简介:ThisjournalisestablishedbytheInstituteofEngineeringMechanics(IEM),ChinaEarthquakeAdministration,topromotescientificexchangebetweenChineseandforeignscientistsandengineerssoastoimprovethetheoryandpracticeofearthquakehazardsmitigation,preparedness,andrecovery.
简介:Interestinthenonlinearpropertiesofmulti-modeopticalwaveguideshasseenarecentresurgenceonaccountofthelargedimensionalityaffordedbytheplatform.Thelargevolumeofmodesinthesewaveguidesprovidesanewspatialdegreeoffreedomforphasematchingnonlinearopticalprocesses.However,thisspatialdimensionisquantized,whichnarrowstheconversionbandwidthsofintermodalprocessesandconstrainsspectralandtemporaltailoringofthelight.Hereweshowthatbyengineeringtherelativegroupvelocitywithinthespatialdimension,wecantailorthephase-matchingbandwidthofintermodalparametricnonlinearities.Wedemonstrategroup-velocity-tailoredparametricnonlinearmixingbetweenhigher-ordermodesinamulti-modefiberwithgainbandwidthsthataremorethananorderofmagnitudelargerthanthatpreviouslythoughtpossibleforintermodalfour-wavemixing.Asevidenceofthetechnologicalutilityofthismethodology,weseedthisprocesstogeneratethefirsthigh-peak-powerwavelength-tunableall-fiberquasi-CWlaserintheTi:sapphirewavelengthregime.Moregenerally,withthecombinationofintermodalinteractions,whichdramaticallyexpandthephase-matchingdegreesoffreedomfornonlinearoptics,andintermodalgroup-velocityengineering,whichenablestailoringofthebandwidthofsuchinteractions,weshowcaseaplatformfornonlinearopticsthatcanbebroadbandwhilebeingwavelengthagnostic.
简介:Datingbackto1933,SCNU'sPhysicsdisciplinewasselectedforthenationalproject"World-ClassDisciplineDevelopment"bytheMinistryofEducationin2017.CurrentlytheSchoolacceptsanaverageof1800full-timeundergraduatesand500postgraduateresearchstudents,producingapproximately20000graduatessinceitsfoundation.
简介:Overthepastdecades,cellsurfacecharge,althoughexperimentallyobserved,hasnotbeenwellunderstoodparticularlyfromtheviewpointofbiophysics.Ourrecentstudieshaveshownthatallcancercellsexhib让negativesurfacechargesthataredirectlyproportionaltothesecretedlacticacid,auniquecancermetaboliccharacteristic:highrateofglycolysis.Wehavethereforedesignedanddevelopedasetofelectrically-charged,fluorescent,andsuper-paramagneticnanoprobes,capableofsensitivedetectionofcancercellsbasedonthesurfacecharges.Theseprobesareutilizedtobindontocellsviaelectrostaticreactionforcaptureandmagneticseparation.Inthisfashion,weareabletocharacterizecellsurfacechargesthatareregulatedbydifferentmetabolicpatterns,thereforeeffectivelydistinguishingthecancercellsfromthenormalcells.All22cancercellsofdifferentorgansarefoundtobenegativelychargedthereforeboundstronglybythepositively-chargednanoprobes,whereasthenormalcellsshowinsignificantbindingtothenanoprobesofeitherchargesigns(positiveornegative).Thisfindingsuggeststhatalltestedcancercellsarenegatively-chargedandnormalcellsareeithercharge-neutralorslightlypositive.Fordiagnosis,cancercellscanbedetected,electrostaticallybound,andmagneticallyseparatedinbloodbychargedandsuper-paramagneticnanoprobes.Intherapeutics,circulatingcancercells(CTCs)canbefilteredandremovedinacontinuousfashiontoreducetheriskofcancermetastasis.Ifsuccessful,thisnewnanotechnologywillrevolutionizeearlycancerdiagnosisandpotentiallyenablenewtherapeuticsinclinicalsettings.
