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简介:AbstractThe repair of bone defects, especially for the large segment of bone defects, has always been an urgent problem in orthopedic clinic and attracted researchers’ attention. Nowadays, the application of tissue engineering bone in the repair of bone defects has become the research hotspot. With the rapid development of tissue engineering, the novel and functional scaffold materials for bone repair have emerged. In this review, we have summarized the multi-functional roles of osteoclasts in bone remodeling. The development of matrix-based tissue engineering bone has laid a theoretical foundation for further investigation about the novel bone regeneration materials which could perform high bioactivity. From the point of view on preserving pre-osteoclasts and targeting mature osteoclasts, this review introduced the novel matrix-based tissue engineering bone based on osteoclasts in the field of bone tissue engineering, which provides a potential direction for the development of novel scaffold materials for the treatment of bone defects.
简介:摘要:自1988年国家主导进行试点以来,工程监理行业在建设工程监理制度的规范下实现了快速发展,取得了优异成绩,政府、协会与监理企业相结合的行业管理体系逐渐成型,为工程建设发展奠定了良好的基础。但从实际发展来看,工程监理领域仍然问题频出,如工程监理所承担的责任界定不明,监理服务标准缺失,高素质人才流失且愈演愈烈,种种问题严重影响着工程监理行业的未来发展。为此,文章对工程监理行业发展情况进行了概述,并对当前工程监理行业发展问题进行了探讨,提出了完善法规制度、坚守职业伦理、注重文化引领、加大创新力度、加强队伍建设等对策,多措并举力促工程监理实现高质量发展。
简介:摘 要:随着工程造价市场的不断深化改革,定额和工程造价资质的取消,工程造价咨询企业要“破茧重生”,工程造价数据库的建立显得十分重要。论文将工程造价咨询企业数据库的建立作为核心进行探究,首先简要介绍了工程造价数据库, 然后指出了数据库建立中存在的问题,最后提出了做好数据库建设的措施,希望能够为此类项目提供一定参考。
简介:摘要:预制板道床因其工程实体的施工质量、建设成本及后期的养护维修等方面的优势,并且符合“绿色建造”的理念,目前已在轨道交通城交通中成功应用,但地下线其施工空间有限,各专业接口众多,尤其在隔振垫预制板道床区段的排水接口是轨道工程设计的重点。由于深圳市城市轨道交通14号线是全国城市轨道交通中全线采用装配式预制板道床最长的一条线路,本文将结合深圳市城市轨道交通14号线轨道工程经验,着重对隔振垫预制板道床设计、区间轨道排水设计进行详细介绍。