded.·RESULTS:Meanagewas27.3±16.0years.Alleyes(100%)hadatleastonepriorincisionalsurgery.Meanfollow-upwas61.3±30.8months.IOPwasreducedfromameanof35.0±7.0mmHgto18.2±7.9mmHgat12monthsandto17.0±4.1mmHgat96months(P<0.05)withalowernumberofmedicationsfrombaseline,76.9%patientsrequiredadditionalprocedurestoachievethesuccesscriteriasetbypreviouslypublishedseries.Themostcommoncomplicationswereencapculatedcystformationineighteyes(61.5%)andtubeexposureinfoureyes(30.8%).·CONCLUSION:EncapsulatedcystformationwasthemostcommoncomplicationwhichhinderedsuccesfulIOPcontrolafterAGVimplantinsertionforrefractoryglaucoma.Despitecystexcisionwithanti-fibroticagents,successfulIOPreductionwasnotachievedin76.9%ofthepatientswithoutantiglaucomamedication.
简介:·Glaucomaisoneoftheleadingcausesofvisualimpairmentandblindnessworldwide.Ofknownriskfactorsforglaucoma,anincreasedinintraocularpressureismosthighlycorrelatedwithglaucomatousdamage.Irrespectiveofthecause,apoptosisoftheretinalganglioncellsistheeventualoutcome.Itiswidelyacceptedthatglaucomaisaneurodegenerativediseasethatisstronglycorrelatedwithcentralnervoussystemdisorders,suchasAlzheimer’sdisease.Thesetwodisordersalsosharesomesimilaritiesinpathogenicmechanisms.Recentstudiessuggestthatthetransientreceptorpotentialcanonical6channelcouldworktogetherwithbrain-derivedneurotrophicfactortopromoteneuronsurvivalinbrainandretina.Inthisstudy,weproposethattransientreceptorpotentialcanonical6maycontributetothepathogenesisofhumanglaucomaandbecomeapotentialtherapeutictarget.
简介:空气娃娃深知自己是世上所有生命,最亲密无间的挚友、好伙伴。是呀,无论人类、动物、鸟类、昆虫、植物都需要时时刻刻呼吸空气。倘若没有空气,世上的一切生命将无法生存。
简介:摘要:“山形”管束和“教堂窗形”管束是常规凝汽器两种常见的管束布置型式,本文通过对凝汽器汽侧流动特性的简化,针对两种管束型式下凝汽器汽侧凝结与换热过程分析计算,从汽侧流场分布、压损、传热系数、凝结率等参数的对比上,综合考量冷却管束的布置。
简介:【摘要】目的:探究吲哚菁绿辅助PHACO+IOL植入术治疗白内障的效果。方法:将2021年12月至2024年2月我院收治的80例白内障患者,随机分为观察组、对照组,各40例。对照组、观察组分别实施PHACO+IOL植入术治疗、吲哚菁绿辅助PHACO+IOL植入术治疗。结果:在治疗有效率比较方面,观察组为95.00%,对照组为75.00%,观察组明显高于对照组,有统计学意义(P<0.05);结论:实施吲哚菁绿辅助PHACO+IOL植入术治疗在白内障患者的治疗中,可以提升白内障患者的治疗有效率,提高手术的精准度,降低并发症风险,缩短手术时间以及提高手术成功率,值得参考。