简介:Compositenanofibermembranesbasedonbiodegradablepoly(lacticacid)(PLA)andcellulosenanofibrils(CNF)wereproducedviaelectrospinning.TheinfluenceofCNFcontentonthemorphology,thermalproperties,andmechanicalpropertiesofPLA/CNFcompositenanofibermembraneswerecharacterizedbyfieldscanningelectronmicroscopy(FE-SEM),differentialscanningcalorimetry(DSC),thermogravimetricanalysis(TGA),anddynamicmechanicalanalysis(DMA),respectively.TheresultsshowthatthePLA/CNFcompositenanofiberswithsmooth,free-beadsurfacecanbesuccessfullyfabricatedwithvariousCNFcontents.TheintroductionofCNFisaneffectiveapproachtoimprovethecrystallineability,thermalstabilityandmechanicalpropertiesforPLA/CNFcompositefibers.TheYoung’smoduliandtensilestrengthofthePLA/CNFcompositenanofiberreach106.6MPaand2.7MPawhentheCNFcontentis3%,respectively,whichareonetimeshigherand1.5timesthanthoseofpurePLAnanofiber.Additionally,thewatercontactangleofPLA/CNFcompositenanofibermembranesdecreaseswiththeincreaseoftheCNFloading,resultingintheenhancementoftheirhydrophilicity.
简介:Thisresearchexplorestheprospectoffabricatingaface-centeredcubic(fee)Ni-basealloycladding(Inconel690)onanfeeFe-basealloy(316Lstainless-steel)havingimprovedmechanicalpropertiesandreducedsensitivitytocorrosionthroughgrainboundaryandmicrostructureengineeringconceptsenabledbyadditivemanufacturing(AM)utilizingelectron-beampowderbedfusion(EPBF).TheuniquesolidificationandassociatedconstitutionalsupercoolingphenomenacharacteristicofEPBFpromotes[100]texturedandextendedcolumnargrainshavinglowerenergygrainboundariesasopposedtorandom,high-anglegrainboundaries,butnocoherent{111}twinboundariescharacteristicofconventionalthermo-mechanicallyprocessedfeemetalsandalloys,includingInconel690and316Lstainless-steel.Inadditionto[100]texturedgrains,columnargrainswereproducedbyEPBFfabricationofInconel690claddingson316Lstainless-steelsubstrates.Also,irregular2-3pimdiameter,lowenergysubgrainswereformedalongwithdislocationdensitiesvaryingfrom10^8to10^9cm^-2,andahomogeneousdistributionofCH3C6precipitates.Precipitateswereformedwithinthegrains(with-3μminterparticlespacing),butnotinthesubgrainorcolumnargrainboundaries.Theseinclusive,hierarchicalmicrostructuresproducedatensileyieldstrengthof0.527GPa,elongationof21%,andVickersmicroindentationhardnessof2.33GPafortheInconel690claddingincontrasttoatensileyieldstrengthof0.327GPa,elongationof53%,andVickersmicroindentationhardnessof1.78GPa,respectivelyforthewrought316Lstainlesssteelsubstrate.AgingofboththeInconel690claddingandthe316Lstainless-steelsubstrateat685℃for50hprecipitated623C6carbidesintheInconel690columnargrainboundaries,butnotinthelow-angle(andlowenergy)subgrainboundaries.Incontrast,Cr23C6carbidesprecipitatedinthe316Lstainless-steelgrainboundaries,butnotinthelowenergycoherent{111}twinboundaries.Consequently,the
简介:Er^3+-dopedSrBi4Ti4O15-Bi4Ti3O12(SBT-BIT-xEr^3+,x=0.00,0.05,0.10,0.15and0.20)inter-growthceramicsweresynthesizedbythesolid-statereactionmethod.Structural,electricalandup-conversionpropertiesofSBT-BIT-xEr^3+wereinvestigated.Allsamplesshowedasinglephaseoftheorthorhombicstructure.RamanspectroscopyindicatedthattheEr^3+substitutionforBi^3+atAsitesofthepseudo-perovskitelayerincreasesthelatticedistortionofSBT-BIT-xEr^3+ceramics.ThesubstitutionofBi^3+byEr^3+leadstoadecreaseofdielectriclosstanδandanincreaseofconductivityactivationenergy.Piezoelectricconstantd33wasslightlyimproved,butdielectricconstantwasdecreasedwiththeEr^3+doping.TheSBT-BIT-xEr^3+ceramicwithx=0.15exhibitstheoptimizedelectricalbehavior(d33~17pC/N,tanδ~0.83%).Moreover,twobrightgreen(532and548nm)andonered(670nm)emissionbandswereobservedunderthe980nmexcitation.Optimizedemissionintensitywasalsoobtainedwhenx=0.15fortheSBT-BIT-xEr^3+ceramic.Therefore,thiskindofceramicsoughttobepromisingcandidatesformultifunctionaloptoelectronicapplications.