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简介：Ｃｏｍｐｒｅｈｅｎｓｉｖｅｉｎｄｉｃｅｓｏｆｅａｒｌｙｊｕｄｇｅｍｅｎｔｆｏｒｅａｒｔｈｑｕａｋｅｓｅｑｕｅｎｃｅｔｙｐｅｂｙｐａｔｅｒｎｒｅｃｏｇｎｉ┐ｔｉｏｎＣＵＩ－ＹＩＮＧＺＨＯＵ１）（周翠英），ＹＵ－ＸＩＡＺＨＡＮＧ２）（张宇霞），ＨＯＮＧ...

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简介：CellResearchispublishedmonthlybyNaturePublishingGroupinpartnershipwithShanghaiInstitutesforBiologicalSciences(SIBS),ChineseAcademyofSciences(CAS).CellResearch,whichpublishesexclusivelyinEnglish,isChina'sleadingjournalinthelifescienceswithacurrentImpactFactorof3.426(Thomson-ISI,PA,USA2007).Thejournalisindexed/abstractedinIndexMedicus/Medline/PubMed,ScienceCitationlndex,CurrentContents-lifeSciences,SciSearchandISIWebofScience,ChemistryAbstracts,BIOSIS,VINITI,Cbinainfo(CD&Web),CJFD(CD&Web),CJCDandCEPS,etc.ScopeCellResearchisaninternationaljournalpublishingpeer-reviewedoriginalarticles,invitedreviews,commentaries,andshortcommunications.Thejournalhasaninternationalauthorshipandabroadscopeinbasicresearchofcellbiology,molecularcellbiology,includingcellgrowthanddifferentia-tion,signaltransduction,apoptosis,stemcells,development,immunology,neurosciences,plantcellbiology,chromatinmodulation,epigeneticsandtranscription.EditorialManuscriptsshouldbesubmittedonlineathttp://www.nature.com/crorhttp://www.cell-research.com.Howeverifyouhaveproblems,pleasecontactEditorialOfficeatcellres@sibs.ac.cn.DetailedInstructionsforAuthorsarealsoavailableattheabovewebsites.PublisherExceptforcompaniesbasedinmainlandChina,allbusinesscorrespondenceandenquiriesaboutsupplementpublication,sponsorshipopportunitiesandadvertisingshouldbeaddressedtoNaturePublishingGroup(NPG).NickCampbell,AssociatePublisher,ExecutiveEditor:NPGNatureAsia-Pacific,MacmillanPublishers,LockedBag1,PrahranVIC3181,Australia.Tel:+61(0)398251028;Fax:+61(0)398251010.E-mail:n.campbell@natureasia.com

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简介：AbstractBackground:Recent studies using mass drug administration (MDA) of antibiotics to entire communities have focused global attention on the unique ethical challenges of MDA of antibiotics in research and public health interventions. However, there is no specific guidance for Research Ethics Committees (RECs) or Institutional Review Boards (IRBs) to review such trials. We surveyed the literature to identify the unique ethical challenges and to strengthen the competencies of RECs or IRBs in low- and middle-income countries (LMICs) in their ethical reviews of these trials.Methods:We employed a desk review. We searched PubMed, Web of Science, and Google Scholar, combining terms for "mass drug administration" with terms for "research ethics committees," "institutional review boards," and "ethics." We reviewed citations of search results to retrieve additional articles. Only articles published and indexed in the above databases up to 6 January 2022 in English were included. Abstracts (without full articles), books and articles that had exclusive veterinary and environmental focus were excluded. We synthesized the literature to identify particularly challenging ethical issues relevant to antibacterial MDA trials in LMICs.Results:The most challenging ethical issues can be categorised into four broad domains: determining the social value of MDA, assessing risks and benefits, engaging all stakeholders meaningfully, and study design-related ethical challenges. These four domains interact and impact each other. Together, they reveal the need for RECs/IRBs to review MDA studies through a broader lens than that of clinical trials per se. From our findings, we propose a framework to guide the RECs and IRBs in LMICs to perform the initial and continuing review of antibiotic MDA trials. We also recommend strengthening the competencies of LMIC RECs or IRBs through ongoing training and collaboration with RECs or IRBs from high-income countries.Conclusions:REC/IRB review of research using MDA of antibiotics plays a critical role in assuring the ethical conduct of MDA studies. Local RECs/IRBs should be empowered to review MDA studies comprehensively and competently in order to advance scientific knowledge about MDA and promote improved global health.

简介：TheGroupofNuclearStructureResearchatIMPhasdevotedmuchefforttothestudyofin-beam-rayspectroscopyandγ-decayspectroscopy.Oneterminalforin-beam-rayspectroscopyhasbeennewlybuiltupin2016.Asforγ-decayspectroscopy,twopointsneedtobeemphasized.Inordertostudythein-beam-rayspectroscopy,aballwasplacedattheterminalofnewTL2beamline.Threequadrupolemagnetsfollowingthedipolemagnetarethemainbuildingblocksalongthebeamline.Theballconsistsof8cloverand16HPGedetectorswithaCsIballinsidetoselectthechargedparticlechannel.Awallisolatingtheballfromthequadrupoleswasusedtoshieldtheradiationproducedbytheacceleratoranddepositingenergyinthedetectors,whichmayresultinahighbackground.Theinstallationwasfinishedin2016andtheexperimentforin-beam-rayspectroscopyisexpectedtoperformin2017.

简介：TheGroupofNuclearStructureResearchatIMPhasdevotedmuchefforttothelifetimemeasurementsoflowlyingexcitedstatesvia??fasttimingcoincidence.Twoexperimentswereperformedin2015attheradioactivebeamlineRIBLL[1]andgas-filledrecoilseparatorSHANS[2].

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简介：在这篇论文，我们建议在设计的系统(SE)的申请被相信中央到进步和生长的选择研究话题。作为一项职业活动，并且作为一项智力的活动，系统工程有强壮的连接到决定分析，操作研究，工程管理，优秀管理，和系统设计的如此的联系学科。当集中于设计研究的系统时，我们应该在设计更仔细对应于为相关学科是更相关的那些的本质和其它的系统的题目之间区分。

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简介：The20thcenturyisacenturyinwhichhumanmaterialcivilizationandmedicinedevelopedthemostrapidly,manycausesofdiseasesunknownbeforewerefoundmolecularly,manydiseasesorterminaldiseasesuncurablebeforewerecuredwithnewtherapeuticmethods,manyfatalcontagiousdiseasesthathadcausedcorpsoverthewildernesswerecontrolledeffectively,cathetertechniquesandoperationscouldbeusedanywhereinthehumanbodysolongastheywereneeded,andnewdiagnosticandtherapeutictechniquesemergedoneafteranother;medicalprogressmadeanever-lastingcontributiontohumanhealth.

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简介：TheSingaporeseimicnetworkandtheseismicityofSingaporearebrieflydescribed,thefourtremoreventsexperiencedbySingaporearediscussedandthegroundresponsesofdifferentstationsarecompared,Thetremorincidentstandingoperationprocedureisalsoprsented.